-
News | 2022.07.22
Cryptococcal meningitis: a new effective treatment with fewer side effects
A large-scale clinical trial has demonstrated the efficacy of a new therapeutic protocol to treat cryptococcal meningitis associated with HIV infection and shown that it leads to fewer adverse effects.
-
Article | 2016.12.20
Parasites and Insect Vectors
Parasitic diseases are all too often neglected. However, they affect close to 3 billion people in the world. Biomedical research is therefore at the heart of global public health challenges, and the mission of the scientists in this department is to tackle the ongoing need for better prevention, control and treatment of these parasitic diseases.
-
Document de presse | 2010.12.01
Identification of the 3D structure of chikungunya virus surface proteins
Researchers at the Institut Pasteur and CNRS, in collaboration with the Synchrotron SOLEIL, have solved the three-dimensional atomic structure of the glycoproteins that envelop the chikungunya virus. This discovery helps to understand how this protein complex is activated in order for the virus to invade target cells. Activation is a key stage in the viral life cycle and understanding its...
-
Fiche maladie | 2015.10.06
Whooping cough (pertussis)
Whooping cough, long thought of as a childhood illness, can be severe at any age. This bacterial infection is particularly dangerous, and sometimes even fatal, for unvaccinated or partially vaccinated infants and at-risk individuals such as pregnant women and elderly people.
-
Document de presse | 2017.08.31
Gut microbiota of mosquito larvae has an impact on adult insect’s ability to transmit human pathogens
Researchers from the Institut Pasteur and CNRS, in collaboration with scientific teams from IRD, University Claude Bernard Lyon 1*, and CIRMF in Gabon, have demonstrated that differential bacterial exposure during the development of mosquito larvae (Aedes aegypti) can have “carry-over” effects on adult traits related to an insect’s ability to be a successful vector of arboviruses. These results...
-
Document de presse | 2019.12.16
A new breakthrough in developing effective antimalarial drugs
Parasites in the genus Plasmodium, which cause malaria, are transmitted to humans through bites from infected mosquitoes. The parasites manage to acclimatize to these two completely different hosts because the plasticity of their genome enables them to adapt as necessary. Scientists at the Institut Pasteur and the CNRS decided to investigate the epigenetic mechanisms behind this plasticity, in...
-
News | 2023.04.03
Brain Awareness Week: the amazing learning abilities of babies
Could there have been any doubt that babies can recognize their mother even before they are born, that they learn to speak based on the sound of the voice and express an unquenchable curiosity for faces? Four scientists spoke at the conference "What do babies think about?" organized at the Institut Pasteur for Brain Awareness Week 2023. Their presentations taught us more about the surprising...
-
Document de presse | 2016.04.11
Malaria: a new route of access to the heart of the parasite
Scientists have just identified an Achilles heel in the parasite that causes malaria, by showing that its optimum development is dependent on its ability to expropriate RNA molecules in infected cells – a host-pathogen interaction that had never previously been observed. Although the precise function of this deviation remains mysterious, these findings open new perspectives for the targeted...
-
Document de presse | 2016.07.07
Phage therapy: fundamental action mechanisms revealed
In an article published in PLoS Genetics on July 5, scientists from the Institut Pasteur and the Belgian-based Université catholique de Louvain identify for the first time the genetic and metabolic mechanisms underpinning the therapeutic action of a bacteriophage known for its therapeutic potential. Given the worrying rise in bacterial resistance to antibiotics and the difficulties in developing...
-
Document de presse | 2016.07.18
Malaria: a genetically attenuated parasite induces an effective, long-lasting immune response
With nearly 3.2 billion people currently at risk of contracting malaria, scientists from the Institut Pasteur, the CNRS and Inserm have experimentally developed a live, genetically attenuated vaccine for Plasmodium, the parasite responsible for the disease. By identifying and deleting one of the parasite's genes, the scientists enabled it to induce an effective, long-lasting immune response...