Course

Human population genomics and genetic epidemiology

Epidemiology and Public Health
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This two-week course presents theoretical lectures, research examples and hands-on computer training on concepts and tools used in the study of human population genomics and genetic epidemiology. The practical training (computer laboratory work and discussion of the results) is based on real-data examples, using infectious diseases as a paradigm.

Practical information

Institut Pasteur
September 30-October 11, 2019
June 22, 2019
In English

Diplomas

Credits for a Master 2 degree Université de Paris
Credits for a Master 2 degree Sorbonne Université
Doctoral School Module
Institut Pasteur Diploma

The first week consists in an alternation of detailed theoretical bases and hands-on-computer training sessions focusing on the concepts and tools used in genetic epidemiology.

Topics include:

  • Introductory concepts in human genomics and populations genetics.
  • Basic concepts in statistical genetics and genomics.
  • Public databases in human genomics (HapMap, 1,000 Genomes).
  • Introduction to genetic epidemiology.
  • Linkage analyses: principles, methods and hands on computer
  • Association studies – from linkage disequilibrium to genome-wide association studies: principles, methods and hands on computer
  • Next Generation Sequencing – design and analysis of whole exome sequencing studies: principles, methods and hands on computer

 

The second week consists in an alternation of detailed theoretical bases and hands-on-computer training sessions focusing on the concepts and tools used in population genomic.

Topics include :

  • Principles in population genetics
  • Population structure and human demography
  • Natural selection and genetic adaptation: research examples, principles, methods and hands on computer
  • Genome-wide scans for selection: research examples, principles, methods and hands on computer
  • Genetics of gene expression and beyond: research examples, principles, methods and hands on computer
  • Keynote lectures

Candidates must have basic knowledge in molecular genetics, statistics and informatics.

The course committee will evaluate applications.


 

 

More informations

Director(s)

Lluis Quintana-Murci

Human Evolutionary Genetics Unit

Institut Pasteur

 

Aurélie Cobat

Institut IMAGINE

Necker Medical School

 

HONORARY DIRECTOR

Laurent Abel

Human Genetics of Infectious Diseases

INSERM U. 980

Necker Medical School

Attendees
25
Duration
Two weeks
Members of the Course committee

L. Abel (Inserm-Necker)

A. Cobat (Inserm-Necker),

S. Garnier (Sorbonne Université),

M. Lucas-Hourani (Institut Pasteur),

S. Lyonnet (Université de Paris),

V. Ponticelli (Institut Pasteur),

L. Quintana-Murci (Institut Pasteur),

S. Malot (Institut Pasteur),

M. Sala (Institut Pasteur),

H. Waxin (Institut Pasteur),

A. Zider (Université de Paris)

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