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News | 2018.10.30
Zika virus in the Pacific : the influence of the geographical context on an outbreak’s emergence
Zika virus (ZIKV) is a flavivirus transmitted to humans by Aedes mosquitoes. ZIKV is divided into two phylogenetic lineages: African and Asian. In New Caledonia, the complex interactions between humans, mosquitoes and the virus led to a important outbreak in 2014.In 2013, the Zika virus emerged in French Polynesia and more than 1,500 cases were identified the following year in New Caledonia....
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Document de presse | 2021.01.19
COVID-19: a lentiviral vaccine candidate for intranasal administration provides sterilizing protection in animal models
Scientists from the Institut Pasteur-TheraVectys Joint Laboratory recently published in Cell Host & Microbe1 the results of tests, in two preclinical models, of a COVID-19 vaccine candidate using a lentiviral vector administered by nasal route. Their study demonstrates that the vaccine candidate induces antibody response with strong neutralizing activity against SARS-CoV-2, as well as...
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Document de presse | 2020.10.16
Team of international scientists identify common vulnerabilities across SARS-CoV-2, SARS-CoV-1 and MERS coronaviruses
Driven by Molecular Insights, Massive Analysis of Medical Records from ~740,000 SARS-CoV-2 Patients Reveal Treatment Regimens for Current, and Potential Future, Viral Pandemics. Published on October 15, 2020, in Science. In a study published online in Science, an international team of almost 200 researchers from 14 leading institutions in six countries, including France with the...
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News | 2019.09.27
Rabies: a shorter, cheaper vaccination schedule following a suspected rabid dog bite
A study by teams from the Institut Pasteur du Cambodge and the Institut Pasteur in Paris confirms the efficacy of the new post-exposure rabies vaccination schedule developed in the Institut Pasteur International Network and adopted by the World Health Organization (WHO). Since 2018, WHO has recommended post-exposure vaccination for rabies, immediately after a bite by a suspected rabid...
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News | 2022.07.01
Monitoring and early warning: Pasteur Center in Cameroon plays an active role in the response to SARS-CoV-2 virus
As a first-line laboratory in the event of a health emergency, the Pasteur Center in Cameroon was naturally designated as a COVID-19 reference laboratory by the Cameroon health authorities in 2020. How did the Pasteur Center in Cameroon organize its response to this emerging novel virus at national level throughout the epidemic, and how is it monitoring the virus today?At the beginning of the...
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Document de presse | 2014.06.11
Predicting mutations that lead to epidemics
Using the 2005-2006 chikungunya virus epidemic that occurred in the Indian Ocean islands as a study model, researchers at the Pasteur Institute have succeeded in developing an approach that can predict the virus mutations most likely to emerge in the short-term, with strong epidemic potential. This work has strong implications for improving surveillance of ongoing epidemics and the potential to...
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Document de presse | 2013.03.17
Buruli Ulcer: Mechanism Behind Tissue Erosion Revealed
Scientists at the Pasteur Institute in Paris and the CNRS (French National Center for Scientific Research), in collaboration with the Universities of Basel (Switzerland) and Cambridge (UK) have identified the mechanism underlying the formation of Buruli ulcers caused by the bacterium Mycobacterium ulcerans. Their discovery opens avenues for the development of novel therapeutic approaches for...
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Document de presse | 2012.01.22
Launching of the Institut Pasteur in Laos
Today, Monday January 23, 2012, in Vientiane the launch of the Institut Pasteur in Laos was officiated by the Lao Minister of Public Health, professor Som Ock Kingsadat and the President of the Institut Pasteur in Paris, professor Alice Dautry. This is the Institut Pasteur International Network’s 32nd institute. The new research center for infectious and parasitic diseases aims to reduce...
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Document de presse | 2007.02.21
Aquatic Predator Insect Saliva May Protect Against Buruli Ulcer
Buruli ulcer is a necrotizing skin disease that is very disabling, caused by bacteria that inhabit aquatic environment. It is rife in several regions of the world and is developing at a disturbing rate in West Africa. Researchers at the Institut Pasteur and Inserm, working together with university and institute teams from the Institut Pasteur International Network, recently proved that the...
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Document de presse | 2005.04.13
The art of camouflaging the parasite responsible for malaria
Researchers from the Institut Pasteur and the CNRS have brought to light the unique mechanisms that allow the parasite responsible for malaria to fool the immune system of those it infects. In collaboration with researchers from the Walter and Eliza Hall Institute of Medical Research of Melbourne, they showed in two articles published in Cell that the parasite is capable of changing the...