1. News | 2016.06.22

   Antibodies that are effective against both dengue and Zika viruses

   Scientists have identified antibodies that can efficiently neutralize both the dengue virus and the Zika virus. The description of the binding site for these antibodies on the viral envelope, identical for both viruses, could lead to the development of a universal vaccine that offers simultaneous protection against dengue and Zika virus disease.

2. News | 2016.06.29

   The relentless dynamism of the adult brain

   Scientists were able to make real-time observations over a period of several months that reveal how new adult-born neurons are formed and evolve in the olfactory bulb of mice. They made the surprising discovery that there is constant structural plasticity in the connections established by these new neurons with the circuits into which they are recruited.

3. News | 2016.07.06

   Phage therapy: fundamental action mechanisms revealed

   Scientists identify for the first time the genetic and metabolic mechanisms underpinning the therapeutic action of a bacteriophage known for its therapeutic potential. Given the worrying rise in bacterial resistance to antibiotics and the difficulties in developing effective new molecules, there has been renewed interest within the scientific community in recent years in phage therapy, which...

4. News | 2016.07.17

   Malaria: a genetically attenuated parasite induces an effective, long-lasting immune response

   With nearly 3.2 billion people currently at risk of contracting malaria, scientists from the Institut Pasteur, the CNRS and Inserm have experimentally developed a live, genetically attenuated vaccine for Plasmodium, the parasite responsible for the disease. By identifying and deleting one of the parasite's genes, the scientists enabled it to induce an effective, long-lasting immune response...

5. News | 2016.08.21

   Tunneling nanotubes between neurons enable the spread of Parkinson's disease via lysosomes

   Scientists from the Institut Pasteur have demonstrated the role of lysosomal vesicles in transporting α-synuclein aggregates, responsible for Parkinson's and other neurodegenerative diseases, between neurons. These proteins move from one neuron to the next in lysosomal vesicles which travel along the "tunneling nanotubes" between cells.

6. News | 2016.08.22

   TONIRA : towards better medical care of acute respiratory infections among children in Niger

   In Niger, respiratory infections and pneumonia are the second cause of hospital infant mortality (10 to 20% of deaths according to health authorities information). As in most African countries, few data on surveillance and etiology of these infections are available whereas they are essential to guide public health policies. In addition in Niger, antibiotic treatment for acute respiratory diseases...

7. News | 2016.08.28

   Alzheimer's: nicotinic receptors as a new therapeutic target

   Several scientific studies have indicated that nicotine may be beneficial for memory function. Scientists from the Institut Pasteur and the CNRS set out to shed further light on the properties attributed to nicotine – which is known to have an adverse effect on health – by determining the precise structure of the nicotinic receptors in the hippocampus region of the brain. Using mouse...

8. News | 2015.01.07

   #JeSuisCharlie

   In this day of National Mourning, the Institut Pasteur expresses its deep sadness and supports all people and families affected by this tragedy. #JeSuisCharlie

9. News | 2015.01.08

   Resident and recruited macrophages orchestrate the liver's defense against infection

   Scientists have demonstrated that liver-resident macrophages are rapidly killed by the pathogenic bacterium Listeria monocytogenes. This early death triggers the recruitment of macrophages from the bloodstream to the liver. These macrophages start by bringing the bacterial infection under control; then, in an unexpected development, they actually replace the liver-resident macrophages that have...

10. News | 2015.01.13

    Identification of an Achilles heel in the dengue virus gives new hope for vaccine development

    Scientists have identified a vulnerable site on the surface of the dengue virus which is targeted by the only broadly neutralizing antibodies identified to date. This discovery offers a new target for the development of a vaccine to combat all four types of dengue virus currently in circulation.

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