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News | 2019.01.28
A new biochemical pathway implicated in the proliferation of cancer cells
Mitochondria are organelles that provide most of the energy necessary for the cell. This energy is provided in “tokens” of adenosine triphosphate, or ATP, a molecule that is required in most chemical reactions and that is essential for all biological processes, such as locomotion, cell division, and transfer of material across membranes. Cancer cells also require energy to proliferate, and for...
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News | 2019.01.28
How human pathogens may emerge from the environment
Legionella pneumophila is an opportunistic human pathogen that is increasingly recognized as an important cause of both community and nosocomially acquired pneumonia (Legionnaires’ disease or legionellosis) worldwide. Researchers from the Institut Pasteur tried to understand how a harmless environmental bacterium can become a feared human pathogen.This human disease represents up to 5% of...
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Report | 2019.01.28
Yellow fever, the story of a re-emerging virus
With outbreaks in Angola in 2015 and Brazil in 2016, and cases detected in French Guiana in 2017 and even recently in Asia, where the virus had never previously been witnessed, yellow fever – a sometimes fatal mosquito-borne disease – has once again become a global public health problem. After major outbreaks between the 17th and 19th centuries, it never disappeared and has continued to be rife...
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News | 2019.02.05
The web meets genomics: a DNA search engine for microbes
Microbes are the most common and diverse organisms on the planet. In recent years, researchers have accumulated data about them, particularly with respect to their genetic background. This avalanche of information - known as "Big Data" - is a fantastic source of new knowledge and medical progress. Researchers at the Institut Pasteur and EMBL’s European Bioinformatics Institute have combined their...
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News | 2019.01.28
Insecticide resistance genes affect vector competence for West Nile virus
In a context of overuse of insecticides, which leads to the selection of resistant mosquitoes, it is already known that this resistance to insecticides affects interactions between mosquitoes and the pathogens they transmit. Researchers from the Institut Pasteur (Paris) and its partners prove that mechanisms of insecticide resistance, observed in Culex quinquefasciatus vector, impact the...
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News | 2019.01.23
The shape of the heart as explained by Audrey Desgrange
The acquisition of the form of an organ is essential to its function. Discover the fascinating work about the shape of the heart, made by Audrey Desgrange, researcher at the Institut Pasteur and the Imagine Institute and laureate of an L'Oreal-UNESCO For Women in Science Award.Audrey Desgrange is a postdoctoral fellow in Sigolène Meilhac's Coordination of Cells and Morphogenesis team at the...
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News | 2019.01.30
When the structure of Tunneling nanotubes (TNTs) challenges the very concept of cell
Cells in our bodies have the ability to speak with one another much like humans do. This communication allows organs in our bodies to work synchronously, which in turn, enables us to perform the remarkable range of tasks we meet on a daily basis. One of this mean of communication is ‘tunneling nanotubes’ or TNTs. In an article published in Nature Communications, researchers from the Institut...
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News | 2019.02.06
A new breakthrough in limb development
Congenital limb defects are very common and occur in 1.5 in 1,000 births. Some are minor, such as a missing finger, while others are more serious, a missing limb for instance. Fundamental biology looks at the buds of developing limbs and how this development may be linked to defects. Limb position is fairly constant within a same species and yet relatively variable in vertebrates. In an article...
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Page avancée | 2019.02.14
Pasteur Network
The Institut Pasteur is proud to be a member of the Pasteur Network.The Pasteur Network is a vast human and scientific communitywith more than 30 members in over 20 countries contributing togetherto the improvement of global health.
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Fiche maladie | 2019.02.19
Alzheimer's disease
Alzheimer's disease is a neurodegenerative disease that mainly affects memory but also has an impact on other cognitive functions, for example those related to language, reasoning and learning. Alzheimer's disease generally leads to a loss of independence. It is one of the leading causes of disability and dependency in elderly people worldwide. There is currently no treatment for Alzheimer's...
