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Document de presse | 2017.07.20
Gene therapy: first results in children with Sanfilippo B syndrome
On July 13, 2017, the journal Lancet Neurology published the results of a gene therapy trial conducted in four children with Sanfilippo type B syndrome (also known as MPS IIIB). This trial is the achievement of a two-decade partnership with financial support of AFM-Téléthon and the cooperation of the charity "Vaincre les Maladies Lysosomales" (VML). After monitoring of the treated children for 30...
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Article | 2017.10.13
Afribiota project: Childhood malnutrition
Malnutrition is a leading cause of child morbidity and mortality in low-income countries. The state of malnutrition is maintained by a chronic inflammation of the intestine observed in a large proportion of children living in unsanitary conditions. This syndrome called pediatric environmental enteropathy has so far been poorly studied. The Afribiota project aims to better characterize this...
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Document de presse | 2017.12.11
How Zika virus induces congenital microcephaly
A team of researchers from ZIKAlliance discovers a specific mechanism of the infectionEpidemiological studies show that in utero fetal infection with the Zika virus (ZIKV) may lead to microcephaly, an irreversible congenital malformation of the brain characterized by an incomplete development of the cerebral cortex. However, the mechanism of Zika virus-associated microcephaly remains unclear. An...
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News | 2018.04.16
Halima Maïnassara: from field investigator to director of CERMES in Niger
In February 2017, Dr Halima Maïnassara is the first woman from Niger to be appointed Director General of the Center for Medical and Health Research (CERMES) in Niamey. Physician, epidemiologist expert in meningitis, she started to work for this public institution, member of the Institut Pasteur International Network, in February 2005 as a field investigator.Since primary school, Halima Boubacar...
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Document de presse | 2018.06.14
HIV: “controller” patient research holds promise for cell therapy
Rare patients infected by HIV spontaneously control viral replication without antiretroviral therapy, and do not go on to develop AIDS. The ability of these patients, known as "HIV controllers", to limit HIV replication appears to result from a highly effective immune response. Scientists from the Pasteur Institute and Inserm, together with colleagues from Monash University, Melbourne, found that...
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News | 2018.07.02
Daniel Iffla-Osiris, a great 19th-century philanthropist and the Institut Pasteur's most generous donor
The square known as "Place Daniel Iffla-Osiris", at the junction of boulevard Haussmann and boulevard des Italiens in Paris, was officially opened on June 27, 2018. This inauguration is an ideal opportunity to look back on the story of Daniel Iffla-Osiris, one of the greatest philanthropists of the 19th century. At his death in 1907, he left behind the largest legacy ever received by the Institut...
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Document de presse | 2018.11.22
How bacteria invade us – Pascale Cossart honoured with 2018 Heinrich Wieland Prize
Professor Pascale Cossart of the Institut Pasteur in Paris will be honoured with the 2018 Heinrich Wieland Prize for her fundamental contributions to Molecular Infection Biology. Cossart’s innovative research has unravelled how pathogenic bacteria, in particular food-borne Listeria, enter human cells, use the host cells’ own mechanisms to do so, and trick and evade the immune system. Her...
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Fiche maladie | 2019.06.25
Lassa fever
Lassa fever is an acute viral disease belonging to the category of viral hemorrhagic fevers, similar to Ebola. It is mainly found in West Africa and is caused by the Lassa virus, which is transmitted to humans through contact with infected rodents. Although many cases of infection are asymptomatic, the disease may be severe and potentially fatal.
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Portrait | 2018.12.04
For Asier Sáez-Cirión, research is an incurable passion
It was 35 years ago that the HIV-1 virus, responsible for AIDS, was first isolated by scientists at the Institut Pasteur. While many lives have been saved by antiretroviral therapy, there is currently no treatment that fully eliminates the virus from the body, and the search for a vaccine goes on. These challenges are driving the research of a number of scientists at the Institut Pasteur,...
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News | 2019.10.25
Exhibition in honor of Jules Bordet at the Université libre de Bruxelles
On October 8, 2019, the Université libre de Bruxelles inaugurated an exhibition entitled "100th anniversary of a Nobel Prize – Jules Bordet". Developed in collaboration with the Institut Pasteur, this exhibition pays tribute to Institut Pasteur scientist Jules Bordet, who was awarded the 1919 Nobel Prize in Physiology or Medicine for his work on immunity. The exhibition will run until December 21...