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News | 2020.11.26
Urinary tract infections: the mechanisms behind the lack of immune memory in many patients
Urinary tract infections (UTI) are a group of infectious diseases that predominantly impact healthy adult women, although they can also cause serious disease in men. They are the second most prevalent infection after respiratory infections*. The immune response to UTI is still not well-understood, and a better understanding could help lessen the use of antibiotics for this common infection....
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Fiche maladie | 2015.10.06
Group A and B Streptococcus
Infections with group A and B Streptococcus (respectively Streptococcus pyogenes and Streptococcus agalactiae) are frequent. The two bacteria are part of the commensal flora; they are opportunistic pathogens and only cause symptoms in certain conditions or in people at risk. Group A Streptococcus (also known as GAS or Strep A) is responsible for several benign infections but can also cause...
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News | 2022.08.24
ILC3s: "gatekeeper" cells for intestinal immunity
The intestinal mucosa is a key site for interaction and exchange with the external environment. It is therefore under constant surveillance from the immune system. Using an animal model, scientists from the Institut Pasteur and Inserm discovered how a set of cells involved in innate immunity – group 3 innate lymphoid cells – help monitor and maintain this barrier.Our digestive tract contains...
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Document de presse | 2024.05.28
AFROSCREEN: a key network for genomic surveillance in Sub-Saharan Africa
Three years after its launch, AFROSCREEN meets all its objectives, developing effective genomic surveillance to tackle epidemics in sub-Saharan Africa The AFROSCREEN project, financed to the tune of €10 million by Agence Française de Développement (AFD), has been working since 2021 to set up or strengthen sequencing platforms and build an operational network for monitoring emerging...
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News | 2024.07.25
Paris 2024: Olinda Alegria-Prévot gearing up for the “Marathon for all”
Throughout this special Paris Games, we are pleased to present some of the Institut Pasteur staff who are playing a special role in this global event – whether in their capacity as an Institut Pasteur staff member, a volunteer or a sports person. We hope that these profiles will showcase the fantastic diversity of the Institut Pasteur community. This week, we want to shine a light on Olinda...
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Article | 2019.02.22
PPU-Oxford Program
"Chimie Biologique"Linking Chemistry and Microbiology to Fight Human Diseases
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News | 2019.09.27
Rabies: a shorter, cheaper vaccination schedule following a suspected rabid dog bite
A study by teams from the Institut Pasteur du Cambodge and the Institut Pasteur in Paris confirms the efficacy of the new post-exposure rabies vaccination schedule developed in the Institut Pasteur International Network and adopted by the World Health Organization (WHO). Since 2018, WHO has recommended post-exposure vaccination for rabies, immediately after a bite by a suspected rabid...
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Document de presse | 2021.01.19
COVID-19: a lentiviral vaccine candidate for intranasal administration provides sterilizing protection in animal models
Scientists from the Institut Pasteur-TheraVectys Joint Laboratory recently published in Cell Host & Microbe1 the results of tests, in two preclinical models, of a COVID-19 vaccine candidate using a lentiviral vector administered by nasal route. Their study demonstrates that the vaccine candidate induces antibody response with strong neutralizing activity against SARS-CoV-2, as well as...
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Document de presse | 2020.10.16
Team of international scientists identify common vulnerabilities across SARS-CoV-2, SARS-CoV-1 and MERS coronaviruses
Driven by Molecular Insights, Massive Analysis of Medical Records from ~740,000 SARS-CoV-2 Patients Reveal Treatment Regimens for Current, and Potential Future, Viral Pandemics. Published on October 15, 2020, in Science. In a study published online in Science, an international team of almost 200 researchers from 14 leading institutions in six countries, including France with the...
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News | 2022.07.01
Monitoring and early warning: Pasteur Center in Cameroon plays an active role in the response to SARS-CoV-2 virus
As a first-line laboratory in the event of a health emergency, the Pasteur Center in Cameroon was naturally designated as a COVID-19 reference laboratory by the Cameroon health authorities in 2020. How did the Pasteur Center in Cameroon organize its response to this emerging novel virus at national level throughout the epidemic, and how is it monitoring the virus today?At the beginning of the...