1. News | 2021.07.23

   A new method for identifying differences between bacterial strains from the same environment

   In recent years, the scientific community has realized that different bacterial strains can play very different roles in an environment. The identification of these strains and their genomes is important for both basic research and human health. Scientists from the Institut Pasteur have developed a method to identify the genomes of different strains in the same environment.For any given type of...

2. News | 2021.08.19

   Monkeypox in Central African Republic: genomic history suggests multiple introductions from rainforest animal reservoirs

   Monkeypox is an emerging and neglected infectious disease caused by the Monkeypox virus (MPXV). The disease has a similar clinical presentation to smallpox, with a maculopapular rash (a skin rash characterized by small spots), especially on the palms of the hands and the soles of the feet.Human transmission of the MPXV virus, responsible for monkeypox, occurs either through direct contact with...

3. News | 2021.09.02

   Use of bacteriophages for preventing the most common foodborne infection, salmonellosis

   Salmonellosis caused by the Salmonella bacterium is the most common example of foodborne infections, which remain a global public health problem, with over 600 million infections and 400,000 deaths every year. Use of antibiotics during outbreaks entails a risk of resistance. Scientists at the Institut Pasteur have demonstrated that bacteriophages may be used as a prophylactic treatment.The...

4. News | 2021.09.09

   SPKM001, a promising anti-SARS-CoV-2 monoclonal antibody, is being developed by the Institut Pasteur and SpikImm

   Following encouraging initial results, which will be published shortly, the Institut Pasteur and SpikImm announce the development of the antibody SPKM001.Paris, September 9, 2021SPKM001 is a high affinity human monoclonal antibody which targets the receptor-binding site (RBD) on the Spike protein of the original SARS-CoV-2 strain and its variants.Initial preclinical results tend to show that this...

5. News | 2020.03.20

   Importance of cohesin to yeasts' 3D chromosome structure

   The 3D organization of chromosomes plays a role in many biological processes. The ring formed by the cohesin complex is an important regulator of this organization, especially in mammals where it establishes chromatin loops during interphase. Researchers from the Spatial Regulation of Genomes Unit and the CNRS show that such loops structure yeast chromosomes in metaphase and characterize the...

6. News | 2020.05.05

   Activation of macrophages, key agents in immune response

   Known to kill bacteria, can antibiotics also interfere with our immune system? Researchers at the Pasteur Institute have discovered that a new molecule, used to treat tuberculosis that is multi-resistant to antibiotics, activates the defence functions of macrophages, important players in innate immunity. These cells then became able to fight against bacterial infections, which were normally...

7. News | 2020.02.05

   Meningococci: an example of genomics used as an epidemiological tool

   By examining vaccine coverage of invasive meningococcal infections in conjunction with genomic and pathophysiological analyses, it was possible to detect a new genotype in meningococcal serogroup W and characterize the emergence of the resulting bacterial strain. This combined approach has been a useful decision-making tool in implementing measures to control invasive meningococcal infections in...

8. News | 2021.09.14

   The "Springboard" award for bilateral research cooperation – Africa recognizes two Pasteurians

   Africa2020 Season, launched in December 2020 by French President Emmanuel Macron and ended in summer 2021, has taken place throughout France, involving both mainland France and French overseas territories. In this context, two Pasteurians, Aïda Bouratbine at the Institut Pasteur de Tunis and Gérald Späth at the Institut Pasteur have been rewarded.  The aim of Africa2020 Season is to shine a...

9. Document de presse | 2022.02.16

   SARS-CoV-2-related viruses capable of infecting human cells discovered in bats in northern Laos

   Since the emergence of SARS-CoV-2, several animal species have been studied to identify potential reservoirs and/or intermediate hosts of the virus. Scientists from the Institut Pasteur du Laos and the National University of Laos recently set out to shed light on the evolution of SARS-CoV-2 and explore the potential presence of SARS-CoV-2-related coronaviruses in the natural environment by...

10. Article | 2021.09.24

    Program analyzing the spread of the SARS-CoV-2 virus in high and low incidence areas of COVID-19 in Senegal

    Thanks to the support provided by the Fondation SUEZ, sero-epidemiological studies were launched by the Dakar Pasteur Institute in July 2020, as part of the fight against the SARS-CoV-19 pandemic. Thesse comparative studies on the prevalence of anti-SARS-COV-2 antibodies were conducted to better identify the risk factors associated with the spread of SARS-CoV-2 virus in populations resideing in...

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