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Article | 2020.10.14
Covid-19: A vaccine candidate using a lentiviral vector
This vaccine candidate for the SARS-CoV-2 virus, designed for nasal administration, demonstrated intense protection and extremely high production of antibodies and cytotoxic cell responses in preclinical trials.
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Document de presse | 2020.10.16
Team of international scientists identify common vulnerabilities across SARS-CoV-2, SARS-CoV-1 and MERS coronaviruses
Driven by Molecular Insights, Massive Analysis of Medical Records from ~740,000 SARS-CoV-2 Patients Reveal Treatment Regimens for Current, and Potential Future, Viral Pandemics. Published on October 15, 2020, in Science. In a study published online in Science, an international team of almost 200 researchers from 14 leading institutions in six countries, including France with the...
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News | 2020.10.22
Coronavirus: Institut Pasteur warns against false information circulating on social media
-ENGLISH VERSION COMING SOON-Mis à jour le 20 mars 2023.En 2020-2021, lorsque la pandémie de Covid-19 était à son pic, de nombreuses informations circulaient dans les médias, sur les réseaux sociaux, les messageries instantanées, etc. Ces messages ont pu parfois contenir des informations erronées ou s’appuyant sur des propos attribués à tort à des chercheurs de l’Institut Pasteur à...
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News | 2020.11.09
Leptospirosis: elucidation of a new gene regulation mechanism based on DNA modification
Pathogenic Leptospira are responsible for leptospirosis, a disease that occurs in many world regions. Leptospirosis is a zoonosis, in other words it affects wild or domestic animals but may be transmitted to humans. A partnership between the Institut Pasteur (Paris) and the INRS Armand-Frappier Santé Biotechnologie Research Center has led to the discovery of a novel mechanism for virulence...
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News | 2020.11.12
Alzheimer: how endogenously formed Tau aggregates fail to be degraded
Alzheimer's disease is a progressive neurodegenerative disorder that mainly affects memory, but also other cognitive functions linked to knowledge and involving language, logical thought and learning capacity. This disease generally leads to loss of independence for sufferers. It is one of the leading causes of disability and dependency in elderly people. There is currently no cure for the...
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News | 2020.11.26
Urinary tract infections: the mechanisms behind the lack of immune memory in many patients
Urinary tract infections (UTI) are a group of infectious diseases that predominantly impact healthy adult women, although they can also cause serious disease in men. They are the second most prevalent infection after respiratory infections*. The immune response to UTI is still not well-understood, and a better understanding could help lessen the use of antibiotics for this common infection....
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Document de presse | 2020.12.28
COVID-19: optimizing surveillance in long-term care facilities
Throughout the world, long-term care facilities have been high-risk sites for virus spread since the emergence of the COVID-19 epidemic. In this context, the capacity for timely surveillance and control of case numbers is essential in such facilities. Scientists at the Institut Pasteur have joined forces with the University of Versailles-Saint-Quentin-en-Yvelines, Inserm, and the National...
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Document de presse | 2021.01.19
COVID-19: a lentiviral vaccine candidate for intranasal administration provides sterilizing protection in animal models
Scientists from the Institut Pasteur-TheraVectys Joint Laboratory recently published in Cell Host & Microbe1 the results of tests, in two preclinical models, of a COVID-19 vaccine candidate using a lentiviral vector administered by nasal route. Their study demonstrates that the vaccine candidate induces antibody response with strong neutralizing activity against SARS-CoV-2, as well as...
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Document de presse | 2021.01.25
COVID-19: progress update on the Institut Pasteur's scientific response and vaccine candidate research programs
Since early 2020, the Institut Pasteur has been engaged in research in several of its areas of scientific expertise, including virology, diagnostics, pathophysiology, epidemiology, modeling, therapeutic research and vaccine research. A number of research programs to find a vaccine for SARS-CoV-2, the virus responsible for the COVID-19 epidemic, are under way. In light of the intermediate results...
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News | 2021.02.15
Discovery of messenger RNA in 1961
Since the beginning of the COVID-19 pandemic, words that just a year ago would have been the preserve of scientists have entered everyday language. One example is PCR, used for diagnostic tests. Another term that was once unfamiliar and is now on everyone's lips is messenger RNA, the miraculous molecule that has led to vaccines being administered to the general population less than a year after...