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Document de presse | 2013.09.30
Potential therapeutic targets for blocking AIDS virus replication
Scientists from the Institut Pasteur and Inserm have identified several proteins in humans as potential new therapeutic targets for treating the AIDS virus. These proteins are part of a complex cellular mechanism that blocks the virus replication in cells called macrophages. The discovery of this mechanism and the proteins involved gives scientists a solid theoretical basis for developing new...
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Document de presse | 2013.10.09
Fine-tuning the approach to malaria and toxoplasmosis research
A study carried out by teams from the Institut Pasteur, the Institut Cochin (Inserm, CNRS, Paris Descartes University), and the Wellcome Trust Centre for Molecular Parasitology at the University of Glasgow, may very well redefine current approaches to malaria and toxoplasmosis research in terms of treatment development. Their research which focuses on the role played by the protein AMA1 (present...
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Document de presse | 2013.11.03
Identification of a new mechanism in immunotherapy for lymphoma
Using innovative dynamic imaging technique, scientists at the Institut Pasteur, Inserm and the VU Medical Center in Amsterdam have uncovered the mode of action of anti-CD20, an antibody therapy frequently used in the treatment of lymphomas (cancers of the immune system) as well as some auto-immune diseases. In a lymphoma model, the scientists have been able to carry out real time in vivo imaging...
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Document de presse | 2013.12.11
Carriers of a genetic mutation show increased dependence on tobacco
Scientists at the Institut Pasteur, the French National Center for Scientific Research (CNRS) and Pierre and Marie Curie University (UPMC) have recently proven that, in mice, nicotine intake – nicotine is the main addictive substance in tobacco – is heavily regulated by a genetic mutation that is very common in humans. This mutation affects the neuronal nicotinic receptor, disrupting...
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Document de presse | 2013.12.12
A prime target for the development of anti-inflammatories
For the first time, scientists from the Institut Pasteur and Inserm have demonstrated the key role played by a particular molecule in intestinal infection. The study was published online in Immunity on December 12, 2013. The molecule, known as ATP, serves as a trigger signal for the inflammatory response targeting pathogenic agents. Using the Shigella flexneri model, the scientists have also...
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Article | 2016.12.02
Health
The Institut Pasteur is putting its scientific expertise to work for the health of populations and individuals. The Institut Pasteur in Paris is home to several national and international centers of expertise that monitor infectious diseases. And the Institut Pasteur Medical Center — which vaccinates thousands of people every year — specializes in infectious and tropical diseases, travel medicine...
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Document de presse | 2016.12.22
Regenerative medicine: senescent cells boost cell reprogramming
The major challenge currently faced in the field of regenerative medicine is how to reprogram differentiated adult cells into other cell types for tissue repair. Scientists from the Institut Pasteur and the CNRS have made a surprising discovery that cellular senescence, usually associated with aging, cancer and inflammation, promotes reprogramming, where cells revert back to a more embryonic-like...
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News | 2016.08.25
A new approach for deciphering complex immune responses
The response to infection is highly variable from one individual to another. The Milieu Intérieur consortium, coordinated by Prof. Matthew Albert (Immunobiology of dendritic cells Unit, Institut Pasteur / Inserm) and Dr Lluis Quintana-Murci (Human Evolutionary Genetics Unit, Institut Pasteur / CNRS) seeks to establish the parameters that characterize the immune system of healthy individuals and...
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News | 2017.02.01
Sign up for the upcoming Institut Pasteur MOOCs
As a leading biomedical research center in many fields of health, the Institut Pasteur also has an education center which contributes to the dissemination of scientific and medical knowledge. Some of the Education Center's course offerings are digital, including three MOOCs whose registration period is currently underway, on the topics of medical entomology, epidemiology and...
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Article | 2017.02.27
Infectious diseases pathogenesis in Asia/Pacific
Institut Pasteur International Network Course 2017 -« Infectious diseases pathogenesis in Asia/Pacific »SummaryThe IPIN 2017 course will focus on infectious diseases caused by major pathogens including viruses, bacteria, parasites and fungi, relevant to the East Asia and Southeast Asia regions. The teaching will cover essential molecular mechanisms of pathogen life cycle and host...