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Document de presse | 2013.01.06
Retracing the evolutionary history and emergence of tuberculosis
In association with CEA-Genoscope and the Sanger Institute, scientists at the Institut Pasteur in Paris, the CNRS, INSERM, the Institut Pasteur of Lille, and Université Lille 2 have recently determined the origin of the emergence of the Mycobacterium tuberculosis bacterium, the main causative agent of tuberculosis. Researchers have also provided insights into its evolutionary success. They have...
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Document de presse | 2012.10.08
Rooting out the Cause of Blindness in Type 1 Usher Syndrome
Researchers from the Institut Pasteur, the Institut de la Vision, Inserm, and the Pierre and Marie Curie University have determined the cause of blindness associated with type 1 Usher syndrome (the most common genetic cause of deafness and blindness in humans). They have also shown why rodents, the only animal model currently available for research on this disease, are invulnerable to the vision...
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Document de presse | 2012.06.11
Dormancy of stem cells enables them to remain viable…many days post mortem
Under the direction of Fabrice Chrétien*, in collaboration with Shahragim Tajbakhsh**, researchers from the Institut Pasteur, the Université de Versailles Saint-Quentin-en-Yvelines, the Paris Public Hospital Network (AP-HP), and the CNRS have shown for the first time in humans and mice, the capacity of stem cells to adopt a dormant state when their environment becomes hostile, including several...
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Document de presse | 2012.05.15
A new optical microscopy approach opens the door to better observations in molecular biology
Researchers from the Institut Pasteur and CNRS have set up a new optical microscopy approach that combines two recent imaging techniques in order to visualize molecular assemblies without affecting their biological functions, at a resolution 10 times better than that of traditional microscopes. Using this approach, they were able to observe the AIDS virus and its capsids (containing the HIV...
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Document de presse | 2012.04.18
A new hope in the fight against tuberculosis
Researchers from the Institut Pasteur and Inserm, in collaboration with researchers from the University of Pisa, have uncovered the key role played by specific proteins in the virulence of the mycobacterium responsible for tuberculosis, Mycobacterium tuberculosis. They were able to create an attenuated strain of the mycobacterium, which confers a better protection against tuberculosis than the...
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Document de presse | 2012.03.11
DENFREE: flying towards the efficient control of dengue
Comfortably nested in the salivary glands of mosquitoes, the dengue virus moves around and infects everybody unlucky enough to be bitten. But on the wings of mosquitoes, it can’t possibly go very far and usually stays within a restricted community… unless it “changes vehicle” and travels further away thanks to the infected humans. Starting in January 2012, the Institut...
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Document de presse | 2012.02.13
Europe’s united front against emerging viruses
The new PREDEMICS* project strives to improve current knowledge on certain emerging infectious diseases and develop effective treatment and prevention resources. The European Union will be financing this project to the tune of €11.7 million over a five year period. Coordinated by the Institut Pasteur, this collaborative program unites 17 European research and public health institutions. The...
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Document de presse | 2012.01.22
Launching of the Institut Pasteur in Laos
Today, Monday January 23, 2012, in Vientiane the launch of the Institut Pasteur in Laos was officiated by the Lao Minister of Public Health, professor Som Ock Kingsadat and the President of the Institut Pasteur in Paris, professor Alice Dautry. This is the Institut Pasteur International Network’s 32nd institute. The new research center for infectious and parasitic diseases aims to reduce...
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Document de presse | 2011.02.03
Discovery of a new group of highly susceptible malaria mosquitoes in Africa
In the course of a large genetic study of malaria vector mosquitoes in Burkina Faso, West Africa, researchers at the Institut Pasteur, the French National Center for Scientific Research (CNRS) and their collaborators have discovered a new subspecies of the mosquito Anopheles gambiae, the world’s most important malaria vector. This new mosquito group, which may be an especially...
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Document de presse | 2010.12.01
Identification of the 3D structure of chikungunya virus surface proteins
Researchers at the Institut Pasteur and CNRS, in collaboration with the Synchrotron SOLEIL, have solved the three-dimensional atomic structure of the glycoproteins that envelop the chikungunya virus. This discovery helps to understand how this protein complex is activated in order for the virus to invade target cells. Activation is a key stage in the viral life cycle and understanding its...