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2020.10.24
α1β2γ2 GABAA receptors mediate most inhibitory synaptic transmission in the brain, and are the target of widely used therapeutic drugs such as benzodiazepines...
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2020.03.19
Gene structure, including the transcript leader, is very diverse in fungi. New sequencing data analysis from the RNA Biology of Fungal Pathogens unit revealed...
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2021.02.22
The Lymphopoiesis Unit identified within the first cells that seed the thymus a unique population of lymphoid progenitors. These cells can generate lymphoid...
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2020.10.17
Ludovic Deriano’s Unit studied cells mutated for NHEJ, the canonical repair pathway for DNA double-strand break. The researchers showed that those transformed...
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2021.05.03
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Emerging and re-emerging viruses are key players among the different pathogens that have caused recent epidemics, as attested by several...
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2020.03.05
Cells in vivo organize into 3D structures that underlie the shape and mechanics of tissues, as well as their biological function. Researchers mapped how...
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2020.07.16
Triplet repeat expansions are responsible for more than two dozen neurological and developmental disorders. Shortening these repeats with endonucleases could...
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2020.03.27
Replicative DNA polymerases have evolved the ability to copy the genome with high processivity and fidelity. In Eukarya and Archaea, their processivity is...
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2020.07.22
Aptamers can be thought of as analogs of antibodies entirely composed of nucleic acids (DNA or RNA). They can be used in a wide range of applications but they...
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2020.07.03
The ARIA software suite developed at Institut Pasteur automates the analysis of NMR data to calculate three-dimensional structures of macromolecules. To...