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News | 2018.03.22
Staphylococcus aureus: a new mechanism involved in virulence and antibiotic resistance
An Institut Pasteur-CNRS research team has characterized a Staphylococcus aureus gene involved in virulence, biofilm formation and resistance to certain antibiotics. These results open up new avenues for understanding the control of S. aureus virulence mechanisms. This work was recently published in the journal PLoS Pathogens.Staphylococcus aureus is part of the natural skin flora, preferentially...
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News | 2018.04.09
Avian flu: Cambodian markets under heavy surveillance
Celebrated every year in mid-April, Bon Chaul Chhnam, the Khmer New Year, is one of the most important festivals in Cambodia. For the Institut Pasteur du Cambodge Virology Unit, it is also a time of intense mobilization. Supported by the Cambodian National Animal Health and Production Research Insititute, the researchers pay frequent visits to the live poultry markets to monitor the circulation...
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News | 2018.03.23
Multiscale structure of the Escherichia coli genome
The Escherichia coli bacterium is a major focus of research in biology. But the higher-order organization of its genome had yet to be investigated using techniques such as chromosome conformation capture (3C/Hi-C). In a paper published in the journal Cell, scientists from the Institut Pasteur revealed using this approach the existence of several levels of chromosomal folding linked to known...
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Article | 2018.03.28
ASIDE project: Surveillance and health alerts
In a context of increasing globalization of trade, the growth in international flows of travelers and goods fuels the spread of infectious diseases. The need for a global alert and response network for infectious diseases and public health emergencies of international concern led to the 2005 revision of the International Health Regulations (IHR). Coordinated by the Institut Pasteur, the...
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Document de presse | 2018.03.29
Estimating the effect of genetic mutations on neurodevelopmental disorders more accurately
A recent study, co-edited by Canadian researchers (CHU Sainte-Justine, the Université de Montréal) and French researchers (the Institut Pasteur and the university Paris-Diderot), presents a model that can predict the effect of a genetic variant on a person’s cognitive traits and estimate the impact of genetic mutations on IQ. This discovery opens the way to a better interpretation of genetic...
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News | 2018.03.29
New insight into body's response to killer fungus
Scientists at the University of Aberdeen, with colleagues from several institutions, including the Institut Pasteur, have made a new discovery that could help in the fight against a fungus that kills around 200,000 people every year and causes lung and allergic diseases in millions of others.The study, carried out in collaboration with a number of institutions**, including the Institut...
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Report | 2018.04.03
Autoimmune diseases: when our defenses turn against us
Type 1 diabetes, multiple sclerosis, rheumatoid arthritis, ankylosing spondylitis, psoriasis, systemic lupus erythematosus, vitiligo, Crohn's disease and Guillain-Barré syndrome – these seemingly different diseases all have one thing in common: they occur when a deregulation of the immune system causes it to "attack" the organism that it is supposed to be protecting. These "autoimmune" diseases,...
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News | 2018.03.26
Catherine Rougeot and the discovery of a new painkiller molecule
Catherine Rougeot, an Institut Pasteur guest researcher, was recognized by the Institut Pasteur in 2017 for her work in discovering a non-opioid analgesic, today called STR-324. She was appointed member of the National Academy of Inventors in the US on receiving this award. As the Institut Pasteur is celebrating its 130th anniversary this year – November 14, 2018 – let's look back at the...
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News | 2018.04.03
Spencer Shorte appointed Chief Scientific Officer to Institut Pasteur Korea
In February 2018, Dr Spencer Shorte was named Chief Scientific Officer (CSO) to Institut Pasteur Korea.Graduated in Biochemistry from the University of Kent at Canterbury (UK) in 1988, Dr Shorte received his PhD from Bristol University in 1992. Developing live cell imaging techniques he worked through several post-doctoral fellowships in Europe and a visiting professorship in the USA before being...
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News | 2018.03.27
Just the two of us: Holding hands can ease pain, sync brainwaves
Reach for the hand of a loved one in pain and not only will your breathing and heart rate synchronize with theirs, your brain wave patterns will couple up too, according to a new study. The study, by researchers with CU Boulder and University of Haifa, in collaboration with the Institut Pasteur published in the journal Proceedings of the National Academy of Sciences (PNAS) this week, also...
