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Document de presse | 2017.11.28
Right/left: the heart of the matter
1% of all newborns – approximately 8,000 babies a year in France – are affected by a heart defect. 15% of these defects can be linked to a known genetic cause, but many remain unexplained. Defects affecting the alignment of cardiac chambers represent approximately 20% of heart defects in infants. A team of scientists from the Institut Pasteur and the UMR-1163 joint research unit at the Imagine...
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News | 2020.07.03
ARIAweb: a server for automated NMR structure calculation
The ARIA software suite developed at Institut Pasteur automates the analysis of NMR data to calculate three-dimensional structures of macromolecules. To improve the user experience for ARIA and provide a larger and easier access, tructural bioinformatics Unit has created the ARIAweb server, providing an online service for such computationally intensive calculations and offering a dedicated...
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News | 2021.05.06
Creation of the startup SPIKIMM to develop monoclonal antibodies as an innovative treatment for Covid-19
The Institut Pasteur has recently signed an exclusive worldwide license agreement with the new biotech start-up SpikImm SAS, created by Truffle Capital, for the development of anti-SARS-CoV-2 (Covid-19) monoclonal antibodies for therapeutic and diagnostic use.Monoclonal antibody therapy is one of the most innovative ways currently available to treat Covid-19 patients and prevent severe forms of...
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Portrait | 2018.07.02
3D research according to Albane Imbert, an engineer at the Institut Pasteur
Albane's digital fabrication laboratory, or Fab Lab for those in the know, can be found in the Institut Pasteur's newest building. This is the place where tools for innovative technology research projects are developed. Back in 2016, when Albane was creating smart objects for industry, the Institut Pasteur asked her if she would be interested in developing a prototyping platform for new...
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Fiche maladie | 2015.10.06
Leishmaniasis
Leishmaniasis is a parasitic disease that causes severely debilitating cutaneous or visceral lesions, which can be fatal if left untreated. The plural form "leishmaniases" is sometimes used, as the disease is actually a group of diseases caused by different parasites of the genus Leishmania, transmitted by the bites of sandflies. These parasitic diseases are considered emerging neglected diseases...
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Document de presse | 2021.10.11
SARS-CoV-2 Alpha, Beta and Delta variants display enhanced viral fusion properties compared to ancestral strains
In a new study published in EMBO Journal on October 2, 2021, scientists from the Institut Pasteur, the CNRS, Université de Paris, the Vaccine Research Institute and Sorbonne University examined the fusion mechanisms of different SARS-CoV-2 variants: Alpha (initially identified in the United Kingdom), Beta (initially identified in South Africa) and Delta (initially identified in India). The Delta...
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News | 2022.07.22
Cryptococcal meningitis: a new effective treatment with fewer side effects
A large-scale clinical trial has demonstrated the efficacy of a new therapeutic protocol to treat cryptococcal meningitis associated with HIV infection and shown that it leads to fewer adverse effects.
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Document de presse | 2010.12.01
Identification of the 3D structure of chikungunya virus surface proteins
Researchers at the Institut Pasteur and CNRS, in collaboration with the Synchrotron SOLEIL, have solved the three-dimensional atomic structure of the glycoproteins that envelop the chikungunya virus. This discovery helps to understand how this protein complex is activated in order for the virus to invade target cells. Activation is a key stage in the viral life cycle and understanding its...
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Fiche maladie | 2015.10.06
Whooping cough (pertussis)
Whooping cough, long thought of as a childhood illness, can be severe at any age. This bacterial infection is particularly dangerous, and sometimes even fatal, for unvaccinated or partially vaccinated infants and at-risk individuals such as pregnant women and elderly people.
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Document de presse | 2017.08.31
Gut microbiota of mosquito larvae has an impact on adult insect’s ability to transmit human pathogens
Researchers from the Institut Pasteur and CNRS, in collaboration with scientific teams from IRD, University Claude Bernard Lyon 1*, and CIRMF in Gabon, have demonstrated that differential bacterial exposure during the development of mosquito larvae (Aedes aegypti) can have “carry-over” effects on adult traits related to an insect’s ability to be a successful vector of arboviruses. These results...