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News | 2018.06.15
In remembrance of Dr François Rouet
Our colleague and friend François Rouet passed away on June 13, 2018 at the age of 53 following a long illness. The Institut Pasteur International Network wishes to pay tribute to this passionate scientist and public health man who has dedicated his career to improving the care of patients in the most disadvantaged countries.Trained pharmacist, François performs his national service in Cameroon...
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News | 2020.04.15
COVID-19 - The Bioinformatics and Biostatistics Hub on the front line
Like many other research teams at the Institut Pasteur, the Bioinformatics and Biostatistics Hub is engaged in fighting against the COVID-19 pandemic by participating in the curation of GISAID data (Global Initiative on Sharing All Influenza Data). The Hub is the service division of the Computational Biology Department, and is composed of 50 experts in biostatistics and bioinformatics.At the end...
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News | 2020.11.09
Leptospirosis: elucidation of a new gene regulation mechanism based on DNA modification
Pathogenic Leptospira are responsible for leptospirosis, a disease that occurs in many world regions. Leptospirosis is a zoonosis, in other words it affects wild or domestic animals but may be transmitted to humans. A partnership between the Institut Pasteur (Paris) and the INRS Armand-Frappier Santé Biotechnologie Research Center has led to the discovery of a novel mechanism for virulence...
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News | 2023.07.10
Enteric viruses with similar genomes in humans and great apes
A study conducted in Cameroon looked at enteric viruses in humans and some great ape species. These viruses share the same genomes. This "sharing" is thought to be a result of hunting, meat consumption and pillaging by great apes. The findings confirm the scale of pathogen transmission between humans and animals, which can represent a threat to human and animal health.
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Fiche maladie | 2015.10.06
Candidiasis
Fungi (yeast) of the Candida genus can cause superficial infections affecting the mucous membranes or skin, and invasive infections, either localized to one organ or generalized throughout the body. Of the 200 known species of Candida, around twenty are responsible for human infection. Candida yeasts are often responsible for severe, hospital-acquired infections.
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News | 2017.09.15
Lyme disease – chipmunks may affect tick infection but the risk of transmission is more complex
Lyme disease is caused by bacteria transmitted by the bite of an infected tick of the Ixodes genus. Researchers from the Institut Pasteur have investigated tick infection when Siberian chipmunks are present, as these rodents are thought to be a reservoir for the bacteria. This pet, which was popular in the 1970s, was introduced to some forests where it now thrives, like in Sénart Forest, south-...
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News | 2018.01.23
Neurobiologist Jean-Pierre Changeux tells us the story of the nicotinic acetylcholine receptor
As the Institut Pasteur prepares to celebrate its 130th anniversary on November 14, 2018, we talk to Jean-Pierre Changeux about the discovery of this ion channel-linked neuroreceptor that revolutionized neuroscience. On February, the researcher publishes a paper in Trends in Neuroscience providing an account of how this receptor's ion channel was structurally identified.The nicotinic...
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Document de presse | 2022.06.29
Rethinking the rabies vaccine
Rabies virus kills over 50,000 people each year. Although current rabies vaccines are effective, they do not offer lifelong protection and booster doses are required. Institut Pasteur scientists, in collaboration with researchers from La Jolla Institute for Immunology (LJI) in the United States, captured new high-resolution views of rabies virus, revealing potential vaccine targets. These...
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News | 2023.08.17
ECOMORE 2: understanding environmental impact on the emergence of infectious diseases in Southeast Asia.
Due to population growth and economic development, our planet is experiencing significant changes in natural ecosystems that may lead to the re-emergence of infectious diseases. For 5 years, ECOMORE 2 project, coordinated by Institut Pasteur in partnership with the Institut Pasteur du Cambodge, the Institut Pasteur du Laos, the National Health Laboratory (NHL) of Myanmar, the Research Institute...
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Document de presse | 2016.04.11
Malaria: a new route of access to the heart of the parasite
Scientists have just identified an Achilles heel in the parasite that causes malaria, by showing that its optimum development is dependent on its ability to expropriate RNA molecules in infected cells – a host-pathogen interaction that had never previously been observed. Although the precise function of this deviation remains mysterious, these findings open new perspectives for the targeted...