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Document de presse | 2006.08.31
Malaria Parasite: The Trojan Horse strategy revealed
A team from the Pasteur Institute has just uncovered a subtle mechanism used by the parasite that is responsible for malaria to escape from the immune system during a crucial stage of its cycle inside its mammalian host. This has been made possible thanks to in vivo imaging techniques that make it possible to follow the parasite in real time inside the host organism. This discovery - published in...
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Document de presse | 2006.06.24
Immortal DNA in skeletal muscle stem cells
Researchers at the Pasteur Institute show for the first time the mechanism which adult skeletal muscle stem cells can use to protect their genome from mutations. Before cell division, DNA is duplicated, and each daughter cell inherits one copy. During DNA synthesis, however, errors can arise from this imperfect process. Over time, repeated rounds of cell divisions result in the accumulation of...
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Document de presse | 2006.06.14
Brain research: how is our reward system activated?
Researchers at the Pasteur Institute and the CNRS (French National Centre for Scientific Research), in collaboration with the Karolinska Institute (Stockholm), have recently decoded the molecular bases of our reward system activation, a system which plays a central role in drug dependence. Their work was published in Neuron on 15 June 2006. Press release Paris, june 15, 2006...
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Document de presse | 2006.06.07
Gene expression is governed by spatial organization in the nucleus
Teams at the Institut Pasteur, in collaboration with the CNRS *, have recently discovered an fundamental aspect of cell biology and gene regulation. The results of this work, published in Nature, were obtained by means of the most up-to-date microscopy and image analysis technologies. The researchers were able to observe the position of a gene in real time during its activation and to found that...
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Document de presse | 2006.04.26
A breakthrough in the fight against multiresistance to antibiotics
Multiresistance to antibiotics is a major public health problem. In hospitals, multiresistant pathogens are the main obstacle hindering the control of nosocomial infections. One of the main ways of spreading such resistance is the transfer between bacteria of a class of particularly mobile elements, called integrons, which are carriers of these resistance factors. In a study published today ? in...
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Document de presse | 2006.03.22
Advances in research into a new tuberculosis vaccine
Researchers at the Pasteur Institute and the University of Zaragoza have developed a novel strategy to produce a new tuberculosis vaccine candidate. In an article published in Vaccine, they demonstrate that inactivation of a single gene in the tuberculosis bacillus gives rise to a strain that is more attenuated than BCG and which provides better protection against the disease. This work paves the...
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Document de presse | 2005.12.10
The mechanisms that trigger a debilitating genetic disease have been unveiled
Researchers from the Institut Pasteur and the CNRS have unravelled the cellular mechanisms that are deregulated in polycystic kidney disease (PKD), a life threatening genetic disease that damages kidney function. The authors showed that the dilation of renal tubules leading to cyst formation is linked to a disorganised growth of tubular cells. This research, published in “Nature Genetics...
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Document de presse | 2005.09.28
The keys to life in the extreme cold
A team from the Institut Pasteur and the CNRS, in collaboration with the Genoscope, has deciphered the clever mechanisms developed by a bacterium allowing it to flourish in the heart of Antarctica. In scrutinizing its genome, the researchers revealed several developments in this bacterium's metabolism that allow it both to resist very low temperatures and to flourish there quite effectively....
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Document de presse | 2005.09.05
Cholera: How Parasites Make Bacteria Pathogenic
Vibrio cholerae, the bacteria that causes cholera, is made pathogenic by one of its parasites, the CTX virus. This virus enables the vibrio to produce a toxin that causes the lethal diarrhea of cholera. Researchers at the CNRS and Institut Pasteur have recently proven, in a work published in Molecular Cell, which adaptive method the CTX bacteriophage uses to propagate itself so effectively in the...
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Document de presse | 2005.09.01
Mrs Alice Dautry appointed Managing Director of Institut Pasteur
The Board of Directors of the Institut Pasteur met on 2 September 2005 with a view to appointing the new Managing Director. Press releaseParis, september 2, 2005 During its previous meetings the Board of Directors :- had decided to create a Search Committee in order to receive, attract and then scientifically analyse applications, before drawing up a shortlist of applicants...