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Document de presse | 2018.11.22
How bacteria invade us – Pascale Cossart honoured with 2018 Heinrich Wieland Prize
Professor Pascale Cossart of the Institut Pasteur in Paris will be honoured with the 2018 Heinrich Wieland Prize for her fundamental contributions to Molecular Infection Biology. Cossart’s innovative research has unravelled how pathogenic bacteria, in particular food-borne Listeria, enter human cells, use the host cells’ own mechanisms to do so, and trick and evade the immune system. Her...
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News | 2018.11.22
An update on the Institut Pasteur's work on CRISPR-CAS9
What is CRISPR-CAS9? This system is used by bacteria to defend themselves against the viruses that attack them. But what are their technological applications? How are they used in David Bikard's laboratory? This researcher from the Institut Pasteur explains his work. David Bikard, head of the Synthetic Biology junior group at the Institut Pasteur, reviews his work on CRISPR-CAS9.
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Document de presse | 2018.11.23
Cancer under pressure: visualizing the activity of the immune system on tumor development
As tumors develop, they evolve genetically. How does the immune system act when faced with tumor cells? How does it exert pressure on the genetic diversity of cancer cells? Scientists from the Institut Pasteur and Inserm used in vivo video techniques and cell-specific staining to visualize the action of immune cells in response to the proliferation of cancer cells. The findings have been...
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News | 2018.11.30
A new step in understanding the mechanisms that control cilia length
Cilia and flagella – cellular projections attached to the membrane – are involved in numerous processes, for example sensory signal reception or cell movement. The diseases affecting these projections, ciliopathies, result from defects linked to cilia and flagella length. Institut Pasteur scientists have tried to unravel the mechanisms controlling the length of the appendages in the hope of...
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Fiche maladie | 2018.12.05
Cystic fibrosis
Cystic fibrosis is the most common severe hereditary genetic disease in the Caucasian population. It is an autosomal recessive inherited disease of the CFTR gene. This fatal condition is characterized by respiratory impairment that affects approximately one in every 2,500 births in Europe and North America. Although the life expectancy of affected individuals has risen considerably since the...
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News | 2018.12.10
Demystifying immunity in the bladder
A European Union-funded project set out to study the bladder's immune system, with the aim of advancing our understanding of UTI and bladder cancer to improve treatment of these diseases. Dr. Molly Ingersoll, researcher at the Institut Pasteur, is leading the project.We know that the bladder is a poorly understood organ, critical for storing metabolic waste. What we don’t know is how this unique...
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News | 2018.12.11
Distinguishing resistence from resilience to prolong antibiotic potency
Biomedical engineers at Duke University, in collaboration with Inria and the Institut Pasteur (Paris), have shown experimentally that there is more than one flavor of antibiotic resistance and that it could - and should - be taken advantage of to keep first-line antibiotics in our medical arsenal.In a study appearing online Dec. 7 in the journal Science Advances, the researchers show why doctors...
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News | 2018.12.17
WHO high-level meeting on preparedness in public health emergencies
On December 4th, The Institut Pasteur International Network (IPIN) participated in a high-level meeting on preparedness in public health emergencies and the challenges and opportunities in urban areas organized by World Health Organization (WHO) in Lyon.The objective of this conference was to identify gaps and challenges, to foster intersectoral and multidisciplinary collaboration (including a "...
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News | 2018.12.17
A biological interface for prostheses: the futuristic project of the 2018 Pasteur iGEM team
On December 11, 2018, the Institut Pasteur awarded the 20 students of the 2018 Pasteur iGEM team. They came back with a gold medal from the competition that was held in Boston from October 24 to 28. Each year, the Massachusetts Institute of Technology (USA) organizes the international competition iGEM (Genetically Modified International Machine), which promotes research in synthetic biology. For...
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News | 2018.12.17
Tumor cells eliminating their neighbors using a newly discovered mechanism
How do tumoral cells replace healthy cells to promote tumor progression? Scientists from the Institut Pasteur (Paris, France) and from the Champalimaud Centre for the Unknown (Lisbon, Portugal) identified a mechanism that responds to cell deformation and can be exploited by tumoral cells to squeeze out and kill their neighbors. This mechanism may promote the early expansion of tumors.Despite...
