-
News | 2025.11.27
An Innovative Method for Measuring DNA Polymerase Fidelity
In collaboration with New England Biolabs, the DNA Replication research group led by Ludovic Sauguet at the Institut Pasteur has published in Nucleic Acids Research an innovative approach based on PacBio long-read sequencing to precisely characterize the errors made by DNA polymerases with unprecedented accuracy.DNA polymerases (DNAPs), essential enzymes for DNA replication and repair, are the...
-
News | 2025.10.15
Allostery: a revolution in molecular biology, in 1965
In 1965, the discovery of a mechanism known as allostery revolutionized our understanding of regulation in molecular biology. Sixty years on, we look back at a scientific and human journey that ushered in a new era of biochemistry and inspired huge swathes of research being conducted today.
-
Événement | 2025.10.08
Open House at the Institut Pasteur, on October 8
On October 8, 2025, the Institut Pasteur will open the doors of its campus in Paris, as part of its annual fundraising event called Pasteurdon. Lab tours, hands-on workshops, storytelling walks, and more (all in French). A day designed for children from 5 to 11 and their families. Free – registration required – limited admissions.
-
News | 2025.07.25
Neutralizing human monoclonal antibodies against hepatitis E virus
The Humoral Immunology Unit has identified neutralizing antibodies that are effective against the hepatitis E virus (HEV). They could be used for prevention or treatment against HEV infection, which affects approximately 20 million people worldwide every year. Structural analyses carried out with the NanoImaging Core Facility enabled atomic-scale visualization of the neutralization site...
-
News | 2025.07.15
Training minds, advancing science: the Institut Pasteur strengthens its philanthropic program for education
Since its founding, the Institut Pasteur has been committed to training scientists and health professionals who address major global health challenges. Today, in a rapidly evolving world, this commitment enters a new phase with the launch of a structured program to support education, aimed at strengthening access, quality, and impact of the scientific training provided by the Institut Pasteur.
-
News | 2025.05.21
Bacteria use the same tools to resist antibiotics and viruses
The severity of the bacterial antibiotic resistance phenomenon is growing, creating a major public health problem. One possible alternative to antibiotics involves the use of phages, or viruses that infect bacteria. However, a recent study has demonstrated that one of the principal resistance mechanisms used by bacteria against antibiotics is also used against phages. This work highlights the...
-
Article | 2025.05.16
European Consortium for Zoonotic and Emerging Viruses - EURL-PH-ERZV
Member of the Consortium of EU Public Health Reference Laboratories for emerging, rodent-borne and zoonotic viral pathogens (EURL-PH-ERZV)
-
Article | 2025.01.20
Genomes and Genetics
Exploring the genomes of bacteria, yeast, insect vectors and ultimately humans: that is the task of scientists in the Department of Genomes & Genetics. By investigating both simple and highly complex organisms, these scientists endeavor to shed new light on the nature of their genetic information.
-
News | 2024.12.16
Microbiota tailored skin humoral immunity and its potential for the development of novel vaccinal approaches
Scientists have just made two major discoveries about a harmless bacterium, Staphylococcus epidermidis, present on our skin. A first study identifies the skin as a compartment able to develop highly protective antibody responses to skin colonizing microbe in the absence of inflammation or lymph node contribution. A second study concerns the development of a topical vaccine that can be applied...
-
Document de presse | 2024.10.15
Resistance mutations to nirsevimab are rare in respiratory syncytial virus (RSV)
Nirsevimab is an antibody targeting the respiratory syncytial virus (RSV). Available in France since September 2023, it is indicated in neonates and infants for the prevention of bronchiolitis caused by RSV. However, its widespread use raises the question of the emergence of resistance mutations. The POLYRES study, the largest prospective surveillance study of nirsevimab breakthrough infections...