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News | 2020.10.27
Antibiotic resistance: the Institut Pasteur's microbiological expertise and unique collection of resistant strains contribute to research on group A streptogramins
The Institut Pasteur's outstanding collection of bacterial strains has played a key role in research at the University of California. The collection was used in a study exploring how the modification of group A streptogramins, a class of antibiotics discovered and isolated in France in the 1960s, can restore their efficacy by enabling them to overcome the resistance mechanisms employed by the...
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News | 2020.11.02
New Edition Of The Free On-Line Mooc Tuberculosis
Tuberculosis (TB) remains one of the ten leading causes of death worldwide and the biggest killer among infectious diseases, surpassing even AIDS and malaria. Although it is hoped that TB can be eliminated within the next couple of decades, the incidence is currently falling by only 1.5% per year. Each year there are about 10 million new cases of TB and a half a million of these are multi-drug...
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Document de presse | 2020.11.03
Number of Covid-19 deaths in the under-65s: a more reliable indicator for assessing infection rates in populations
Simply comparing the total number of deaths across countries may provide a misleading representation of the underlying level of transmission of SARS-CoV-2, the virus that causes COVID-19, because of large differences in reported COVID-19 death rates in elderly populations in different countries.The research conducted by the University of Cambridge, the Institut Pasteur and the CNRS, published...
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News | 2020.11.04
COVID-19: Senlis Criminal Court convicts the author of a fake news video for defamation
On November 2, 2020, Senlis Criminal Court convicted the author of a misleading video claiming that the Institut Pasteur invented COVID-19, posted online on March 17, 2020, of public defamation towards the Institut Pasteur. The author's words, which were untrue and unfounded and were based on a misinterpretation of a patent submitted in 2004, led to a wave of strong reactions against the Institut...
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News | 2020.11.09
Leptospirosis: elucidation of a new gene regulation mechanism based on DNA modification
Pathogenic Leptospira are responsible for leptospirosis, a disease that occurs in many world regions. Leptospirosis is a zoonosis, in other words it affects wild or domestic animals but may be transmitted to humans. A partnership between the Institut Pasteur (Paris) and the INRS Armand-Frappier Santé Biotechnologie Research Center has led to the discovery of a novel mechanism for virulence...
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News | 2020.12.03
HIV: one stage in replication may occur in macrophage nuclei
Understanding the replication mechanisms of HIV in the body is vital for the development of more targeted treatments. Research into macrophages is particularly crucial, since these immune cells are the first line of cellular defense against infectious agents, and HIV accumulates silently in them, making them a reservoir for the virus – even in people receiving treatment. Scientists from the...
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News | 2020.11.12
Alzheimer: how endogenously formed Tau aggregates fail to be degraded
Alzheimer's disease is a progressive neurodegenerative disorder that mainly affects memory, but also other cognitive functions linked to knowledge and involving language, logical thought and learning capacity. This disease generally leads to loss of independence for sufferers. It is one of the leading causes of disability and dependency in elderly people. There is currently no cure for the...
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News | 2020.11.26
Urinary tract infections: the mechanisms behind the lack of immune memory in many patients
Urinary tract infections (UTI) are a group of infectious diseases that predominantly impact healthy adult women, although they can also cause serious disease in men. They are the second most prevalent infection after respiratory infections*. The immune response to UTI is still not well-understood, and a better understanding could help lessen the use of antibiotics for this common infection....
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Article | 2020.11.12
Ullmann Class (2020-2023)
Promotion PPU 2020-2023Ph.D. StudentUndergraduate StudiesLaboratoryPhd DirectorLab headPhd ProjectDoctoral schoolPPU studentsAguirre Botero Manuela CamilleUniversity of Heidelberg, Heidelberg, GermanyMalaria Infection & ImmunityRogerio AminoRogerio AminoProtection mechanisms of antibodies targeting malaria sporozoitesBioSPC ED 562 Bio Sorbonne Paris CitéBoyko AlexandraFaculty of...
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Document de presse | 2020.11.16
Operation and reliability of RT-PCR tests in the detection of SARS-CoV-2
The National Reference Center (CNR) for Respiratory Viruses at the Institut Pasteur specializes in viruses such as influenza and bronchiolitis in infants. As an expert center in France, the CNR is responsible for monitoring cases of respiratory infections and for epidemic surveillance. When a new virus emerges, like the novel coronavirus in China, the CNR's task is to do everything it can to...
