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News | 2022.02.23
What is long COVID ?
In May 2020, while the first wave of the COVID-19 outbreak was coming to an end in France, initial reports emerged of patients with some persistent symptoms several weeks or months post-infection. This phenomenon, now referred to as "long COVID" (or post-COVID-19 syndrome) affects over 20% of patients after 5 weeks and over 10% of patients after 3 months. Serious or severe forms of initial SARS-...
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News | 2021.10.05
Conserving microbiota to tackle antibiotic resistance
Our microbiota provide an additional means of fighting off infections but can be adversely affected by antibiotic therapy. A study modeling microbial populations and their response to drugs offers potential for improving our understanding of antibiotic resistance and tackling it more effectively.
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News | 2021.11.12
Virtual reality effective in preoperative planning for breast cancer surgery
A recent study evaluates the benefits of 3D visualization for surgeons analyzing MRI breast images. Based on the innovative DIVA technology, developed jointly by the Institut Pasteur and the Institut Curie, a new software application gives surgeons immersive 3D visualizations of MRI images, enabling them to analyze situations more quickly and determine the best approach to take.
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News | 2021.10.18
Cancer: the role of substrate rigidity in tumor migration
Among the characteristics defining our constituent organs are their different rigidities. Changes in these physical properties occur during tumor development. Tumors use the rigidity of their surrounding environment to facilitate their migration to neighboring tissue, which in turn facilitates tumor invasion and metastasis. Scientists at the Institut Pasteur have identified a new element enabling...
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News | 2021.11.17
How does the Kaposi’s sarcoma herpesvirus enter the cell? A new understanding
The Kaposi's sarcoma herpesvirus causes skin cancers, especially in immunocompromised people. A recent study offers new modellings of one of the virus’ a surface proteins, and its receptor, on human cells.
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News | 2021.12.07
Virtual reality helps explore how the brain initiates movements
To escape predators or to acquire rewards, animals need to anticipate movements. How does the brain accomplish this task? Scientists at the Institut Pasteur have recorded the activity of neurons in the frontal cortex of mice that were trained to run towards rewards. They find that seconds before the mice start running, neurons show increasing “ramps” of activity.
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News | 2021.12.14
A better picture of Listeria reservoirs and global spread
Two recently published studies by Institut Pasteur researchers and collaborators shed light onto the ecology and evolution of the bacterial pathogen Listeria monocytogenes. These publications highlight the high prevalence of faecal carriage of the pathogen in asymptomatic hosts, its dependence on the microbiota, and the global spread of its main clinical clone.
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News | 2021.12.21
New insights into the adaptation mechanisms of Leishmania parasites
Parasites of the genus Leishmania show important genomic instability, which these pathogens use to adapt to their environment. A study by Institut Pasteur researchers shows that Leishmania exploits non-coding RNAs to mitigate toxic effects of genome instability by post-transcriptional regulation and the establishment of specialized ribosomes.
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News | 2022.02.01
CoronaFISH: a new method for studying SARS-CoV-2 and detecting its presence in the body
The COVID-19 pandemic, which has afflicted the world for more than two years, is caused by SARS-CoV-2. The genome of this respiratory virus is composed of a single strand of RNA, a molecule similar to DNA that enables the virus to replicate in the body. Scientists from the Institut Pasteur, Inserm and the Paris Public Hospital Network (AP-HP) have developed a new method, CoronaFISH, to observe...
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News | 2022.02.16
Understanding resistance in HIV controller patients: how their antiviral CD4+ T cells are protected from infection
Some rare HIV-infected patients are able to keep the viral load low enough not to require treatment. A study by researchers at the Pasteur Institute and collaborators shows that these patient CD4+ T cells block a receptor that is important for HIV entry.
