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News | 2019.11.07
Parkinson's: new discoveries about nanotubes, transporters of toxic proteins
We now know that neurodegenerative diseases are caused by the aggregation of "misfolded" proteins in the brain. These proteins, which are toxic for neurons, spread from cell to cell through tiny tunnels, known as nanotubes. After imaging their structure in detail, (1) scientists in the Institut Pasteur's Membrane Traffic and Pathogenesis Unit, directed by Chiara Zurzolo, are now investigating the...
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News | 2019.11.08
Gut microbiota: surprising interactions between pathogenic and commensal bacteria
In achieving a state of equilibrium in the body, the billions of microbes that form assemblies known as microbiota at various sites including the gut, the skin and the oral cavity play an important role. The absence of microbiota results in increased exposure to some diseases. Scientists from the Bacteria-Cell Interactions Unit at the Institut Pasteur, in collaboration with INRA, Inserm...
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Document de presse | 2019.11.12
Gut microbiota imbalance promotes the onset of colorectal cancer
The gastroenterology team at Henri-Mondor AP-HP Hospital and University Paris-Est Créteil, led by Professor Iradj Sobhani, together with teams from Inserm and the Institut Pasteur Molecular Microbial Pathogenesis Unit (U1202), led by Professor Philippe Sansonetti – holder of the Microbiology and Infectious Diseases Chair at the Collège de France –, have demonstrated that an imbalance in the gut...
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Portrait | 2019.11.18
Lluis Quintana-Murci: discovering the world and humankind
Lluis Quintana-Murci is a scientist specializing in human genetics, with a particular focus on population genetics. His fascinating research tells an amazing story – our story, the story of humanity through time and in all its stunning diversity. Lluis was delighted to talk to us about his background and his passion for his work.Lluis was born in 1970 in Palma de Mallorca in Spain. As a child, he...
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News | 2019.11.18
Chaos in ageing skeletal muscle stem cells
Faithful to the Pasteurian mission that aims to tackle human public health issues, the Institut Pasteur is involved in research on ageing. Seeking understand the decline in function of tissues in organisms, researchers from the Stem Cells and Development unit at Institut Pasteur made a discovery on the still unknown mechanisms of the epigenetic clock in stem cells.Epigenetic modifications have...
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Report | 2019.11.25
Managing outbreaks more effectively
Disease outbreaks are unpredictable and often deadly. Wherever they occur on the planet, we are all potentially at risk: in our era of globalized air travel, a microbe can make it round the world in less than 24 hours. Alongside outbreaks of well-established diseases such as influenza, yellow fever, plague, cholera and measles, we are also seeing many outbreaks caused by more "recent" pathogens...
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Fiche maladie | 2019.10.02
Influenza
Influenza is a contagious respiratory infection caused by influenza viruses, which are unique due to their vast genetic variability. It is a public health issue because of the seasonal outbreaks that affect 2 to 6 million people in France every winter, with influenza-associated excess mortality estimated at approximately 10,000 deaths, mainly in vulnerable individuals. The pandemic risk...
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News | 2019.11.20
The Institut Pasteur hosts an OIE (World Organization for Animal Health) collaborating center
The Institut Pasteur is now home to the World Organization for Animal Health Collaborating Center for the detection and identification in humans of emerging animal pathogens and development of tools for their diagnoses. It is hosted by the Environment and Infectious Risks Unit (led by Jean-Claude Manuguerra), with the Laboratory for Urgent Response to Biological Threats and the Pathogen Discovery...
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News | 2019.11.22
2018 Activity Report for the Pasteur Microbes and Health Carnot Institute
The Activity Report for the Pasteur Microbes and Health Carnot Institute has now been published. It looks back at the main activities carried out in 2018, in synergy with the Institut Pasteur's Research Applications and Industrial Relations Department (DARRI). These activities are in line with the Institut Pasteur's 2019-2023 Strategic Plan.The Pasteur Microbes and Health (Pasteur MS) Carnot...
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News | 2019.11.26
Artificial intelligence: a new platform for the biomedical community
Artificial intelligence methods such as deep learning are enabling breakthrough advances in biomedical data analysis. From medical diagnosis and DNA sequence analysis to augmented microscopy and molecular design, the scope of applications for artificial intelligence is constantly expanding and drawing on ever larger datasets. However, most research studies based on deep learning do not enable...
