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Document de presse | 2013.04.10
Even in low doses, antibiotics can contribute to the emergence of multi-resistant bacteria
Scientists at the Institut Pasteur and CNRS have shown that the use of low dose antibiotics can increase the emergence of resistance among pathogenic bacteria. They have observed that a low concentration of antibiotics is enough to activate a stress response in these bacteria. This response, known as "SOS", leads to the acquisition of resistance genes via two separate pathways. This...
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Document de presse | 2013.05.05
Chikungunya : discovery of a human-specific factor involved in the virus replication
Scientists from the Institut Pasteur, Inserm and CNRS, have identified a human-specific factor involved in the replication of Chikungunya virus which accounts for the species specificity of this virus. Chikungunya virus is an emerging virus that in 2005 caused, for the first time, an outbreak in La Réunion island, a French overseas district where more than 30% of the population was infected, and...
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Document de presse | 2012.05.13
Learning and memory: the role of neo-neurons revealed
Researchers at the Institut Pasteur and the CNRS have recently identified in mice the role played by neo-neurons formed in the adult brain. By using selective stimulation the researchers were able to show that these neo-neurons increase the ability to learn and memorize difficult cognitive tasks. This newly discovered characteristic of neo-neurons to assimilate complex information could open up...
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Document de presse | 2012.02.26
Four Prestigious Awards to Support Innovative Biomedical Research
Sanofi (EURONEXT: SAN and NYSE: SNY) and the Institut Pasteur announced today the creation of the Sanofi-Institut Pasteur Awards to encourage scientific excellence in the service of health. Four hundred and eighty thousand euro (480,000 €) will support four innovative research projects demonstrating real progress in the life sciences and providing answers to major healthcare problems, more...
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Document de presse | 2011.12.18
Genetic diversity: crucial for our survival in many ways
Thanks to the sequencing of the 27 known human interferon genes, researchers from the Institut Pasteur and the CNRS reconstruct the genetic history of these proteins so central for our immune system, and put forward potentially innovative ways to improve the clinical use of interferons in the treatment of pathologies such as Hepatitis C, multiple sclerosis, and some cancers. These results are...
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Document de presse | 2011.10.02
Cerebral malaria, allergy-like mechanisms to blame
Researchers from the Institut Pasteur and the CNRS, in collaboration with Inserm and the Université Paris Diderot, have demonstrated the role an inflammatory reaction plays in the development of cerebral malaria in mice. Cerebral malaria is one of the most severe forms of malaria primarily affecting young children. If confirmed in humans, this discovery would pave the way for new therapeutic...
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Document de presse | 2011.09.12
The first human model for neurodegenerative Sanfilippo syndrome
Researchers from the Institut Pasteur and Inserm, in collaboration with the Centre de Biologie Cellulaire in Lyon, have obtained the first human neuron model for Sanfilippo syndrome, an incurable neurodegenerative disorder that occurs in children. This model is the tool of choice for studying the cellular mechanisms at the root of this disease as well as for identifying therapeutic options....
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Document de presse | 2011.05.15
Graft rejection at the cellular level filmed in 3D
Using a new and original in vivo imaging technique enabling real-time, in-depth, cellular immune response mechanism investigation in animals, researchers from the Institut Pasteur and Inserm have been the first to observe the process of graft rejection. Observing this "cellular choreography" has most notably proven the existence of a mechanism that contributes to the immune reaction...
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Document de presse | 2011.03.31
AREVA Foundation and Institut Pasteur sign a new partnership agreement for Aids research
AREVA Foundation continues to fight Aids alongside the Institut Pasteur in 2011. Two new Institute teams will benefit from the continuing partnership: • the team led by Professor Olivier Schwartz, who directs the Virus and Immunity Research Unit • the team of Dr. Michaela Müller of the Retroviral Infection Regulation Unit directed by Professor Barré-Sinoussi, Nobel Prize in Medicine....
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Document de presse | 2011.01.19
3D structure leads to first decoding of mechanism of action of general anesthetics
Two teams from the Institut Pasteur in association with the French National Center for Scientific Research (CNRS) have published in the journal Nature the three-dimensional structure of two general anesthetics bound to their membrane receptor. This research provides the first atomic-resolution structures of general anesthetics which can be used to understand their action mechanism, a mechanism...