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Document de presse | 2021.06.22
Drug repurposing to counter COVID-19: antiviral activity may be induced by phospholipidosis
Over the past 16 months and against the backdrop of the COVID-19 health crisis, thousands of drugs have been tested with a view to repurpose them to tackle SARS-CoV-2. Many of these drugs have demonstrated potential antiviral activity (23 compounds including hydroxychloroquine, azithromycin, amiodarone and 4 others tested in clinical trials). Given this high number of potential treatments, the...
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Fiche maladie | 2021.05.11
Parkinson
Parkinson’s disease is a degenerative disorder affecting almost 200,000 people in France. It is the second leading cause of motor disability in adults after stroke and is characterized by the gradual loss of certain neurons in the brain. Although current treatments may alleviate symptoms, they are incapable of slowing disease progression.
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Document de presse | 2021.06.29
Neonatal meningitis: the immaturity of microbiota and epithelial barriers implicated
Meningitis is associated with high mortality and frequently causes severe sequelae. Newborn infants are particularly susceptible to this type of infection; they develop meningitis 30 times more often than the general population. Group B streptococcus (GBS) bacteria are the most common cause of neonatal meningitis, but they are rarely responsible for disease in adults. Scientists from the Institut...
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Document de presse | 2021.07.01
Modelling study of benefits and risks associated with the COVID-19 vaccine Vaxzevria
On April 7, 2021, the European Medical Agency (EMA) concluded that thrombosis in combination with thrombocytopenia has been identified as a likely adverse event following vaccination with the COVID-19 vaccine Vaxzevria. Researchers from the Mathematical Modelling of Infectious Diseases Unit at the Institut Pasteur used a mathematical model to assess its benefits and risks in...
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Document de presse | 2021.06.30
The Université de Paris – the Institut Pasteur Association: A world-class partnership in research and teaching in the field of health biology
Christine Clerici, President of Université de Paris, and Stewart Cole, Director General of the Institut Pasteur, have formalised the cooperation between their institutions in pursuit of a concerted and shared scientific strategy. The two institutions aim to co-develop and strengthen areas of mutual interest in basic and translational research as well as in teaching. The fields of biology and...
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Document de presse | 2020.04.28
Introduction and initial circulation of SARS-CoV-2 in France
Following the emergence of COVID-19 disease in Wuhan in December 2019, syndromic surveillance was implemented in France from January 10, 2020. Two weeks later, the first three imported cases of COVID-19 in Europe were diagnosed in France.The National Reference Center for Respiratory Viruses has been contributing to the genomic surveillance of SARS-CoV-2 for northern France since the first cases...
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Document de presse | 2021.06.24
Dengue: discovery of a new indicator for predicting disease severity
Dengue virus causes an average of 500,000 hemorrhagic cases annually, posing a threat to over 2.5 billion people throughout the world every year. Scientists at the Institut Pasteur du Cambodge and the Rockefeller University working in collaboration with the Institut Pasteur (CNRS joint laboratory) have revealed that the absence of a sugar known as fucose forming the structure of anti-dengue...
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News | 2021.07.09
The Institut Pasteur International Network is evolving and becoming the Pasteur Network
A new system of governance is being introduced for the Institut Pasteur International Network and its 33 members, which since 2011 have been part of the Pasteur International Network association, which was chaired by the Institut Pasteur President Stewart Cole. Ten years on, the Network is adopting a more participatory, balanced mode of governance and a more structured business model. The...
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News | 2021.07.15
BCG vaccine: the first tuberculosis vaccination took place a century ago
July 2021 marks the hundredth anniversary of the first vaccination of an infant with the BCG vaccine. Although tuberculosis is still one of the ten leading causes of mortality worldwide, this vaccine, developed at the Institut Pasteur, led to a steep reduction in the number of cases. We take a look back at how the vaccine was discovered.Albert Calmette arrived in Lille in 1897 as director of the...
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News | 2021.07.19
COVID-19: interaction identified between SARS-CoV-2 and unusual RNA structures in human cells
Replication of SARS-CoV-2, the virus responsible for COVID-19, depends on a series of interactions between viral proteins and different cellular partners such as nucleic acids (DNA or RNA). Characterizing these interactions is crucial to elucidate the process of viral replication and identify new drugs for treating COVID-19.An interdisciplinary consortium of scientists from the Institut Pasteur,...
