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Fiche maladie | 2016.07.08
Staphylococci
Staphylococci are pathogenic bacteria responsible for a broad spectrum of diseases with varying degrees of severity. They are one of the main causes of nosocomial infections (hospital-acquired infections) but can also be acquired outside hospitals. They are part of the natural skin flora, specifically colonizing external mucous membranes, but they are also often found in the environment (in...
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Document de presse | 2016.11.03
Diagnosis of Alzheimer's disease: llama antibodies detect cerebral lesions
The major challenge facing physicians treating Alzheimer's is the ability to detect markers of the disease as early as possible. These markers, located in the brain, are difficult to access, hampering diagnosis. Using two types of llama antibody capable of crossing the blood-brain barrier, scientists from the Institut Pasteur, Inserm, the CNRS, the CEA, Pierre & Marie Curie and Paris...
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Document de presse | 2016.09.19
Too much fat rapidly disrupts the balance of the gut microbiota
A destabilizing factor such as a change in diet can disrupt the entire gut microbiota, with possible health consequences. An international study led by the Molecular Microbial Pathogenesis Unit (Institut Pasteur/Inserm), directed by Philippe Sansonetti, has recently demonstrated in mice that a high-fat diet has a direct influence on the gut microbiota and its environment. Bacterial communities...
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News | 2016.11.08
The Ebola virus adapted to better infect humans during the 2013-2016 epidemic
An international coalition of scientists* involving teams from the Institut Pasteur, has revealed that adaptive mutations to the Ebola virus occurred during the epidemic that swept across West Africa from 2013 onwards. In what remains the most devastating outbreak of this disease ever recorded, it was already known that several strains of the virus circulated at the same time. This new functional...
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Article | 2017.02.27
TT-RIIP International Course
TRANSGENIC TECHNOLOGIES in MODELING HUMAN DISEASES: Principles, Associated Technologies, Animal Management and Ethics
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Article | 2017.03.09
Persistent Viral Infections and Immune evasion
SummaryThis course is located at the intersection between virology and immunology. The aim of the course is to educate graduates and post-graduates with understanding and expertise in virology, with a particular focus on persistent viruses and the mechanisms by which viruses escape from the immune system. This specific theoretical knowledge will provide students with the critical judgement and...
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News | 2017.06.22
A strategy for attenuating a virus by modifying its evolutionary potential
RNA viruses, like influenza viruses, have broad genetic variability, which gives them a high adaptive potential. As part of the fight against RNA viruses, scientists at the Institut Pasteur – evolutionary virologists – decided to alter their future. Along with colleagues from Lund University (Sweden), they succeeded in altering the genomes of an enterovirus and an influenza virus, thereby...
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Fiche maladie | 2017.10.11
Plague
Plague is still rife in Africa, Asia and America. It is considered as one of the world's re-emerging diseases and is subject to international regulations. WHO is reporting an increasing number of cases in some regions. During the 20th century, the use of antibiotic treatments and strengthening of public health measures significantly reduced morbidity and mortality from plague but were not able to...
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Document de presse | 2017.11.21
Gastric cancer: a new strategy used by Helicobacter pylori to target mitochondria
Scientists from the Institut Pasteur and the CNRS have recently identified new strategies used by Helicobacter pylori bacteria to infect cells. By specifically targeting mitochondria these bacteria, despite being extracellular, can optimize infection in the host. These findings pave the way for new strategies to combat H. pylori infection, which is associated with most cases of gastric cancer and...
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News | 2018.03.20
Mamadou Aliou Barry, a lookout against epidemics in Senegal
Physician and epidemiologist, Mamadou Aliou Barry trained between France, Senegal and Laos. Since January 2015, he coordinates the syndromic sentinel surveillance network at the Institut Pasteur in Dakar. This network enables to detect epidemics of febrile illnesses almost in real time thanks to an early warning system.After high school, his classmates all wanted to do math or exact sciences but...