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  1. Article | 2021.08.03

    Neurodevelopmental and psychiatric diseases

    Department of Cell Biology & InfectionChiara Zurzolo - Mechanisms of intercellular communication in the brain and role in the progression of neurodegenerative diseasesNeurodegenerative diseases (NDs) are protein conformational disorders linked to the propagation of protein misfolding in the brain in a prion-like manner. We discovered that, like prions, misfolded amyloid aggregates of a-...

  2. Article | 2019.06.20

    New diagnostic approaches and innovative therapies

    Developing innovative therapeutic approaches to improve treatment of patients and provide a rapid and permanent cure.

  3. Article | 2019.06.25

    Novel approaches to diagnosis, vaccination and therapy (12 entities)

    This thematic area gathers investigators with a common interest in translational research. It addresses the design, development and evaluation of candidate vaccines, therapeutics, diagnosis tools, and immunotherapies, for conversion of scientific breakthroughs into improved human health.

  4. Article | 2019.06.18

    Parasites

    Teams of the Departments of Parasites and Insect Vectors and of Structural Biology and Chemistry are dedicated to characterize the dissemination and the mechanisms of drug resistance of parasitic infections and to develop alternative strategies to fight them.

  5. Article | 2019.06.25

    Pathogen genomics and microbiota (8 entities)

     Research in this thematic area explores the genomes of infectious agents in relation with their evolution. It also investigates the regulation of the microbiota composition and the mechanisms by which microbiota dysbiosis influences antimicrobial immunity.

  6. Article | 2019.06.25

    Pathogen biology (12 entities)

    In addition to causing many infectious diseases, pathogens provide insightful information on fundamental biological processes. Research in this thematic area investigates the mechanisms underpinning the virulence of pathogens of global public health and/or veterinary concern.

  7. Article | 2021.08.03

    Sensory Disorders

     Department of NeurosciencesAziz El-Amraoui - Progressive sensory disorders, pathophysiology and therapyHearing and vision are essential for every significant activity of daily life, ranging from social interactions and mobility to an appreciation of music, art, and nature. Because of their high prevalence, untreated decline of these sensory deficits has a vast economic & societal...

  8. Article | 2019.06.18

    Transversal

    Teams from the Department of Structural Biology and Chemistry and from Computational Biology develop new molecules, technologies and approaches to detect and fight AMR.

  9. Article | 2019.08.06

    Vaccinology and Immunotherapy Initiative: Innovation – Vaccine Candidates

    The Institut Pasteur has a distinguished history of vaccine development as a means to improve global health. A stronghold of the Institut Pasteur in vaccines is the development of novel technologies for vaccine design and delivery with several candidates currently under clinical evaluation, either licensed to development and commercialization partners or under Institut Pasteur sponsorship.

  10. Article | 2019.08.06

    Vaccinology and Immunotherapy Initiative: Clinical Research

    Clinical Research in Vaccinology and Immunotherapy at Institut Pasteur includes clinical studies with the advanced vaccine candidates developed by Institut Pasteur (described as part of the Innovation – Vaccine candidates, immune-monitoring of Institut Pasteur sponsored clinical trials as well as in collaboration with partners, and cohort and surveillance studies to uncover the disease-specific...

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