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News | 2019.07.25
Aimee Wessel and Raphaël Tomasi win the i-Lab award for their MultiScreen project
On July 4, the i-Lab innovation competition unveiled the names of its 75 winners, which this year included Aimee Wessel and Raphaël Tomasi from the Physical Microfluidics and Bioengineering Unit (Institut Pasteur/École Polytechnique/CNRS). Sponsored by the French Ministry of Higher Education, Research and Innovation and organized in partnership with Bpifrance Financement, i-Lab is France's...
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News | 2019.08.28
The 2018 Institut Pasteur Annual Report is available
The year 2018 has been exceptional in several ways. It was marked by the celebration of the 130th anniversary of the Institut Pasteur and the arrival of a new President. The adoption of its 2019-2023 Strategic Plan offers a new ambition for the institute, and recalls that human health is at the heart of its mission. "The Institut Pasteur in 2018" video. Copyright: Institut Pasteur / La...
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Document de presse | 2019.08.12
Cervical cancer: New test enhances ability to predict risk
The Journal of Molecular Diagnostics and the Institut Pasteur report that a new test enhances ability to predict risk of developing cervical cancer in human papillomavirus (HPV)-positive women. This two-fold test is capable of detecting and determining the type of HPV infection as well as the likelihood of progressing to cancer.Philadelphia, August 12, 2019 – Ninety-nine percent of cervical...
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Report | 2019.09.02
French Bioethics Law: an original participatory approach for the National Bioethics Consultation
A bioethics bill was tabled at the French Council of Ministers on Wednesday July 24, 2019. As the bill is examined by the French Parliament in September, it is a good opportunity to look at how this process came about and examine the contribution made by the French National Consultative Ethics Committee (CCNE). The CCNE Chairman, Professor Jean-François Delfraissy, came to the Institut Pasteur on...
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News | 2019.09.06
Whooping cough: elucidation of a critical stage in the action of the CyaA toxin
Scientists from the Institut Pasteur are investigating CyaA, one of the major toxins of Bordetella pertussis. This bacterium is responsible for whooping cough, a disease that is currently on the rise. Acylation is a biochemical reaction in which an acyl chain is added to a molecule. It was already known that the CyaA protein was acylated in Bordetella pertussis. The scientists used a combination...
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News | 2019.09.09
Depression: the key role of neuroinflammation
Depression is a complex multifactorial condition whose underlying mechanisms have still not been elucidated. Available treatments are therefore far from effective, and it is estimated that 30% of patients are resistant to conventional treatment. Scientists from the Institut Pasteur, in collaboration with teams from Sainte-Anne Hospital, have shed light on the role of brain inflammation as a...
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News | 2019.09.11
Phagotherapy: a support for the work on bacteriophages of a Franco-American team (Institut Pasteur and Georgia Tech)
An interdisciplinary team of researchers at the Institut Pasteur and the Georgia Institute of Technology has received a $2.5 million National Institutes of Health (NIH) grant to study phage therapy. This project aims to deepen the fundamental knowledge and the clinical potential of bacteria-killing viruses – also called bacteriophage, or phage –, to treat antibiotic-resistant infection.Over the...
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Document de presse | 2019.09.10
Discovery of a new ribosomopathy in humans that results in a lack of testis-determination or testicular regression
Sex determination is the process whereby an organism becomes male or female. A multinational consortium, led by Institut Pasteur scientists, has made a breakthrough in understanding the genetics of sex determination in humans. They have discovered that DHX37, a gene highly conserved during evolution and until now only known for its role in ribosome biogenesis, is involved in both determining and...
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Portrait | 2019.09.17
Laure Bally-Cuif, neurogeneticist like a fish in water
Laure Bally-Cuif leads the Zebrafish Neurogenetics Unit at the Institut Pasteur. The model for her research is a little fish, mutant forms of which can remain transparent until adulthood – an important characteristic for observing the many cells involved in brain development.Laure Bally-Cuif was born in Lyon and grew up in a working-class household. At school, she was a talented student and...
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Portrait | 2018.05.29
Fani Koukouli: A young researcher's odyssey to the inner depths of the brain
Fani Koukouli's decision to pursue a career researching the workings of the brain and identifying new molecules to tackle diseases such as schizophrenia and Alzheimer's did not happen by chance. Fani grew up and began her studies in Greece, in the port city of Thessaloniki on the Aegean Sea. She remembers being fascinated by pictures of scientists in her primary school textbooks. But then an...
