Research

The Institut Pasteur is an internationally renowned center for biomedical research that stands out in many disciplines. By deciphering the fundamental mechanisms of living organisms, its researchers contribute to the advancement of knowledge that leads to cutting-edge medical applications, ultimately improving public health.

Research at the Institut Pasteur is based on four key strengths:

  • research conducted at all levels of life, from molecules to individuals and populations;
  • multidisciplinary strategies, focusing on molecular and cellular approaches as well as bioinformatics, biophysics, chemistry and nanotechnologies;
  • unique technological facilities, including the most powerful microscope in the world (Titan);
  • an international network of 33 institutes, (the only one of its kind in the world), which is present on every continent.

Combining these resources is essential to responding to the major public health challenges of today, for example antibiotic resistance, the impact of microbiota (formerly called gut flora) on our health, promoting healthy aging, etc. Institut Pasteur is engaged on these fronts and its discoveries improve prevention, diagnosis and treatment of infectious diseases (Ebola, malaria, AIDS, tuberculosis, Zika, etc.), neurodegenerative diseases (Alzheimer's, Parkinson's, etc.), cancers (uterine, stomach, etc.), autism, etc.

Thanks to strong interdisciplinary and international capacities, at the Institut Pasteur, diverse research fields and expertise synergize to generate major breakthroughs in biomedicine. In this way, an understanding of the fundamental mechanisms of cell motility benefits cancer researchers studying metastasis dissemination. Similarly, characterization of the genetic and environmental factors that influence our immune response, whether through infection or vaccination, paves the way for personalized medicine. 

These examples show the vital role of Institut Pasteur’s fundamental research and its impact on clinical research to the benefit of patients. This positive influence on public health is also seen in Institut Pasteur’s educational mission, a commitment to share knowledge with future generations of researchers and doctors.  

Lluis Quintana-Murci - Institut Pasteur
 

Lluis Quintana-Murci

Scientific Director

at the Institut Pasteur

Even if our ultimate aim is to improve the treatment and prevention of today's diseases and future diseases, to do so we first need to dissect how humans and other organisms, microbes in particular, function. This is precisely the Institut Pasteur’s strength — bringing together researchers from different disciplines in fundamental research, using unique technological facilities, to understand physiological and pathological processes taking place in living organisms. It is only by using such multidisciplinary and integrative approaches that we can ultimately improve human health.

 

 

Departments

Département de Biologie cellulaire et infection - Institut Pasteur

Cell Biology and Infection

Shedding light on the intricate workings of microbes and cells is the focus of research conducted in this department.

Département de Biologie du développement et cellules souches - Institut Pasteur

Developmental and Stem Cell Biology

How do cells acquire their identity? How are organs formed? Little is known about the mechanisms behind the “development” of animals, including human beings.

Département Génomes et génétique - Institut Pasteur

Genomes and Genetics

Exploring the genomes of bacteria, yeast, insect vectors and ultimately humans.

Département d'immunologie - Institut Pasteur

Immunology

The complexity of the immune system is a never-ending source of fascination for scientists.

Département Infections et épidémiologie - Institut Pasteur

Infection and Epidemiology

Studying infectious diseases and tackling the emergence of new pathogenic agents.

Département de Microbiologie - Institut Pasteur

Microbiology

Bacteria have always been important research models at the Institut Pasteur.

Département de Mycologie - Institut Pasteur

Mycology

Mycoses have been a major public health issue since the early 1980s.

Département de Neurosciences - Institut Pasteur

Neuroscience

The nervous system has yet to reveal all its secrets.

Département Parasites et insectes vecteurs - Institut Pasteur

Parasites and Insect Vectors

Parasitic diseases are all too often neglected. However, they affect close to 3 billion people in the world.

Département de Biologie structurale et chimie - Institut Pasteur

Structural Biology and Chemistry

Observing life at atomic level because chemistry is the motor of life.

Département de Virologie - Institut Pasteur

Virology

Fighting viral infections that affect human health.

Transversal research centers

2014 saw the creation of 4 inter-disciplinary research centers which all help to stimulate
collaborations and synergy between initiatives within the campus and international network.

CENTER FOR GLOBAL HEALTH - Institut Pasteur

Center for Global Health (CGH)

Director of the CGH:

Arnaud Fontanet

Facilitating and raising the profile of Institut Pasteur projects that tackle global health threats.

CENTRE D’INNOVATION ET RECHERCHE TECHNOLOGIQUE - Institut Pasteur

Center for Innovation and Technological Research (Citech)

Director of the Citech:

Jean-Christophe Olivo-Marin

A technological hub to advance innovation and research.

CENTRE DE RECHERCHE TRANSLATIONNELLE - Institut Pasteur

Center for Translational Science
(CRT)

Director of the CRT:

Stanislas Pol

Facilitating new biomedical projects and contributing to the advancement of medicine.

CENTRE DE BIOINFORMATIQUE, BIOSTATISTIQUE ET BIOLOGIE INTÉGRATIVE - Institut Pasteur

Center of Bioinformatics, Biostatistics and Integrative Biology (C3BI)

Director of the C3BI:

Olivier Gascuel

An international reference center for processing, analyzing and modeling biological data.

 

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