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2020.03.20
The 3D organization of chromosomes plays a role in many biological processes. The ring formed by the cohesin complex is an important regulator of this...
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2021.07.23
In recent years, the scientific community has realized that different bacterial strains can play very different roles in an environment. The identification of...
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2021.07.19
Replication of SARS-CoV-2, the virus responsible for COVID-19, depends on a series of interactions between viral proteins and different cellular partners such...
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2021.06.01
The structure of DNA and chromosomes is a major focus of research, but still holds a number of mysteries. Scientists from the Institut Pasteur and the CNRS...
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2021.05.21
Dominant optic atrophy (DOA) is one of the most common forms of mitochondrial disease. It can be caused by genetic mutations in OPA1 resulting in mitochondrial...
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2020.10.17
Ludovic Deriano’s Unit studied cells mutated for NHEJ, the canonical repair pathway for DNA double-strand break. The researchers showed that those transformed...
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2020.03.27
Replicative DNA polymerases have evolved the ability to copy the genome with high processivity and fidelity. In Eukarya and Archaea, their processivity is...
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2020.07.22
Aptamers can be thought of as analogs of antibodies entirely composed of nucleic acids (DNA or RNA). They can be used in a wide range of applications but they...
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2021.03.08
Tuberculosis is one of the most deadly infectious diseases in the world, and it is the most deadly disease in Europe's history. It is generally caused by the...
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2021.02.15
Since the beginning of the COVID-19 pandemic, words that just a year ago would have been the preserve of scientists have entered everyday language. One example...