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Document de presse | 2011.01.19
3D structure leads to first decoding of mechanism of action of general anesthetics
Two teams from the Institut Pasteur in association with the French National Center for Scientific Research (CNRS) have published in the journal Nature the three-dimensional structure of two general anesthetics bound to their membrane receptor. This research provides the first atomic-resolution structures of general anesthetics which can be used to understand their action mechanism, a mechanism...
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Document de presse | 2012.01.22
Launching of the Institut Pasteur in Laos
Today, Monday January 23, 2012, in Vientiane the launch of the Institut Pasteur in Laos was officiated by the Lao Minister of Public Health, professor Som Ock Kingsadat and the President of the Institut Pasteur in Paris, professor Alice Dautry. This is the Institut Pasteur International Network’s 32nd institute. The new research center for infectious and parasitic diseases aims to reduce...
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Document de presse | 2012.02.09
Newly characterized dengue virus antibody shows promise
Research teams from the Institut Pasteur, the CNRS, and Inserm have recently characterized the structure and mechanism of action of an antibody that successfully neutralizes all four strains of the dengue virus in mice models. Their groundbreaking work represents major progress for research efforts that hope to develop an effective vaccine to combat this disease. This study was published February...
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Document de presse | 2012.11.13
The Institut Pasteur inaugurates its new center for research on emerging diseases at a ceremony attended by French President François Hollande
On November 14, 2012, Professor Alice Dautry, President of the Institut Pasteur, and Jean-Pierre Jouyet, Chairman of the Institut Pasteur Board of Directors, officially opened the Institut Pasteur’s research center for the study of emerging diseases at a ceremony attended by French President François Hollande. Paris, november 14, 2013 In recent decades, we have witnessed...
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Document de presse | 2013.02.06
Treatment of Cutaneous Leishmaniasis: Study of Phase III Shows Antibiotic Cream Has High Cure Rate, Few Side Effects
An international research partnership from Tunisia, France and the United States has demonstrated a high cure rate and remarkably few side effects in treating patients with cutaneous leishmaniasis (CL) with an antibiotic cream. CL is a parasitic disease that causes disfiguring lesions and affects 1.5 million people worldwide annually, including the socio-economically disadvantaged in the...
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Document de presse | 2013.03.17
Buruli Ulcer: Mechanism Behind Tissue Erosion Revealed
Scientists at the Pasteur Institute in Paris and the CNRS (French National Center for Scientific Research), in collaboration with the Universities of Basel (Switzerland) and Cambridge (UK) have identified the mechanism underlying the formation of Buruli ulcers caused by the bacterium Mycobacterium ulcerans. Their discovery opens avenues for the development of novel therapeutic approaches for...
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Document de presse | 2013.04.15
Atomic-level characterization of the effects of alcohol on a major player of the central nervous system
Scientists at the Institut Pasteur, the CNRS and the University of Texas have been able to observe at atomic-level the effects of ethanol (the alcohol present in alcoholic beverages) on central nervous system receptors. They have identified five ethanol binding sites in a mutant of a bacterial analog of nicotinic receptors, and have determined how the binding of ethanol stimulates receptor...
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News | 2013.04.15
Atomic-level characterization of the effects of alcohol on a major player of the central nervous system
Scientists at the Institut Pasteur, the CNRS and the University of Texas have been able to observe at atomic-level the effects of ethanol (the alcohol present in alcoholic beverages) on central nervous system receptors. They have identified five ethanol binding sites in a mutant of a bacterial analog of nicotinic receptors, and have determined how the binding of ethanol stimulates receptor...
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Document de presse | 2014.03.10
Inauguration of a Regional Platform of Research on transmissible and emerging infectious diseases in Southeast Asia (PRR-Asia)
Southeast Asia (SEA) is affected by emerging infectious diseases, and emerging outbreaks challenge the medical and scientific communities. The emergence of new diseases or their resistance to anti-microbial drugs in SEA is a complex mechanism which requires more interest on the diseases, on the condition of their emergence and on the diffusion of the causative agents. The study of infection...
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Document de presse | 2014.06.11
Predicting mutations that lead to epidemics
Using the 2005-2006 chikungunya virus epidemic that occurred in the Indian Ocean islands as a study model, researchers at the Pasteur Institute have succeeded in developing an approach that can predict the virus mutations most likely to emerge in the short-term, with strong epidemic potential. This work has strong implications for improving surveillance of ongoing epidemics and the potential to...