Hantaviruses are viruses transmitted mainly by wild rodents, which cause severe syndromes in humans. In the context of the current outbreak involving the Andes virus on board the cruise ship MV Hondius, the Institut Pasteur (Paris) is at the forefront of the response. The National Reference Centre (CNR) for Hantaviruses is based at the Institut Pasteur, which receives samples from people living in French exhibiting symptoms for analysis. In this news article, we provide an update on the disease, its modes of transmission, the risks involved and prevention recommendations.