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News | 2013.04.16
Legionellosis: unique host cell reprogramming induced by the bacterial pathogen Legionella pneumophila
Scientists at the Institut Pasteur, the CNRS, the Institut Curie and Inserm have identified a unique mechanism that enables the bacterial pathogen Legionella pneumophila (the causative agent of Legionnaires’ disease or legionellosis) to "reprogram" the gene expression of the eukaryotic cells that it infects. This mechanism, which has never been observed before, facilitates the...
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News | 2013.04.15
Atomic-level characterization of the effects of alcohol on a major player of the central nervous system
Scientists at the Institut Pasteur, the CNRS and the University of Texas have been able to observe at atomic-level the effects of ethanol (the alcohol present in alcoholic beverages) on central nervous system receptors. They have identified five ethanol binding sites in a mutant of a bacterial analog of nicotinic receptors, and have determined how the binding of ethanol stimulates receptor...
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News | 2013.04.10
Even in low doses, antibiotics can contribute to the emergence of multi-resistant bacteria
Scientists at the Institut Pasteur and CNRS have shown that the use of low dose antibiotics can increase the emergence of resistance among pathogenic bacteria. They have observed that a low concentration of antibiotics is enough to activate a stress response in these bacteria. This response, known as "SOS", leads to the acquisition of resistance genes via two separate pathways. This...
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News | 2013.03.17
Buruli Ulcer: Mechanism Behind Tissue Erosion Revealed
Scientists at the Pasteur Institute in Paris and the CNRS (French National Center for Scientific Research), in collaboration with the Universities of Basel (Switzerland) and Cambridge (UK) have identified the mechanism underlying the formation of Buruli ulcers caused by the bacterium Mycobacterium ulcerans. Their discovery opens avenues for the development of novel therapeutic approaches for...
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News | 2013.03.13
Aids : 14 adult patients in long term functional remission of HIV seven years after being taken off early antiretroviral treatment
Newly published scientific study describes 14 adult patients in long term functional remission of HIV seven years after being taken off early antiretroviral treatment. The Anrs EP 47`VISCONTI´ cohort confirms on a larger and durable scale what the Mississippi `functionally cured´ baby indicated – that early therapeutic intervention may be instrumental in HIV remission and has...
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News | 2013.06.30
Retracing the evolutionary history and emergence of tuberculosis
In association with CEA-Genoscope and the Sanger Institute, scientists at the Institut Pasteur in Paris, the CNRS, INSERM, the Institut Pasteur of Lille, and Université Lille 2 have recently determined the origin of the emergence of the Mycobacterium tuberculosis bacterium, the main causative agent of tuberculosis. Researchers have also provided insights into its evolutionary success. They have...
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News | 2013.02.06
Treatment of Cutaneous Leishmaniasis: Study of Phase III Shows Antibiotic Cream Has High Cure Rate, Few Side Effects
An international research partnership from Tunisia, France and the United States has demonstrated a high cure rate and remarkably few side effects in treating patients with cutaneous leishmaniasis (CL) with an antibiotic cream. CL is a parasitic disease that causes disfiguring lesions and affects 1.5 million people worldwide annually, including the socio-economically disadvantaged in the...
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News | 2013.01.06
Retracing the evolutionary history and emergence of tuberculosis
In association with CEA-Genoscope and the Sanger Institute, scientists at the Institut Pasteur in Paris, the CNRS, INSERM, the Institut Pasteur of Lille, and Université Lille 2 have recently determined the origin of the emergence of the Mycobacterium tuberculosis bacterium, the main causative agent of tuberculosis. Researchers have also provided insights into its evolutionary success. They have...
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Page avancée | 2016.10.07
Scientific and artistic collections. Letters and manuscripts
Scientific and artistic collections. Letters and manuscripts
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Document de presse | 2016.10.21
Africans and Europeans have genetically different immune systems... and Neanderthals had something to do with it
The immune system can be highly active in some people but much less effective in others. This has major implications for the protection of the organism against pathogens – but what is the reason for these differences? To lay the foundations for the establishment of personalized medicine, we need to dissect the factors that affect our response to viral and bacterial infections so that we can...
