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Document de presse | 2016.04.11
Malaria: a new route of access to the heart of the parasite
Scientists have just identified an Achilles heel in the parasite that causes malaria, by showing that its optimum development is dependent on its ability to expropriate RNA molecules in infected cells – a host-pathogen interaction that had never previously been observed. Although the precise function of this deviation remains mysterious, these findings open new perspectives for the targeted...
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Document de presse | 2016.04.25
How could Zika enter Europe?
Researchers at the Institut Pasteur have assessed the transmission potential of four populations of Aedes mosquitoes in circulation on the island of Madeira and southern France with a view to examining various possible scenarios for the introduction of Zika virus to Europe. Their work suggests that the Aedes aegypti mosquito present in Madeira is more likely to promote local transmission of Zika...
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Document de presse | 2016.05.12
Meningococcal disease: identification of a sexually transmitted variant
A study from the University of Würzburg (Germany) and the Institut Pasteur (France) elucidates the mechanisms of the emergence of an outbreak of meningococcal disease in men who have sex with men (MSM). These results are published in the open access journal PLOS ONE. Neisseria meningitidis during adhesion and invasion of epithelial cells. © Institut PasteurMeningococcal disease...
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Document de presse | 2016.05.13
CNES and Institut Pasteur sign framework cooperation agreement - Space serving epidemic research
Monday 9 May at the Institut Pasteur in Paris, CNES President Jean-Yves Le Gall and the institute’s Director General Christian Bréchot signed a framework cooperation agreement on space serving epidemic research that aims to develop synergies between the two organizations’ missions and talents in their respective areas of excellence.Monday 9 May at the Institut...
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Document de presse | 2016.05.18
HIV: Identification of key immune response receptors in patients spontaneously controlling infection
A small number of patients infected by HIV spontaneously control viral replication without antiretroviral therapy, and do not develop the disease. The ability of these rare patients, known as "HIV controllers", to suppress HIV replication appears to be down to a highly effective immune response. Scientists from the Institut Pasteur and Inserm observed that CD4+ T immune cells in these...
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Document de presse | 2016.06.06
Identification of a therapeutic compound for a genetic form of autism spectrum disorders thanks to high throughput screening
A team of researchers from I-STEM laboratory (CECS / AFM-Telethon / Inserm), led by Alexandra Benchoua and Marc Peschanski, in collaboration with Prof. Thomas Bourgeron (Pasteur Institute / Paris Diderot University / CNRS) and Prof. Richard Delorme (Robert Debré Hospital / AP-HP), has highlighted the therapeutic potential of lithium in a patient with a rare form of autism spectrum disorder...
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Document de presse | 2016.06.23
Malaria - a mapping of artemisinin resistance confirms that resistance is confined to Southeast Asia and has not spread to sub-Saharan Africa
The first global mapping of artemisinin resistance (the KARMA study) has definitively confirmed that resistance to the main drug currently used in the treatment of Plasmodium falciparum malaria is for the moment confined to Southeast Asia and has not spread to sub–Saharan Africa. Led by researchers from both the Institut Pasteur in Paris and the Institut Pasteur in Cambodia, KARMA gathers a...
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Document de presse | 2016.06.23
Antibodies that are effective against both dengue and Zika viruses
Scientists from the Institut Pasteur and the CNRS[1], in collaboration with Imperial College London and the University of Vienna, Austria, have identified antibodies that can efficiently neutralize both the dengue virus and the Zika virus. The description of the binding site for these antibodies on the viral envelope, identical for both viruses, could lead to the development of a universal...
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Document de presse | 2016.06.30
The relentless dynamism of the adult brain
Scientists from the Institut Pasteur and the CNRS were able to make real-time observations over a period of several months that reveal how new adult-born neurons are formed and evolve in the olfactory bulb of mice. They made the surprising discovery that there is constant structural plasticity in the connections established by these new neurons with the circuits into which they are recruited. The...
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Document de presse | 2016.07.07
Phage therapy: fundamental action mechanisms revealed
In an article published in PLoS Genetics on July 5, scientists from the Institut Pasteur and the Belgian-based Université catholique de Louvain identify for the first time the genetic and metabolic mechanisms underpinning the therapeutic action of a bacteriophage known for its therapeutic potential. Given the worrying rise in bacterial resistance to antibiotics and the difficulties in developing...
