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Document de presse | 2017.07.20
Gene therapy: first results in children with Sanfilippo B syndrome
On July 13, 2017, the journal Lancet Neurology published the results of a gene therapy trial conducted in four children with Sanfilippo type B syndrome (also known as MPS IIIB). This trial is the achievement of a two-decade partnership with financial support of AFM-Téléthon and the cooperation of the charity "Vaincre les Maladies Lysosomales" (VML). After monitoring of the treated children for 30...
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Document de presse | 2020.10.08
AIDS: Furthering Knowledge of Natural HIV Infection Control Mechanisms
A further step has just been taken in understanding the mechanisms that allow some individuals to control HIV infection without treatment.A research team led by Dr. Asier Sáez-Cirión (Institut Pasteur) and Dr. Bruno Vaslin (IDMIT[1], CEA-Inserm-Université Paris Saclay) observed for the first time that the antiviral activity of CD8+ T cells of "controller" macaques infected with the simian...
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Document de presse | 2021.07.21
SARS-CoV-2 damages ciliated cells and inhibits mucociliary clearance in the airways
COVID-19 is a viral disease with respiratory symptoms that can induce fatal pneumonia. Understanding how SARS-CoV-2 spreads in the respiratory tract can help scientists identify the parameters controlling the severity of infection. Scientists from the Institut Pasteur, the CNRS and Inserm found that SARS-CoV-2 multiplies efficiently in the respiratory tract, and that it primarily targets ciliated...
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News | 2023.01.30
Hepatitis B: towards better treatment for infected individuals in Africa
With 82 million people currently infected in Africa, the hepatitis B virus represents a major health threat. Early treatment can considerably reduce the risk of complications associated with the disease. In a recent analysis, scientists challenged the suitability of the diagnostic tests used in sub-Saharan Africa and called for more optimized treatment for local populations.
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Document de presse | 2023.12.06
Plasmodium vivax malaria: infections may be largely underestimated in sub-Saharan Africa
Researchers from the Institut de Parasitologie et de Pathologie Tropicale at the University of Strasbourg and the Laboratoire de Parasitologie et de Mycologie Médicale at the Strasbourg University Hospital, in collaboration with King's College London, UK, the Institut Pasteur (Paris, France), the Institut Pasteur de Madagascar and the University of Addis Ababa, Ethiopia, have revealed how...
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Document de presse | 2023.12.05
COVID-19: the persistence of SARS-CoV-2 in the lungs and the role of innate immunity
One to two weeks after contracting COVID, the SARS-CoV-2 virus generally becomes undetectable in the upper respiratory tract. But does that mean that it is no longer present in the body? To find out, a team from the Institut Pasteur specialized in HIV, in collaboration with a French public research institute, the Alternative Energies and Atomic Energy Commission (CEA), conducted a study on lung...
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Événement | 2022.11.24
Colloquium for the centenary of Alphonse Laveran’s death
The French Defence Central Health Service ("Service de Santé des Armées" or SSA) pay a scientific and historical tribute to Alphonse Laveran, with a symposium on November 24, 2022 at the Val-de-Grâce School, to mark the centenary of his death. This event is organized with the scientific sponsorship of the Académie nationale de médecine (National Academy of Medicine) and the Institut Pasteur in...
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Document de presse | 2014.11.11
Sanofi - Institut Pasteur Awards 2014
Paris, France - November 13, 2014 - Sanofi and the Institut Pasteur awarded the Sanofi - Institut Pasteur awards for the third consecutive year. Four internationally renowned researchers were honored today for their work carried out in two major fields concerning world health: neglected tropical diseases and immunology.Press releaseNovember 13th, 2014 Created in 2012, these awards encourage...
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News | 2018.02.28
The factors that most affect our immune system
Why do we respond differently to infections or vaccines? Why are some people allergic to pollen? These are still unanswered questions in biological and medical science. The Milieu Intérieur Laboratory of Excellence coordinated at the Institut Pasteur by CNRS research director, Dr. Lluis Quintana-Murci, has recently described immune variation on a large scale within the French population. To...
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Document de presse | 2020.04.24
Development and evaluation of four serological assays to detect SARS-CoV-2 antibodies and two assays to detect neutralizing antibodies
Approximately four months after the initial description of cases of atypical pneumonia in Wuhan, China, in December 2019, COVID-19 had become a major pandemic threat. By April 12, 2020, around half of the world's population was in lockdown, with 1.8 million officially diagnosed cases. Scientists from the Institut Pasteur, the CNRS, Inserm and Université de Paris conducted a pilot study to...