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Fiche maladie | 2019.06.25
Lassa fever
Lassa fever is an acute viral disease belonging to the category of viral hemorrhagic fevers, similar to Ebola. It is mainly found in West Africa and is caused by the Lassa virus, which is transmitted to humans through contact with infected rodents. Although many cases of infection are asymptomatic, the disease may be severe and potentially fatal.
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News | 2019.07.01
Successful second international medical entomology course in Vientiane, Laos
The second international medical entomology course took place in Vientiane, at the Institut Pasteur du Laos, for two weeks from June 10 to 22, 2019. The course is funded by the Pasteur International Network Association and held on an alternating basis with the Insect Vectors and Transmission of Pathogenic Agents (IVTPA) course at the Institut Pasteur in Paris. The next IVTPA course will take...
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News | 2019.07.04
An innovative tool to study psychiatric or infectious diseases
At the Cap'CARNOT event on June 27, 2019 in Paris, the Pasteur Microbes and Health Carnot Institute, composed of several Institut Pasteur departments and technological platforms, presented a tool based on artificial intelligence that can be used to monitor the behavior of groups of mice in real time and characterize their social interactions. The Cap'CARNOT event on June 27, 2019 in Paris....
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Document de presse | 2019.07.10
Anaphylactic shock: IgG antibodies and neutrophils play an unexpected role
Anaphylactic shock, an exacerbated allergic reaction that can prove fatal, is sometimes caused by the use of drugs during surgery. In most of these extreme reactions, evidence can be provided that patients have anti-drug antibodies of the IgE class. In 10 to 20% of anaphylactic cases evidence for the involvement of anti-drug IgE is lacking. Anti-drug IgE enable activation of mast cells and...
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Document de presse | 2019.07.11
High-risk pregnancy: the interferon effect
Discovery of a cellular mechanism involved in abnormal placental development during some high-risk pregnancies.High-risk pregnancies occur frequently and may be caused by various factors. It is estimated that 10 to 20% of pregnant women miscarry during their first trimester of pregnancy. Slow fetal growth may also arise as a result of maternal infection with certain microbes, parasites or viruses...
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News | 2019.07.08
High-level microscopy unveils bacteria’s adaptation mechanisms
Microorganisms are constantly challenged by a variety of environmental stresses. In many bacteria, the stressosome, a key inducer of the stress response is a very large machine that responds to diverse environmental changes. However, how the stressosome transmits stress signals from the environment has remained elusive. Thanks to a high-resolution microscope Titan KriosTM, researchers from the...
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Article | 2019.07.09
Cours internationaux - 2019
TITLEORGANIZERINSTITUTEDURATION DATECOURSE PLACEAtelier NGS : Epidémiologie génomique, microbiome et métagénomique pour l'Afrique et l'Océan IndienJean-Marc COLLARDInstitut Pasteur Madagascar7 daysTo Be DefinedInstitut Pasteur MadagascarSystèmes d'information géographique appliquées à l'épidémiologie : Introduction au logiciel QGIS 2. Analyses multicritères spacialisées : Application en...
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Document de presse | 2019.07.12
HIV: reprogramming cells to control infection
Cells from the rare individuals who naturally control HIV infection have been the focus of investigation for nearly 15 years with the aim of elucidating their specific features. Following research on the ANRS CO21 CODEX and CO6 PRIMO cohorts, scientists from the Institut Pasteur have described the characteristics of CD8 immune cells in these "HIV controller" subjects. The unique antiviral power...
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Article | 2019.07.11
Department of Computational Biology
We live at a time when biology is producing vast reams of data, which can only be deciphered using mathematical modeling, statistics and computing, providing answers to a wide variety of biological and medical questions. The Department of Computational Biology was set up to analyze and model these data, and develop new analytical methods tailored to new data acquisition technologies (sequencing,...
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News | 2019.07.16
Immature heart cells persist in the adult heart and react to infarction
Cardiovascular diseases are a major cause of mortality and morbidity worldwide. After myocardial infarction, heart cells (or cardiomyocytes) die and are replaced by fibrotic tissue leading to impaired cardiac function. The assessment of the regenerative capacity of the heart has always been compromised by the lack of signatures to characterize cardiomyocytes. Researchers from the Institut Pasteur...
