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News | 2023.03.03
"Hidden Face of Paris 2023" at the Institut Pasteur: a look back at the event
For the past ten years, the Hidden Face of Paris (Paris Face Cachée) event has been giving the public unique access to more than a hundred sites in the Greater Paris region over a 72-hour period. The idea is simple: members of the public sign up for an adventure based on an evocative title and description, without knowing who is organizing it or who they will meet. The venue is kept secret...
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Document de presse | 2023.02.20
HIV: third case in the world of probable cure after a bone marrow transplant
Forty years after the discovery of HIV in 1983 at the Institut Pasteur, 38.4 million people were living with the virus worldwide in 2021.[1] Only two cases of people being cured had previously been described: the Berlin patient in 2009 and the London patient in 2019. The IciStem consortium, whose members include Asier Sáez-Cirión's team at the Institut Pasteur, in collaboration with Düsseldorf...
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Portrait | 2023.02.10
Caroline Demangel – an ambitious and enterprising scientist
Finding her path, making meaningful choices and daring to take the initiative – these are the principles that have guided Caroline Demangel through her career. In the demanding and competitive field of science, she has trusted her aspirations and risen to new challenges. In 2021, the scientist and her team revealed a new therapeutic target for bone marrow cancer.
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Document de presse | 2022.12.20
Identification of a new neural pathway essential for refining odor perception
In the brain, sensory messages are processed by neurons that send the information collected by the sensory organ to the different structures of the brain. At each stage of integration, the activity of these neurons is controlled by interneurons that exert local inhibition in order to direct and modulate the neural messages. This type of circuit forms the classical architecture of the sensory...
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News | 2022.08.24
ZIKAlliance project: Zika vector competence data reveals risks of outbreaks
A publication published this summer looks back at the contribution of the European ZIKAlliance project, launched in 2016 following the Zika epidemic in the Pacific Islands and America. A global analysis of the competence of potential vectors was carried out, the most comprehensive study of vector competence to date using the same protocols. This study reminds us that vector-borne diseases are...
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News | 2022.08.24
ILC3s: "gatekeeper" cells for intestinal immunity
The intestinal mucosa is a key site for interaction and exchange with the external environment. It is therefore under constant surveillance from the immune system. Using an animal model, scientists from the Institut Pasteur and Inserm discovered how a set of cells involved in innate immunity – group 3 innate lymphoid cells – help monitor and maintain this barrier.Our digestive tract contains...
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News | 2022.07.11
A snapshot of 2021's highlights
Following the release of the 2021 edition of the Institut Pasteur's Annual Report, here are some of the year's highlights. Twelve eventful months interspersed with highlightsmajor scientific breakthroughs and key events for the institute in all fields including COVID-19, cancer, neuroscience, genetics, vaccinology and antibiotic resistance.
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News | 2022.07.09
Conversation: capacity building to prepare for the future
Institut Pasteur Senior Executive Scientific Vice-President Christophe d'Enfert provides a brief, cross-disciplinary overview of 2021 covering capacity building, enhanced partnerships and future technologies.
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News | 2022.07.01
Monitoring and early warning: Pasteur Center in Cameroon plays an active role in the response to SARS-CoV-2 virus
As a first-line laboratory in the event of a health emergency, the Pasteur Center in Cameroon was naturally designated as a COVID-19 reference laboratory by the Cameroon health authorities in 2020. How did the Pasteur Center in Cameroon organize its response to this emerging novel virus at national level throughout the epidemic, and how is it monitoring the virus today?At the beginning of the...
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Document de presse | 2022.06.29
Rethinking the rabies vaccine
Rabies virus kills over 50,000 people each year. Although current rabies vaccines are effective, they do not offer lifelong protection and booster doses are required. Institut Pasteur scientists, in collaboration with researchers from La Jolla Institute for Immunology (LJI) in the United States, captured new high-resolution views of rabies virus, revealing potential vaccine targets. These...