1. Article | 2019.06.18

   Vaccinology and Immunotherapy Initiative

   Vaccines have had a major positive impact on public health world-wide through disease prevention that can be measured in millions of lives saved. Despite the successes, we still face major challenges in vaccine and immunotherapy development for global, neglected, or newly emerging diseases and in our understanding of the determinants of vaccine protection. To address these issues, the Institut...

2. Article | 2019.06.18

   Bacteria

   34 teams from seven departments are addressing the antibiotic resistance challenge with multidisciplinary approaches to characterize and prevent the emergence and the dissemination of antibiotic resistance genes and resistant bacteria and to develop new drugs and alternative strategies to fight bacterial infections.

3. Article | 2019.06.20

   Cancer Biology

   Understanding the main stages in tumor development to identify markers for very early diagnosis and new therapeutic targets.

4. Article | 2019.06.20

   Cancer and microbes

   Identifying and combating the risk factors behind tumor development.

5. Article | 2021.08.03

   Diagnosis and therapy

   Department of Cell Biology & InfectionThomas Wollert - Preventing neurodegeneration by cellular recycling The hallmark of many neurodegenerative disorders including Parkinson’s and Alzheimer’s disease is the accumulation of toxic protein aggregates in neurons. We study cellular recycling systems that efficiently degrade such aggregates. Autophagy is one of the most versatile...

6. Article | 2019.06.18

   Fungi

   Christophe D’Enfert-Fungal - Biology and Pathogenicity Unit  The Fungal Biology and Pathogenicity Unit explores different aspects of the biology of the fungal pathogens of humans Candida albicans and Aspergillus fumigatus with focuses on the mechanisms governing genome stability, biofilm formation and their tolerance to antifungals, and cell wall biogenesis. See the website...

7. Article | 2019.06.25

   Host-pathogen interactions (33 entities)

   Pathogens have evolved sophisticated strategies to infect, propagate and persist within their hosts. Here, host-pathogen interactions are studied at the molecular, cellular, organ and whole-organism levels. The long-term goal of these studies is to identify novel targets for diagnosis, vaccination and treatment. 

8. Article | 2019.06.25

   Infectious diseases emergence and transmission dynamics (23 entities)

   This thematic area explores the process of infectious disease emergence through its biological and epidemiological components, including the crossing of the species barrier, pathogen identification, transmission dynamics, and epidemic surveillance and monitoring.

9. Article | 2021.08.03

   Neuro-inflammation and Neuro-infection

   Department of Cell Biology & InfectionSandrine Etienne-Manneville - Astrocytic responses to inflammatory situationsAstrocytes form the majority of glial cells of the central nervous system. They play a key role in brain homeostasis, they serve as physical and nutritional support for neurons and directly participate in synaptic transmission. In inflammatory situations, such as those...

10. Article | 2021.08.03

    Neurodegenerative Diseases​

    Department of Cell Biology & InfectionSandrine Etienne-Manneville - Astrocytic responses to inflammatory situationsAstrocytes form the majority of glial cells of the central nervous system. They play a key role in brain homeostasis, they serve as physical and nutritional support for neurons and they directly participate in synaptic transmission. In inflammatory situations, such as...

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