1. News | 2021.03.11

   2019-2023 Strategic Plan: Two new projects to boost the Institut Pasteur Innovation Accelerator

   Two projects have been accepted into the Institut Pasteur Innovation Accelerator, an initiative to improve the development potential of the Institut Pasteur's research: a highly automated technological system involving bioassays and a partnership based on a French startup studio. The Institut Pasteur will be setting up the project Pfbioassays [in French] (Thierry Rose and Sébastien...

2. News | 2021.03.24

   World Tuberculosis Day: ERA4TB accelerating the development of new treatment regimens

   ERA4TB (the European Regimen Accelerator for Tuberculosis) is a 6-year public-private partnership with a total budget of over €200M that began in 2020 with the goal of accelerating the development of new treatment regimens for tuberculosis (TB). As part of the Innovative Medicines Initiative, ERA4TB brings together experts from academia and pharma, led by Stewart Cole (Institut Pasteur) and David...

3. News | 2021.03.22

   Cell division: BST2, the common feature between viral infections and midbodies

   The human body is made up of tens of thousands of billions of cells, all originating from the division of one parent cell into two daughter cells. Scientists from the Institut Pasteur set out to investigate midbodies, which are key cell division structures, and they identified the role of BST2, a restriction factor involved in viral infections.In order to divide, cells start by making identical...

4. Document de presse | 2021.03.09

   ComCor: Study examining the sociodemographic, behavioral and practical factors associated with SARS-CoV-2 infection

   The ComCor study is conducted by the Institut Pasteur in partnership with the French National Health Insurance Fund (CNAM), Ipsos and Santé publique France.Intermediate analysis, on March 1, 2021The ComCor study, which currently covers the period from October 1, 2020 to January 31, 2021, includes 77,208 participants with acute SARS-CoV-2 infection, excluding healthcare workers (8.2% of those...

5. Document de presse | 2021.03.26

   COVID-19: analysis of the sensitivity of the UK (B.1.1.7) and South African (B.1.351) variants to SARS-CoV-2 neutralizing antibodies

   The B.1.1.7 and B.1.351 variants of SARS-CoV-2 were first detected in the UK and South Africa respectively, and have since spread to many other countries. Scientists from the Institut Pasteur joined forces with Orléans Regional Hospital, Tours University Hospital, Créteil Intercommunal Hospital, Strasbourg University Hospital and Georges Pompidou European Hospital to study the sensitivity of...

6. Document de presse | 2021.03.23

   SARS-CoV-2 variants of interest can infect mice: host range extended

   SARS-CoV-2, the virus responsible for COVID-19, is capable of infecting some species, while others are naturally resistant to it. This determines the "host range" of the virus. The SARS-CoV-2 host range includes humans, non-human primates, hamsters, mink and cats. Since the start of the pandemic, mice and rats had proven to be resistant to SARS-CoV-2, because their ACE2 receptor, which allows the...

7. News | 2021.03.30

   Cancer: CAR T cell function scrutinized to improve immunotherapy

   Immunotherapy, or the notion of "retraining" patients' immune systems, constitutes a major step forward in the fight against cancer. Although the results of CAR T cell therapy are very positive, its efficacy is still difficult to predict. Research by scientists at the Institut Pasteur has improved our understanding of how these cells function. One immunotherapy strategy involves genetically...

8. Document de presse | 2021.04.06

   Light shed on the coordination of neural stem cell activation

   In all adult vertebrates, neural stem cells can be recruited to produce new neurons in the brain. However, little is known about these so-called "activation" processes. Scientists at the Institut Pasteur, CNRS, and Tel Aviv University working in collaboration with the École Polytechnique and INRAE have successfully performed 3D visualization and spatial and temporal distribution analysis of...

9. News | 2021.03.30

   Mobilization of the Institut Pasteur International Network to manage the COVID-19 outbreak: case study of support provided to the Institut Pasteur de Bangui

   Since the beginning of the COVID-19 pandemic, and increasingly rapidly thereafter, the Institut Pasteur International Network has drawn heavily on all its expertise and resources to tackle this emerging virus and its consequences, particularly through its support of institutes based in low-income countries. All Network member institutes have been identified by their health authorities as...

10. Document de presse | 2021.04.14

    Genetic admixture in the South Pacific: from Denisovans to the human immune response

    Describing the genetic diversity of human populations is essential to improve our understanding of human diseases and their geographical distribution. However, the vast majority of genetic studies have been focused on populations of European ancestry, which represent only 16% of the global population. Scientists at the Institut Pasteur, Collège de France, and CNRS have looked at understudied...

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