PRINCIPAUX THÈMES IMPLIQUANT LE CNR

• Développement de techniques moléculaires d'identification des trois espèces de corynebactéries pouvant héberger le gène tox.
• Développement de techniques de typage des isolats de corynebactéries du complexe diphtheriae en remplacement de la ribotypie.

RAPPORTS D'ACTIVITÉ DE L'UNITÉ

• 2013
• 2012
• 2011
• 2010
• 2009
• 2008
• 2007
• 2006

PUBLICATIONS

• LAUNAY O, TONEATTI C, BERNEDE C, NJAMKEPO E, PETITPREZ K, LEBLOND A, LARNAUDIE S, GOUJON C, UNGEHEUER MN, AJANA F, RACCURT C, BEYTOUT J, CHIDIAC C, BOUHOUR D, GUILLEMOT D, GUISO N. Antibodies to tetanus, diphtheria and pertussis among healthy adults vaccinated according to the French vaccination recommendations Hum Vaccin (2009): 5(5) 341-346
• BONMARIN I GUISO N, LEFLECHE-MATEOS A, PATEY O, GRIMONT P, LEVY-BRUHL D. Diphtheria: a zoonotic disease in France? Vaccine, (2009) 27:4196-4200
• BOLT F., CASSIDAY P., TONDELLA ML., DeZOYSA A., EFSTRATIOU A., SING A., ZASADA A., BERNARD K., GUISO N., BADELL E., ROSSO ML., BALDWIN A., DOWSON C. Multilocus sequence typing identifies evidence for recombination and two distinct lineages within Corynebacterium diphtheriae. J. Clin. Microbiol (2010) 48(11) : 4177-4185
• TROST E, OTT L, SCHNEIDER J, SCHRODER J, JAENICKE S, GOESMANN A, HUSEMANN P, STOYE J,ALVES Dorella F, SOUZA ROCHA F, de CASTRO SOARES S, D'AFONSECA V, MIYOSHI A, RUIZ J,SILVA A, AZEVEDO V, BURKOVSKI A, GUISO N, JOIN-LAMBERT OF, KAYAL S, TAUCH A. The complete genome sequence of Corynebacterium pseudotuberculosis FRC41 isolated from a 12-year-old girl with necrotizing lymphadenitis reveals insights into gene-regulatory networks contributing to virulence. (2010) BMC Genomics 11(1):728
• ROUSSEAU C, BELCHIOR E, BROCHE B, BADELL E, GUISO N, LAHARIE I, PATEY O, LEVY-BRUHL D. Diphtheria in the south of France, March 2011. (2011) 16(19): pii=19867 Available online:http://www.eurosurveillance.org/ViewArticle.aspx?ArticleId=19867
• BARRAUD O, BADELL E, DENIS F, GUISO N, PLOY MC. Antimicrobial drug resistance in Corynebacterium diphtheriae mitis (2011) Emerg Infect Dis.Nov;17(11):2078-8017(11):2078-80
• FARFOUR F, BADELL E, ZASADA A, HOTZEL H, TOMASO H, GUILLOT S, GUISO N. Characterization and comparison of invasive Corynebacterium diphtheriae isolates from France and Poland (2012) J. Clin Microbiol. 50(1): 173-175
• FARFOUR E, LETO J, BARRITAULT M, BARBERIS C, MEYER J, DAUPHIN B, LE GUERN A-S, LEFLECHE A, BADELL E, GUISO N, LECLERCQ A, LE MONIER A, LECUIT M, RODRIGUEZ-NAVA V, BERGERON E, RAYMOND J, VIMONT S, CARBONNELLE E, GUET-REVILLET H, LÉCUYER H, BERETTI J-L, VAY C, BERCHE P, FERRONI A, NASSIF X, JOIN-LAMBERT O. Evaluation of the Andromas Matrix-Assisted Laser Desorption Ionization Time of Flight Mass Spectrometry System for Identification of Aerobically growing Gram-Positive Bacilli. (2012) J. Clin. Microbiol. 50(8)2702:2707
• GUISO N. Le nouveau visage de la diphtérie. Revue francophone des Laboratoire(2012)439Bis:34-35
• FARFOUR E, BADELL E, DINU S, GUILLOT S, GUISO N. Microbiological changes and diversity in autochthonous non-toxigenic corynebacterium diphtheria isolated in France. Clin Microbiol Infect(2013) Oct;19(10):980-7
• DINU S, DAMIAN M., BADELL E, DRAGOMIRESCU CS, GUISO N. New diphtheria toxin repressor types in a Romanian collection of Corynebacterium diphtheriae isolates. J. Basic Microbiology(2013). Dec 2.
• SILVA ADO S, BARAUNA RA, DE SA PC, DAS GRACAS DA, CARNEIRO AR, THOUVENIN M, AZEVEDO V, BADELL E, GUISO N, DA SILVA AL, RAMOS RT. Draft Genome Sequence of Corynebacterium ulcerans FRC58, Isolated from the Bronchitic Aspiration of a Patient in France. Genome Announc. (2014) Jan 9;2(1)
• ZASADA AA, FORMINSK K, WOLKOWICZ T, BADELL E, GUISO N. The utility of the PCR melting profile technique for typing Corynebacterium diphtheriae isolates. Lett Appl Microbiol. (2014) Sep;59(3):292-8.
• FARFOUR E, BADELL E, JACQUES NATALI L, DOMMERGUES MA, Blot S, GUISO N, PANGON B, FOUCAUD P. Photo quiz: multiple skin lesions on a 9-year-old boy returning from mali. J Clin Microbiol. (2014) Oct;52(10):3523 and Answer to october 2014 photo quiz. J Clin Microbiol. (2014) Oct;52(10):3832-3.
• VANDENTORREN S, GUISO N, Badell E, BOISRENOULT P, MICAELO M, TROCHE G, LECOULS P,  MOQUET MJ, Patey O, BELCHIOR E. Toxigenic Corynebacterium ulcerans in a fatal human case and her feline contacts, France, March 2014. (2014) 19(38), Available online:http://www.eurosurveillance.org/ViewArticle.aspx?ArticleId=20910