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Article | 2020.03.16
Coronavirus: all COVID-19 news from the Institut Pasteur
On January 9, 2020, Chinese health authorities and the World Health Organization (WHO) officially announced the discovery of a novel coronavirus (first named 2019-nCoV, then officially SARS-CoV-2). This new virus is the pathogen responsible for the infectious respiratory disease called COVID-19 (CoronaVIrus Disease). Following the announcement of the first cases and the declaration of...
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News | 2020.11.12
Alzheimer: how endogenously formed Tau aggregates fail to be degraded
Alzheimer's disease is a progressive neurodegenerative disorder that mainly affects memory, but also other cognitive functions linked to knowledge and involving language, logical thought and learning capacity. This disease generally leads to loss of independence for sufferers. It is one of the leading causes of disability and dependency in elderly people. There is currently no cure for the...
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News | 2020.11.30
Autoinflammatory diseases: a yeast sugar as a potential treatment
Autoinflammatory diseases, like autoimmune diseases, are disorders caused by immune system dysfunction. They develop into chronic inflammatory diseases. Institut Pasteur scientists have observed that a natural sugar in the yeast cell wall may reduce excessive inflammation in some of these conditions, and could therefore be used as a treatment.Antibodies that attack the normal constituents of the...
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News | 2021.02.05
COVID-19 risk factors surveillance among healthcare workers: a study implemented by MediLabSecure Project
According to the WHO recommendations, a multi-centre surveillance study has been implemented among healthcare workers in five African countries: Burkina Faso, Cameroon, Niger, Central African Republic and Madagascar. Coordinated by Institut Pasteur, this cohort study aims to identify the contamination risk factors and better understand the transmission/spread of the virus. The revue “...
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News | 2021.03.08
Piecing together past epidemics by studying the human genome
Tuberculosis is one of the most deadly infectious diseases in the world, and it is the most deadly disease in Europe's history. It is generally caused by the Mycobacterium tuberculosis bacterium. Scientists have studied the impact of tuberculosis outbreaks on the human genome over the past 10,000 years.Our genome is partly shaped by natural selection. Genes that increase our chances of survival...
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News | 2021.06.01
An imaging and modeling approach to characterize the structure of DNA in human cells
The structure of DNA and chromosomes is a major focus of research, but still holds a number of mysteries. Scientists from the Institut Pasteur and the CNRS have developed a new method for quantifying chromatin loops and observing chromosomes at high resolution.In our cells, DNA is coiled up many times, enabling it to fit into the cell nucleus, which is approximately 200,000 times smaller than the...
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News | 2021.08.13
Low number of COVID-19 cases in Lao PTR: a seroprevalence study to confirm this figure
In 2020 when many countries around the world struggled with a large burden of COVID-19 cases, the Lao PDR stood out as a country with low reported numbers of SARS-CoV-2 infections. Was it due to a low circulation of the virus or to an inadequate surveillance system? To answer this question, a seroprevalence study has been conducted by Institut Pasteur du Laos, in collaboration with Institut...
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News | 2023.01.09
Bacterial pathogenicity: improving understanding of an essential process – molecule secretion
Bacteria are not just passive; they are capable of interacting with their close environment. How? One way is by secreting molecules outside their envelope using complex protein machinery. Scientists have recently elucidated the formation mechanisms underpinning one of these secretion systems, thereby paving the way for potential therapeutic applications.
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Document de presse | 2023.06.12
How the brain detects and regulates inflammation
How does the brain adapt our behavior in response to an infection or injury? A multidisciplinary team of scientists from the Institut Pasteur, CNRS and Inserm have revealed the existence of a circuit involved in sensing and also in the regulation of the anti-inflammatory response orchestrated by different brain regions. This circuit detects inflammation in the blood and organizes and regulates...
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Article | 2024.02.01
International programs
To meet current global health challenges, the Institut Pasteur is developing and coordinating major international projects, run mainly in conjunction with members of the Institut Pasteur International Network. As well as furthering knowledge, these programs help to increase local skills, build up equipment, and assist health authorities in drawing up recommendations to improve the care of...