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News | 2018.09.07
Lyme disease: a study on the speed of transmission by infected ticks
Lyme borreliosis is a disease caused by bacteria of the genus Borrelia that are transmitted by a bite from a tick of the genus Ixodes. Scientists from the Institut Pasteur used mice to study the transmission of bacteria by ticks infected with various European and North American species of Borrelia. They found evidence of rapid bacterial transmission following a bite, with infection occurring...
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News | 2019.02.06
A new breakthrough in limb development
Congenital limb defects are very common and occur in 1.5 in 1,000 births. Some are minor, such as a missing finger, while others are more serious, a missing limb for instance. Fundamental biology looks at the buds of developing limbs and how this development may be linked to defects. Limb position is fairly constant within a same species and yet relatively variable in vertebrates. In an article...
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News | 2019.07.25
Aimee Wessel and Raphaël Tomasi win the i-Lab award for their MultiScreen project
On July 4, the i-Lab innovation competition unveiled the names of its 75 winners, which this year included Aimee Wessel and Raphaël Tomasi from the Physical Microfluidics and Bioengineering Unit (Institut Pasteur/École Polytechnique/CNRS). Sponsored by the French Ministry of Higher Education, Research and Innovation and organized in partnership with Bpifrance Financement, i-Lab is France's...
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Portrait | 2018.11.05
Lhousseine Touqui, helping some thanks to others
Driven by curiosity, Lhousseine Touqui has spent many years conducting fundamental research on the respiratory system. Today, his work in the joint Institut Pasteur/Cochin Hospital-PARIS 5 University unit aims to address real needs.Lhousseine Touqui was born in Marrakesh, Morocco where his parents were farmers. He had a gift for mathematics and so specialized in the subject at high school. But...
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Article | 2020.10.05
TECHNOLOGY TRANSFER
Technology Transfer And Business Development OfficeLinda Nait-Kaoudjt, Head of OfficeThe aim of the Technology Transfer Office is to develop partnerships with industrial partners and to increase contract volumes. In order to provide the necessary support and expertise to industrial partners, the mission of the Technology Transfer Office is to identify their medium/long-term strategic...
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Article | 2020.10.14
Covid-19: vaccine against SARS-CoV-2 infection, using the measles vector
Phase I testing in humans for the Institut Pasteur's SARS-CoV-2 vaccine candidate using the measles vector was lauchned in August 2020 in France and Belgium. Following the intermediate results of the Phase I clinical trial, the Institut Pasteur is stopping (January, 2021) development of the vaccine candidate based on the measles platform.
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News | 2021.03.24
World Tuberculosis Day: ERA4TB accelerating the development of new treatment regimens
ERA4TB (the European Regimen Accelerator for Tuberculosis) is a 6-year public-private partnership with a total budget of over €200M that began in 2020 with the goal of accelerating the development of new treatment regimens for tuberculosis (TB). As part of the Innovative Medicines Initiative, ERA4TB brings together experts from academia and pharma, led by Stewart Cole (Institut Pasteur) and David...
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Document de presse | 2021.03.23
SARS-CoV-2 variants of interest can infect mice: host range extended
SARS-CoV-2, the virus responsible for COVID-19, is capable of infecting some species, while others are naturally resistant to it. This determines the "host range" of the virus. The SARS-CoV-2 host range includes humans, non-human primates, hamsters, mink and cats. Since the start of the pandemic, mice and rats had proven to be resistant to SARS-CoV-2, because their ACE2 receptor, which allows the...
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Document de presse | 2021.06.29
Neonatal meningitis: the immaturity of microbiota and epithelial barriers implicated
Meningitis is associated with high mortality and frequently causes severe sequelae. Newborn infants are particularly susceptible to this type of infection; they develop meningitis 30 times more often than the general population. Group B streptococcus (GBS) bacteria are the most common cause of neonatal meningitis, but they are rarely responsible for disease in adults. Scientists from the Institut...
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Document de presse | 2022.02.25
Discovery of an innate immunological memory in the intestine
The innate immune system plays a crucial role in regulating host-microbe interactions, and especially in providing protection against pathogens that invade the mucosa. Using an intestinal infection model, scientists from the Institut Pasteur and Inserm discovered that innate effector cells – group 3 innate lymphoid cells – act not only during the early stages of infection but can also be trained...