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Fiche maladie | 2015.10.06
Chagas disease
Chagas disease is a neglected parasitic infection. It is transmitted by a hematophagous insect and mainly affects the American continent, where over 100 million people are exposed to it. In some cases, the infection takes a chronic form, causing irreversible lesions and death. Every year, Chagas disease claims thousands of lives. Chagas disease is the parasitic disease with the highest socio-...
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News | 2021.01.20
A vaccine candidate based on glycochemistry targets shigellosis: promising Phase 1 results
Diarrheal diseases are the world's second leading cause of death in children aged under 5 years, and of these, bacillary dysentery or shigellosis remains a major public health issue. This disease is most prevalent in African and South-East Asian countries, where it is endemic despite significant improvements in terms of access to drinking water and management of contaminated water. Consequently,...
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News | 2021.01.25
Covid-19: impacts of the pandemic on the human microbiome
The Covid-19 epidemic has had great impact on people’s lives across the world. The disease, physical distancing and lockdown measures have had multiple effects on health. One less-studied effect is the consequence on the microbiome. A group of prominent microbiome researchers in biomedical and social science, coordinated by Brett Finlay (University of British Columbia) and Tamara Giles-Vernick (...
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News | 2021.02.02
Glioblastoma : Tunelling nanotubles could be a new therapeutic target
Cancer is the leading cause of mortality in France. In the last 40 years, survival rates have increased for several types of cancer, such as breast or prostate cancer. However, brain cancer is still an incurable disease, as it usually becomes resistant to therapy and relapses in a relatively short time. The outcome is almost inexorably the patient death. Researchers headed by Chiara Zurzolo at...
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Document de presse | 2021.01.25
COVID-19: progress update on the Institut Pasteur's scientific response and vaccine candidate research programs
Since early 2020, the Institut Pasteur has been engaged in research in several of its areas of scientific expertise, including virology, diagnostics, pathophysiology, epidemiology, modeling, therapeutic research and vaccine research. A number of research programs to find a vaccine for SARS-CoV-2, the virus responsible for the COVID-19 epidemic, are under way. In light of the intermediate results...
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Fiche maladie | 2015.10.06
West Nile
West Nile virus is transmitted to humans by mosquitoes. It causes sudden fever, sometimes associated with neurological complications that can be severe in many animal species. Since it was first identified in East Africa, the virus has been observed on every continent. It is currently endemic in the Mediterranean Basin, Central Europe and North America, where it is responsible for fatal human...
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Fiche maladie | 2015.10.06
Leishmaniasis
Leishmaniasis is a parasitic disease that causes severely debilitating cutaneous or visceral lesions, which can be fatal if left untreated. The plural form "leishmaniases" is sometimes used, as the disease is actually a group of diseases caused by different parasites of the genus Leishmania, transmitted by the bites of sandflies. These parasitic diseases are considered emerging neglected diseases...
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News | 2021.01.26
Candida infections: the role of the Rme1 protein in the formation of chlamydospores
Candida albicans is a yeast that naturally resides in the human intestinal tract, but which can prove to be a formidable pathogen in the event of a drop in the host's immune defences, responsible for superficial or generalised ailments, sometimes fatal. A research group including researchers from the Institut Pasteur has studied the morphological mechanisms facilitating infection by C. albicans....
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News | 2021.02.01
COVID-19: New diagnostic tool for use outside the lab, offering the same efficacy as a PCR test
PCR tests are currently the gold standard for detecting SARS-CoV-2. These tests are reliable, but their complexity makes them difficult to use for point-of-care testing (POCT), in other words testing outside the laboratory. Scientists from the Institut Pasteur and ESPCI Paris-PSL have developed COVIDISC, a new portable device for this purpose. Since 2014, Institut Pasteur scientists have...
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News | 2021.02.05
COVID-19 risk factors surveillance among healthcare workers: a study implemented by MediLabSecure Project
According to the WHO recommendations, a multi-centre surveillance study has been implemented among healthcare workers in five African countries: Burkina Faso, Cameroon, Niger, Central African Republic and Madagascar. Coordinated by Institut Pasteur, this cohort study aims to identify the contamination risk factors and better understand the transmission/spread of the virus. The revue “...
