Article | 2019.06.20
Understanding the main stages in tumor development to identify markers for very early diagnosis and new therapeutic targets.
Article | 2019.06.20
Identifying and combating the risk factors behind tumor development.
Article | 2021.08.03
Department of Cell Biology & InfectionThomas Wollert - Preventing neurodegeneration by cellular recycling The hallmark of many neurodegenerative disorders including Parkinson’s and Alzheimer’s disease is the accumulation of toxic protein aggregates in neurons. We study cellular recycling systems that efficiently degrade such aggregates. Autophagy is one of the most versatile...
Article | 2019.06.18
Christophe D’Enfert-Fungal - Biology and Pathogenicity Unit The Fungal Biology and Pathogenicity Unit explores different aspects of the biology of the fungal pathogens of humans Candida albicans and Aspergillus fumigatus with focuses on the mechanisms governing genome stability, biofilm formation and their tolerance to antifungals, and cell wall biogenesis. See the website...
Article | 2019.06.25
Pathogens have evolved sophisticated strategies to infect, propagate and persist within their hosts. Here, host-pathogen interactions are studied at the molecular, cellular, organ and whole-organism levels. The long-term goal of these studies is to identify novel targets for diagnosis, vaccination and treatment.
Article | 2019.06.25
This thematic area explores the process of infectious disease emergence through its biological and epidemiological components, including the crossing of the species barrier, pathogen identification, transmission dynamics, and epidemic surveillance and monitoring.
Article | 2021.08.03
Department of Cell Biology & InfectionSandrine Etienne-Manneville - Astrocytic responses to inflammatory situationsAstrocytes form the majority of glial cells of the central nervous system. They play a key role in brain homeostasis, they serve as physical and nutritional support for neurons and directly participate in synaptic transmission. In inflammatory situations, such as those...
Article | 2021.08.03
Department of Cell Biology & InfectionSandrine Etienne-Manneville - Astrocytic responses to inflammatory situationsAstrocytes form the majority of glial cells of the central nervous system. They play a key role in brain homeostasis, they serve as physical and nutritional support for neurons and they directly participate in synaptic transmission. In inflammatory situations, such as...
Article | 2021.08.03
Department of Cell Biology & InfectionChiara Zurzolo - Mechanisms of intercellular communication in the brain and role in the progression of neurodegenerative diseasesNeurodegenerative diseases (NDs) are protein conformational disorders linked to the propagation of protein misfolding in the brain in a prion-like manner. We discovered that, like prions, misfolded amyloid aggregates of a-...
Article | 2019.06.20
Developing innovative therapeutic approaches to improve treatment of patients and provide a rapid and permanent cure.