1. News | 2020.10.21

   Cholera: researchers track the origin of epidemics in Europe since 1970

   Thanks to the collection of cholera vibrio strains from the National Reference Centre for Vibrio and Cholera (hosted by the Enteric Bacterial Pathogens Unit at the Institut Pasteur in Paris) and in collaboration with scientists from the Cantacuzino Institute (Bucharest, Romania) and the Public Health Agency of Canada, a retrospective analysis of the latest cholera epidemics in Europe, related to...

2. News | 2020.10.21

   Cholera: study of the strain responsible for the 2018-2019 epidemic in Zimbabwe

   Between September 2018 and March 2019, a cholera epidemic took place in Zimbabwe, causing 10 000 cases and 69 deaths. The Enteric Bacterial Pathogens Unit at the Institut Pasteur (Paris) took part to the study of a strain of Vibrio cholerae (Vibrio cholerae O1) responsible for this epidemic. This study was made with scientists from the National Institute for Communicable Diseases of South...

3. News | 2020.10.27

   Antibiotic resistance: the Institut Pasteur's microbiological expertise and unique collection of resistant strains contribute to research on group A streptogramins

   The Institut Pasteur's outstanding collection of bacterial strains has played a key role in research at the University of California. The collection was used in a study exploring how the modification of group A streptogramins, a class of antibiotics discovered and isolated in France in the 1960s, can restore their efficacy by enabling them to overcome the resistance mechanisms employed by the...

4. News | 2020.11.02

   New Edition Of The Free On-Line Mooc Tuberculosis

   Tuberculosis (TB) remains one of the ten leading causes of death worldwide and the biggest killer among infectious diseases, surpassing even AIDS and malaria. Although it is hoped that TB can be eliminated within the next couple of decades, the incidence is currently falling by only 1.5% per year. Each year there are about 10 million new cases of TB and a half a million of these are multi-drug...

5. Document de presse | 2020.11.03

   Number of Covid-19 deaths in the under-65s: a more reliable indicator for assessing infection rates in populations

   Simply comparing the total number of deaths across countries may provide a misleading representation of the underlying level of transmission of SARS-CoV-2, the virus that causes COVID-19, because of large differences in reported COVID-19 death rates in elderly populations in different countries.The research conducted by the University of Cambridge, the Institut Pasteur and the CNRS, published...

6. News | 2020.11.04

   COVID-19: Senlis Criminal Court convicts the author of a fake news video for defamation

   On November 2, 2020, Senlis Criminal Court convicted the author of a misleading video claiming that the Institut Pasteur invented COVID-19, posted online on March 17, 2020, of public defamation towards the Institut Pasteur. The author's words, which were untrue and unfounded and were based on a misinterpretation of a patent submitted in 2004, led to a wave of strong reactions against the Institut...

7. News | 2020.11.09

   Leptospirosis: elucidation of a new gene regulation mechanism based on DNA modification

   Pathogenic Leptospira are responsible for leptospirosis, a disease that occurs in many world regions. Leptospirosis is a zoonosis, in other words it affects wild or domestic animals but may be transmitted to humans. A partnership between the Institut Pasteur (Paris) and the INRS Armand-Frappier Santé Biotechnologie Research Center has led to the discovery of a novel mechanism for virulence...

8. News | 2020.12.03

   HIV: one stage in replication may occur in macrophage nuclei

   Understanding the replication mechanisms of HIV in the body is vital for the development of more targeted treatments. Research into macrophages is particularly crucial, since these immune cells are the first line of cellular defense against infectious agents, and HIV accumulates silently in them, making them a reservoir for the virus – even in people receiving treatment. Scientists from the...

9. News | 2020.11.12

   Alzheimer: how endogenously formed Tau aggregates fail to be degraded

   Alzheimer's disease is a progressive neurodegenerative disorder that mainly affects memory, but also other cognitive functions linked to knowledge and involving language, logical thought and learning capacity. This disease generally leads to loss of independence for sufferers. It is one of the leading causes of disability and dependency in elderly people. There is currently no cure for the...

10. News | 2020.11.26

    Urinary tract infections: the mechanisms behind the lack of immune memory in many patients

    Urinary tract infections (UTI) are a group of infectious diseases that predominantly impact healthy adult women, although they can also cause serious disease in men. They are the second most prevalent infection after respiratory infections*. The immune response to UTI is still not well-understood, and a better understanding could help lessen the use of antibiotics for this common infection....

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