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Document de presse | 2006.12.10
Inflammatory intestinal diseases: the lessons of Shigella
The bacterium Shigella flexneri, responsible for shigellosis, or bacillary dysentery, acts by invading intestinal cells. Researchers from the Institut Pasteur associated with Inserm have now shown how this bacterium modulates the inflammatory response at the cell level to ensure its survival. By deciphering the mechanisms at work, they are pointing out to possibly new therapeutic targets, opening...
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Document de presse | 2006.08.31
Malaria Parasite: The Trojan Horse strategy revealed
A team from the Pasteur Institute has just uncovered a subtle mechanism used by the parasite that is responsible for malaria to escape from the immune system during a crucial stage of its cycle inside its mammalian host. This has been made possible thanks to in vivo imaging techniques that make it possible to follow the parasite in real time inside the host organism. This discovery - published in...
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News | 2018.06.08
Meningococcal infection: bacterial aggregates form a thick honey-like liquid that flows through blood vessels
The Inserm team led by Guillaume Duménil at the Institut Pasteur, in collaboration with several teams of physicists, has unraveled a key stage in infection by Neisseria meningitidis, a human pathogen responsible for meningitis in infants and young adults. Bacterial aggregates in blood vessels appear to facilitate the progression of the disease. Even if treatment is administered rapidly, the...
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Document de presse | 2018.10.04
Smoking cessation: a genetic mutation involved in relapse
Why is it so difficult to stop smoking? Why do some people relapse months after giving up? Scientists from the Institut Pasteur and the CNRS, in collaboration with Sorbonne University and Inserm, have demonstrated that a genetic mutation already known to be involved in sensitivity to nicotine also plays a role in relapse behavior after cessation in rats. The findings were published in the journal...
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Article | 2019.04.24
Dr Amy Kristine Bei to head a new 4-year research group on malaria in Dakar
A new 4-year research group (G4) is being set-up at the Institut Pasteur de Dakar and started in early February following the agreement signed between the Institut Pasteur and AUF (Agence universitaire de la francophonie) on 31 January 2019, in collaboration with the Yale School of Public Health. Entitled « Malaria Experimental Genetic Approaches and Vaccines », it will be led by...
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Document de presse | 2020.05.26
MV-SARS-CoV-2 vaccine candidate: a new partnership between Institut Pasteur, CEPI, Thémis and MSD
Institut Pasteur announces recent advances in the development of one of its candidate vaccines, MV-SARS-CoV-2, using the measles vector, as part of a renewed partnership with CEPI and the companies Thémis and MSD.With over 100 vaccine projects in development worldwide, the development of a vaccine against SARS CoV-2 infection remains a challenge, with many scientific uncertainties ahead. The...
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News | 2020.07.27
"Mental anchorpoints" used by musicians to identify pitch
How do we recognize pitch? An observational study carried out by the Institut Pasteur with the support of the French Society of Authors, Composers and Publishers of Music (SACEM), involving interviews with nearly 70 musicians (music students and professionals), addressed this question and found some initial answers. Musicians recognize pitch by drawing on three mental sensory modalities (auditory...
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Document de presse | 2020.09.21
Cocaine addiction : impact of genetic mutations elucidated
Cocaine addiction is a chronic disorder with a high rate of relapse for which no effective treatment is currently available. Scientists from the Institut Pasteur, the CNRS, Inserm and the Paris Public Hospital Network (AP-HP) recently demonstrated that two gene mutations involved in the conformation of nicotinic receptors in the brain appear to play a role in various aspects of cocaine addiction...
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Document de presse | 2023.12.14
Working together against deadly Marburg virus
International research consortium receives highly endowed Horizon Europe funding for the development of vaccines against Marburg viruses.The multidisciplinary European consortium MARVAX will receive 7.4 million euros over the next four years for the research and development of vaccines against Marburg viruses. Researchers from France, Spain and Germany will develop novel vaccine candidates, which...
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News | 2021.11.24
During DNA repair, a protein regulates homology search by reorganizing the genome
Homologous recombination is one of the major pathways for repairing broken DNA. A study by scientists from the Institut Pasteur and ENS Lyon shows how a protein known as cohesin reorganizes the genome into loops to enable this process.