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Document de presse | 2005.09.01
Isolation of adult muscle stem cells for skeletal muscle repair
Researchers from the Institut Pasteur and the CNRS have succeeded in isolating muscle stem cells displaying a high potential for muscle repair. These cells, which correspond to satellite cells, were, until now, inaccessible in their native state. Twenty thousand muscle stem/satellite cells were sufficient to promote significant muscle repair in mice, whereas one million cultured muscle precursor...
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Document de presse | 2005.06.14
From stem cells to skeletal muscle : the vital stages deciphered
A laboratory from the Institut Pasteur, associated with the CNRS has taken a determining step towards the understanding of the evolution of skeletal muscle stem cells. Using specific genetic markers, researchers have shown four characteristic stages that mark out the development of the muscle cells from a population of stem cells, which they have identified. This discovery has very important...
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Document de presse | 2005.06.12
A new step towards using stem cells to treat Parkinson's disease
Research by a team at the Institut Pasteur associated with the CNRS published today in Nature Neuroscience is uncoveringsignificant prospects for developing cell therapies to repair the brain. These researchers have succeeded in triggering the transformation of neuronal stem cells from the adult brains of mice into neurons capable of secreting dopamine, a molecule lacking in Parkinson's...
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Document de presse | 2005.05.11
Fifth Human Retrovirus Discovered at Institut Pasteur
After HTLV-1, the first human retrovirus isolated in 1980 in the United States, then HTLV-2, discovered in 1982, and finally HIV-1 and HIV-2, which cause AIDS, isolated at Institut Pasteur in 1983 and 1985, a fifth human retrovirus, HTLV-3, has just been discovered by researchers at Institut Pasteur. Its simian equivalent had been known for about ten years, and researchers were looking for this...
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Document de presse | 2005.02.24
"The Sword and the Shield" - How bacteria develop their virulence by creating multiple variants
Researchers at Institut Pasteur and the French National Institute of Health and Medical Research (Inserm), in association with the Imperial College of London, recently explained why Shigella flexneri bacteria, which cause fatal dysenteries, have several variants (serotypes), thus optimizing their virulence. This discovery, published in Science, is essential to vaccine research as, in order to be...
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Document de presse | 2005.01.05
A candidate Vaccine for West Nile Virus
Researchers at Institut Pasteur recently proved the efficacy of a candidate vaccine against West Nile virus infection in animal model. Their results are published in the Journal of Infectious Diseases. Mosquito-borne West Nile virus is an emerging neurotropic pathogen which is particularly disquieting due to its recent emergence in North America : since 2002, more than 13,000 cases, including 500...
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Document de presse | 2004.09.19
New possibilities for fighting the plague
The plague, one of the most dangerous bacterial diseases for man, is currently reemerging in the world. Comparative genome work coordinated by researchers at Institut Pasteur and at Lawrence Livermore National Laboratory in the US, has shed light on the genetic bases that accompanied the emergence of the extremely virulent plague bacillus from a much less pathogenic ancestor, less than 20,000...
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Document de presse | 2004.05.24
Stem Cells to Repair the Liver: Progress with animal models
Hepatic insufficiency, cirrhosis, liver cancer, etc.: damage to the liver is varied and in serious cases the only alternative is to transplant a healthy organ. However, the lack of available organs limits this practice: in France in 2002, 882 liver transplants were carried out for 1,509 transplant candidates.* Hope for the future is directed towards being able to transplant stem cells capable of...
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Document de presse | 2004.03.14
A new step towards using neural stem celles to repair the brain
A team from the Institut Pasteur associated with the CNRS has just identified a key molecule in the brain capable of attracting new neurons and guiding them towards areas that they could repair. This discovery, previewed on the site Nature Neuroscience (http://www.nature.com/neuro/), brings to the fore a molecule essential for the organization of neuronal circuits in adults. This introduces...
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Document de presse | 2004.02.19
Institut Pasteur/ Inserm : Joint research on the Nipah virus
Two teams from the Institut Pasteur and Inserm, in co-operation with Malaysian researchers, have recently successfully tested a candidate vaccine against the Nipah Virus. This virus, still undiscovered in 1998, was responsible for the deaths of 105 people in Malaysia in 1999. It is expanding at an alarming speed in South-East Asia. Currently there is no treatment in the fight against this...