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News | 2018.04.18
A project to strengthen National Ethics Committees in Francophone Africa
National Ethics Committees are key actors of the research and civil society world, responsible for assessing complex situations with regard to individual rights and the general interest both in the normal course as well as in times of crisis. When a clinical trial or any research involving individual is conducted, they are responsible for ensuring that research participants are protected and...
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Document de presse | 2018.04.25
Meningococcal meningitis: stomach pain should be seen as a warning sign
Patients with meningococcal infection generally develop symptoms including a high temperature, vomiting and a stiff neck... but they might also just have a bad stomach ache. This can be so severe that they are sometimes wrongly operated for appendicitis. Teams from the Institut Pasteur and the Department of Pediatrics at Bicêtre Hospital (AP-HP) decided to investigate the question. And the...
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Document de presse | 2018.05.23
Dengue: investigating antibodies to identify at-risk individuals
Using an original mathematical and statistical analysis method, a team of scientists from the Institut Pasteur partnered with researchers from the United States and Thailand to analyze a Thai cohort that has long been a focus of study for dengue specialists, and obtained new information that should help identify individuals at risk of infection. By modeling changes in antibody levels after...
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News | 2018.05.23
Ebola: the answers to your questions in our disease sheet
On May 8, 2018, the Ministry of Health of the Democratic Republic of the Congo declared that the Bikoro health zone, in Equateur province, was the scene of an Ebola outbreak. The "Ebola" disease sheet of the Institut Pasteur has just been updated.This new epidemic in the Democratic Republic of the Congo (DRC) is a major risk for the local population. This news is an opportunity to recall that...
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News | 2018.05.25
Regulation of muscle stem cells in their niche: juggling external and internal cues
Little information is available on how stem cells acquire their special properties. A team from the Institut Pasteur has described a signalling pathway (Notch/COLV/CALCR) that proposes a new view on how muscle stem cells are retained in their local microenvironment (niche).Stem cells play critical roles during growth, regeneration and ageing. Although they possess special features that allow them...
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Report | 2018.05.25
From Molecular Biology to Stem Cells
May 1968… While students took to the streets of Paris, Jacques Monod and François Jacob were getting ready for what would prove to be a decisive turning point for the Institut Pasteur: the opening of a new department dedicated to molecular biology—in other words the study of the molecular mechanisms governing cell behavior. The venture, which included plans for purpose-built premises, had...
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News | 2018.05.29
The Institut Pasteur de Nouvelle-Calédonie describes 12 new species of leptospires and pays tribute to Pasteurians
Environmental bacterial disease, leptospirosis causes nearly 1 million clinical infections per year. The Institut Pasteur de Nouvelle-Calédonie has been interested for many years with the disease whose incidence is particularly high in Oceania. Researchers from the Leptospirosis Research and Expertise Unit, led by Cyrille Goarant, recently isolated 12 new species of the genus Leptospira.In an...
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News | 2018.05.28
Artificial intelligence speeds up high-resolution microscopy
Scientists from the Institut Pasteur have developed a method for increasing the spatio-temporal resolution in optical microscopy. This method, called ANNA-PALM, is based on recent developments in artificial intelligence and, more specifically, in much-talked-about deep learning. This article explores the method."Traditional optical microscopes can be used to distinguish structures in the range of...
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News | 2018.05.28
Artificial intelligence: deep learning is blazing ahead
Christophe Zimmer, Head of the Imaging and Modeling Unit at the Institut Pasteur, looks at artificial neural networks, algorithms with learning ability (deep learning), which fuel the renewed interest in artificial intelligence. Artificial intelligence will play a key role in personalized medicine.Christophe ZimmerHead of the Imaging and Modeling Unit at the Institut Pasteur What are...
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News | 2018.05.31
Elliot Rakotomanana, an anthropologist against malnutrition in Madagascar
With a master’s-level degree in the biochemistry of nutrition, Elliot Rakotomanana is currently pursuing his studies in the social anthropology of health. As a researcher at the Institut Pasteur in Madagascar, this 37-year-old is participating in the AFRIBIOTA research program, an innovative multidisciplinary project that seeks better understanding of chronic childhood malnutrition and...
