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  1. Article | 2019.06.25

    Infectious diseases emergence and transmission dynamics (23 entities)

    This thematic area explores the process of infectious disease emergence through its biological and epidemiological components, including the crossing of the species barrier, pathogen identification, transmission dynamics, and epidemic surveillance and monitoring.

  2. Article | 2021.08.03

    Neuro-inflammation and Neuro-infection

    Department of Cell Biology & InfectionSandrine Etienne-Manneville - Astrocytic responses to inflammatory situationsAstrocytes form the majority of glial cells of the central nervous system. They play a key role in brain homeostasis, they serve as physical and nutritional support for neurons and directly participate in synaptic transmission. In inflammatory situations, such as those...

  3. Article | 2021.08.03

    Neurodegenerative Diseases​

    Department of Cell Biology & InfectionSandrine Etienne-Manneville - Astrocytic responses to inflammatory situationsAstrocytes form the majority of glial cells of the central nervous system. They play a key role in brain homeostasis, they serve as physical and nutritional support for neurons and they directly participate in synaptic transmission. In inflammatory situations, such as...

  4. Article | 2021.08.03

    Neurodevelopmental and psychiatric diseases

    Department of Cell Biology & InfectionChiara Zurzolo - Mechanisms of intercellular communication in the brain and role in the progression of neurodegenerative diseasesNeurodegenerative diseases (NDs) are protein conformational disorders linked to the propagation of protein misfolding in the brain in a prion-like manner. We discovered that, like prions, misfolded amyloid aggregates of a-...

  5. Article | 2019.06.20

    New diagnostic approaches and innovative therapies

    Developing innovative therapeutic approaches to improve treatment of patients and provide a rapid and permanent cure.

  6. Article | 2019.06.25

    Novel approaches to diagnosis, vaccination and therapy (12 entities)

    This thematic area gathers investigators with a common interest in translational research. It addresses the design, development and evaluation of candidate vaccines, therapeutics, diagnosis tools, and immunotherapies, for conversion of scientific breakthroughs into improved human health.

  7. Article | 2019.06.18

    Parasites

    Teams of the Departments of Parasites and Insect Vectors and of Structural Biology and Chemistry are dedicated to characterize the dissemination and the mechanisms of drug resistance of parasitic infections and to develop alternative strategies to fight them.

  8. Article | 2019.06.25

    Pathogen genomics and microbiota (8 entities)

     Research in this thematic area explores the genomes of infectious agents in relation with their evolution. It also investigates the regulation of the microbiota composition and the mechanisms by which microbiota dysbiosis influences antimicrobial immunity.

  9. Article | 2019.06.25

    Pathogen biology (12 entities)

    In addition to causing many infectious diseases, pathogens provide insightful information on fundamental biological processes. Research in this thematic area investigates the mechanisms underpinning the virulence of pathogens of global public health and/or veterinary concern.

  10. Article | 2021.08.03

    Sensory Disorders

     Department of NeurosciencesAziz El-Amraoui - Progressive sensory disorders, pathophysiology and therapyHearing and vision are essential for every significant activity of daily life, ranging from social interactions and mobility to an appreciation of music, art, and nature. Because of their high prevalence, untreated decline of these sensory deficits has a vast economic & societal...

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