1. News | 2014.10.06

   Cystic fibrosis: how a bacterium manipulates its host to eradicate an opponent

   The main cause of death in patients suffering from cystic fibrosis is respiratory infection caused by different bacterial populations, which vary according to the age of the patient. Scientists at the Institut Pasteur and Inserm have identified a novel mechanism used by the Pseudomonas aeruginosa bacterium to hijack the immune system of its host in order to eradicate another bacterium,...

2. News | 2014.10.13

   Randomized controlled trials for Ebola: practical and ethical issues

   This article, published in The Lancet Journal on 10th, October 2014 deals with the ethics and practice of randomized controlled trials in the case of Ebola hemorrhagic fever epidemic. In the randomized trials patients are divided into different groups receiving various treatments, the distribution between the groups being formed by drawing of lots (also called randomization) compared to a...

3. News | 2014.10.16

   Ebola & mobile technology: battling epidemics with big data

   Thursday, October. 16th, 2014 the Institut Pasteur in Paris welcomed the “Académie Diplomatique Internationale” for a briefings on new analytical methods solving critical gaps in global public health. Flowminder made a presentation on methods consisting to use anonymized mobile phone network data with the aim to improve operational decision making in a range of areas including...

4. News | 2014.10.13

   Human papillomavirus linked to auto-immune disease

   Erosive oral lichen planus (OLP) is an auto-immune disease affecting skin and mucous membranes which results in an abnormal immune response against mucocutaneous cells. Today, scientists have proven that the immune cells involved in OLP are the same as those activated during an immune response to human papillomavirus (type HPV-16). This suggests a link between OLP and HPV.

5. News | 2014.10.22

   Blood Ebola survivors tested as short-term treatment option

   An international research consortium will assess whether treatment with antibodies in the blood of Ebola survivors could help infected patients to fight off the disease. If proven effective, this straightforward intervention could be scaled up in the short term and provide an urgently needed treatment option for patients in West Africa.

6. News | 2014.10.27

   A bioinformatics tool to monitor the resistance and virulence of Klebsiella pneumoniae bacteria

   By sequencing the genomes of several strains of Klebsiella pneumoniae, scientists have revealed their genetic profile and pinpointed the genes responsible for their multiple antibiotic resistance and virulence. They have used these results to compile a database for the scientific community, providing high-resolution genetic fingerprints and information on genes of medical importance. This should...

7. News | 2013.06.17

   Chikungunya : discovery of a human-specific factor involved in the virus replication

   Chikungunya : discovery of a human-specific factor involved in the virus replication

8. News | 2013.04.21

   The loss of François Jacob, a prominent name in molecular biology

   A former member of the French Second Armored Division and Companion of the Liberation, François Jacob risked his life to defend the fundamental values of democracy and freedom. He was a brilliant scientist who spent his entire career at the Institut Pasteur and who inspired many researchers who followed in his tracks. François Jacob never missed an opportunity to demonstrate his commitment...

9. News | 2013.04.16

   Legionellosis: unique host cell reprogramming induced by the bacterial pathogen Legionella pneumophila

   Scientists at the Institut Pasteur, the CNRS, the Institut Curie and Inserm have identified a unique mechanism that enables the bacterial pathogen Legionella pneumophila (the causative agent of Legionnaires’ disease or legionellosis) to "reprogram" the gene expression of the eukaryotic cells that it infects. This mechanism, which has never been observed before, facilitates the...

10. News | 2013.04.15

    Atomic-level characterization of the effects of alcohol on a major player of the central nervous system

    Scientists at the Institut Pasteur, the CNRS and the University of Texas have been able to observe at atomic-level the effects of ethanol (the alcohol present in alcoholic beverages) on central nervous system receptors. They have identified five ethanol binding sites in a mutant of a bacterial analog of nicotinic receptors, and have determined how the binding of ethanol stimulates receptor...

Pages