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Document de presse | 2004.01.19
A major advance in combatting Buruli ulcer
An international group of scientists coordinated by Stewart Cole of the Institut Pasteur has just discovered the genetic basis for the synthesis of the Mycobacterium ulcerans toxin, responsible for Buruli ulcer. Press release Paris, january 20, 2004 A rapidly-expanding emerging disease, Buruli ulcer is the one of the most common mycobacterial infections after...
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Document de presse | 2013.07.04
Transmissibility of new coronavirus too low to trigger global epidemic at this stage
In a study published online on July 5, 2013 for the medical journal The Lancet, a team from the Institut Pasteur suggests that the coronavirus MERS-CoV, in its current form, is not capable of triggering a global epidemic. However, it should not be assumed that the virus’ transmissibility will not increase if the virus mutates or if transmission occurs at a one-off event where large numbers...
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Document de presse | 2013.08.01
Dengue: identifying mosquito genetic factors that control virus transmission
Dengue is currently the most common insect-borne viral disease of humans worldwide. Scientists from the Institut Pasteur, the French National Center for Scientific Research (CNRS), and the Armed Forces Research Institute of Medical Sciences (AFRIMS) have discovered several genetic factors controlling the transmission of various dengue virus strains in a natural population of mosquitoes in...
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Document de presse | 2013.09.30
Potential therapeutic targets for blocking AIDS virus replication
Scientists from the Institut Pasteur and Inserm have identified several proteins in humans as potential new therapeutic targets for treating the AIDS virus. These proteins are part of a complex cellular mechanism that blocks the virus replication in cells called macrophages. The discovery of this mechanism and the proteins involved gives scientists a solid theoretical basis for developing new...
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Document de presse | 2013.10.09
Fine-tuning the approach to malaria and toxoplasmosis research
A study carried out by teams from the Institut Pasteur, the Institut Cochin (Inserm, CNRS, Paris Descartes University), and the Wellcome Trust Centre for Molecular Parasitology at the University of Glasgow, may very well redefine current approaches to malaria and toxoplasmosis research in terms of treatment development. Their research which focuses on the role played by the protein AMA1 (present...
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Document de presse | 2013.11.03
Identification of a new mechanism in immunotherapy for lymphoma
Using innovative dynamic imaging technique, scientists at the Institut Pasteur, Inserm and the VU Medical Center in Amsterdam have uncovered the mode of action of anti-CD20, an antibody therapy frequently used in the treatment of lymphomas (cancers of the immune system) as well as some auto-immune diseases. In a lymphoma model, the scientists have been able to carry out real time in vivo imaging...
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Document de presse | 2013.12.11
Carriers of a genetic mutation show increased dependence on tobacco
Scientists at the Institut Pasteur, the French National Center for Scientific Research (CNRS) and Pierre and Marie Curie University (UPMC) have recently proven that, in mice, nicotine intake – nicotine is the main addictive substance in tobacco – is heavily regulated by a genetic mutation that is very common in humans. This mutation affects the neuronal nicotinic receptor, disrupting...
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Document de presse | 2013.12.12
A prime target for the development of anti-inflammatories
For the first time, scientists from the Institut Pasteur and Inserm have demonstrated the key role played by a particular molecule in intestinal infection. The study was published online in Immunity on December 12, 2013. The molecule, known as ATP, serves as a trigger signal for the inflammatory response targeting pathogenic agents. Using the Shigella flexneri model, the scientists have also...
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Article | 2016.12.02
Health
The Institut Pasteur is putting its scientific expertise to work for the health of populations and individuals. The Institut Pasteur in Paris is home to several national and international centers of expertise that monitor infectious diseases. And the Institut Pasteur Medical Center — which vaccinates thousands of people every year — specializes in infectious and tropical diseases, travel medicine...
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Document de presse | 2016.12.22
Regenerative medicine: senescent cells boost cell reprogramming
The major challenge currently faced in the field of regenerative medicine is how to reprogram differentiated adult cells into other cell types for tissue repair. Scientists from the Institut Pasteur and the CNRS have made a surprising discovery that cellular senescence, usually associated with aging, cancer and inflammation, promotes reprogramming, where cells revert back to a more embryonic-like...