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News | 2020.11.04
COVID-19: Senlis Criminal Court convicts the author of a fake news video for defamation
On November 2, 2020, Senlis Criminal Court convicted the author of a misleading video claiming that the Institut Pasteur invented COVID-19, posted online on March 17, 2020, of public defamation towards the Institut Pasteur. The author's words, which were untrue and unfounded and were based on a misinterpretation of a patent submitted in 2004, led to a wave of strong reactions against the Institut...
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News | 2020.11.09
Leptospirosis: elucidation of a new gene regulation mechanism based on DNA modification
Pathogenic Leptospira are responsible for leptospirosis, a disease that occurs in many world regions. Leptospirosis is a zoonosis, in other words it affects wild or domestic animals but may be transmitted to humans. A partnership between the Institut Pasteur (Paris) and the INRS Armand-Frappier Santé Biotechnologie Research Center has led to the discovery of a novel mechanism for virulence...
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News | 2020.12.03
HIV: one stage in replication may occur in macrophage nuclei
Understanding the replication mechanisms of HIV in the body is vital for the development of more targeted treatments. Research into macrophages is particularly crucial, since these immune cells are the first line of cellular defense against infectious agents, and HIV accumulates silently in them, making them a reservoir for the virus – even in people receiving treatment. Scientists from the...
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News | 2020.11.12
Alzheimer: how endogenously formed Tau aggregates fail to be degraded
Alzheimer's disease is a progressive neurodegenerative disorder that mainly affects memory, but also other cognitive functions linked to knowledge and involving language, logical thought and learning capacity. This disease generally leads to loss of independence for sufferers. It is one of the leading causes of disability and dependency in elderly people. There is currently no cure for the...
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News | 2020.11.26
Urinary tract infections: the mechanisms behind the lack of immune memory in many patients
Urinary tract infections (UTI) are a group of infectious diseases that predominantly impact healthy adult women, although they can also cause serious disease in men. They are the second most prevalent infection after respiratory infections*. The immune response to UTI is still not well-understood, and a better understanding could help lessen the use of antibiotics for this common infection....
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Article | 2020.11.12
Ullmann Class (2020-2023)
Promotion PPU 2020-2023Ph.D. StudentUndergraduate StudiesLaboratoryPhd DirectorLab headPhd ProjectDoctoral schoolPPU studentsAguirre Botero Manuela CamilleUniversity of Heidelberg, Heidelberg, GermanyMalaria Infection & ImmunityRogerio AminoRogerio AminoProtection mechanisms of antibodies targeting malaria sporozoitesBioSPC ED 562 Bio Sorbonne Paris CitéBoyko AlexandraFaculty of...
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Document de presse | 2020.11.16
Operation and reliability of RT-PCR tests in the detection of SARS-CoV-2
The National Reference Center (CNR) for Respiratory Viruses at the Institut Pasteur specializes in viruses such as influenza and bronchiolitis in infants. As an expert center in France, the CNR is responsible for monitoring cases of respiratory infections and for epidemic surveillance. When a new virus emerges, like the novel coronavirus in China, the CNR's task is to do everything it can to...
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News | 2020.11.18
Pneumococcal infections: KDM6B, a key epigenetic regulator in the cellular response
Scientists from the Institut Pasteur have contributed to the discovery of a mechanism that regulates the response to pneumococcal infections between asymptomatic and severe forms. Pneumococci are bacteria that are naturally present in the human respiratory tract, but they are also one of the main causes of meningitis, pneumonia and acute otitis media. According to Santé publique France,1 the...
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News | 2020.11.20
Zika outbreaks fostered by virus-permissive mosquitoes
What factors facilitate the emergence of a previously unknown virus in the human population? Scientists from the CNRS, the Institut Pasteur and the IRD, in collaboration with the Institut Pasteur International Network and with several other institutions worldwide, have helped answer that question for the Zika virus. Their study sheds light on regional and continental disparities in Zika...
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Document de presse | 2021.03.07
COVID-19: neutralizing immune response lasts longer in women than in men
As part of the SEROCoV-HUS study, teams from Strasbourg University Hospital and the Institut Pasteur monitored 308 hospital staff who had previously contracted a mild form of SARS-CoV-2. The scientists demonstrated that neutralizing antibodies could be detected in 84% of them up to 6 months after infection, but that the level fell more quickly in men than in women. These results seem to suggest...
