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Document de presse | 2021.05.05
COVID-19: discovery of the mechanisms of short- and long-term anosmia
Loss of smell, or anosmia, is one of the earliest and most commonly reported symptoms of COVID-19. But the mechanisms involved had yet to be clarified. Scientists from the Institut Pasteur, the CNRS, Inserm, Université de Paris and the Paris Public Hospital Network (AP-HP) determined the mechanisms involved in the loss of smell in patients infected with SARS-CoV-2 at different stages of the...
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Document de presse | 2021.05.12
An Asthma Vaccine Effective in Mice
Inserm teams led by Laurent Reber (Infinity, Toulouse) and Pierre Bruhns (Humoral Immunity, Institut Pasteur, Paris) and French company NEOVACS have developed a vaccine that could induce long-term protection against allergic asthma, reducing the severity of its symptoms and thus significantly improving patient quality of life. Their research in animals has been published in the journal Nature...
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Document de presse | 2021.05.21
ART Plus Combination Immunotherapy Expands Natural Killer Cells That Facilitate Control of HIV
Yerkes National Primate Research Center researchers in collaboration with Institut Pasteur have determined a combination immunotherapy of Interleukin-21 (IL-21) and interferon alpha (IFNa) is effective in generating highly functional natural killer (NK) cells that can help control and reduce simian immunodeficiency virus (SIV) in animal models. This finding is key for controlling HIV/AIDS, which...
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News | 2021.05.21
Mitochondrial diseases: a new screening leads to insight on the effect of various genes on DOA
Dominant optic atrophy (DOA) is one of the most common forms of mitochondrial disease. It can be caused by genetic mutations in OPA1 resulting in mitochondrial dysfunction. Researchers from Institut Pasteur and CNRS found ways to study and modulate the effect of genetic mutations in OPA1.Genetic mutations in the gene Optic Atrophy 1 (OPA1) cause a disease named Dominant optic atrophy (DOA). Most...
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Document de presse | 2021.04.23
Professor Stewart Cole appointed Institut Pasteur President for a further two-year term
On Friday April 16, the Institut Pasteur Board of Governors appointed Professor Stewart Cole President for a further two-year term from January 1, 2022 to December 31, 2023.This decision is based on the President's commitment to the development and implementation of the 2019-2023 Strategic Plan, which includes the key priority of tackling infectious diseases, and on his ability to carry out the...
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News | 2021.05.20
Rare case of death following infection by a bat-borne virus related to rabies
Rabies is still responsible for approximately 60,000 deaths in humans each year. The bat-borne virus EBL1a, related to rabies, rarely affects humans, but a case was recently reported in mainland France. The virus was identified thanks to a collaborative effort between the Institut Pasteur and the Limoges, Pitié-Salpêtrière and Necker-Enfants Malades (Paris Public Hospital Network – AP-HP)...
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Fiche maladie | 2022.06.03
Autism
Autism is a neurodevelopmental disorder (NDD). It appears in early childhood (before the age of 36 months) and affects children's developmental areas in different ways and to different degrees. In most cases, its effects impact on autistic individuals' level of independence and social interaction and participation. It is therefore important to diagnose the condition and take action as early as...
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News | 2021.06.01
An imaging and modeling approach to characterize the structure of DNA in human cells
The structure of DNA and chromosomes is a major focus of research, but still holds a number of mysteries. Scientists from the Institut Pasteur and the CNRS have developed a new method for quantifying chromatin loops and observing chromosomes at high resolution.In our cells, DNA is coiled up many times, enabling it to fit into the cell nucleus, which is approximately 200,000 times smaller than the...
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News | 2021.06.03
Signing of a research collaboration agreement between the Institut Pasteur, the Paris Public Hospital Network (AP-HP) and Janssen Biotech, Inc.
The three-year collaboration agreement signed on March 31, 2021 between the Institut Pasteur, the Paris Public Hospital Network (AP-HP) and Janssen Biotech, Inc., the R&D partner of Janssen France, one of the pharmaceutical companies in the Johnson & Johnson group, paves the way for research into the signaling pathways involved in chronic inflammatory rheumatic diseases.One of the aims of...
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News | 2021.05.31
Diphtheria outbreak in Yemen: an epidemiology study
Diphtheria is a severe infection caused in humans by toxigenic strains of Corynebacterium diphtheriae bacteria. If left untreated, it leads to death in 5 to 25% of cases. It generally affects the upper respiratory tracts, causing pseudomembrane formation and sometimes leading to suffocation. The infection can be complicated by systemic symptoms caused by the diphtheria toxin. Scientists from the...
