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News | 2021.11.10
COVID-19: Kamala Harris, Vice President of the United States, salutes the Institut Pasteur's response in tackling the pandemic
As part of her trip to France for the fourth Paris Peace Forum – which includes three round tables on the challenges raised by the COVID-19 pandemic –, Kamala Harris, Vice President of the United States, visited the Institut Pasteur on November 9, 2021. She met several of the Institut Pasteur's scientists and saluted the unprecedented response of the Institut Pasteur's scientific community in...
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News | 2018.02.28
The factors that most affect our immune system
Why do we respond differently to infections or vaccines? Why are some people allergic to pollen? These are still unanswered questions in biological and medical science. The Milieu Intérieur Laboratory of Excellence coordinated at the Institut Pasteur by CNRS research director, Dr. Lluis Quintana-Murci, has recently described immune variation on a large scale within the French population. To...
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News | 2019.12.09
Institut Pasteur team identifies a key protein linked to ageing
Ageing is a dramatic public health issue in the face of the current demographic changes: the proportion of 60 and over in the world’s population will almost double by 2050. In this context, a new discovery has just broadened scientific knowledge. Researchers from the Developmental and Stem Cell Biology Department at the Institut Pasteur shed light on the mechanisms of senescence, by identifying a...
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Document de presse | 2018.12.20
AIDS – an approach for targeting HIV reservoirs
Current HIV treatments need to be taken for life by those infected as antiretroviral therapy is unable to eliminate viral reservoirs lurking in immune cells. Institut Pasteur scientists have identified the characteristics of CD4 T lymphocytes that are preferentially infected by the virus – it is their metabolic (or energy-producing) activity1 that enables the virus to multiply. Thanks to...
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Document de presse | 2012.02.08
New results underline the importance of synaptic genes in autism
Autism has been declared a major national cause for 2012, and will have a high profile in France throughout the whole year. Paradoxically, this syndrome – and its causes in particular – remains poorly understood. A study published on February 9, 2012, in Public Library of Science - Genetics, shows that genetic mutations interfering with communication between neurons are directly...
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Document de presse | 2018.06.01
Announcement of the 2018 ALBERT EINSTEIN World Award of Science
Prof. Jean-Pierre Changeux, Emeritus Professor of Neuroscience at the Institut Pasteur and Collège de France, where he was Chair of Cellular Communications from 1976 to 2006, and at the International Faculty, Kavli Institute for Brain & Mind, University of California (San Diego), has been selected as the winner of the 2018 ALBERT EINSTEIN World Award of Science. The prize is awarded in...
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Document de presse | 2018.08.22
Chronic malnutrition in children: a new gut microbial signature
Chronic malnutrition, usually associated with an inflammation of the small intestine, affects one in every four children under the age of five. It is the leading cause of child mortality in low-income countries and is also responsible for severe stunting. The Afribiota project, led by the Institut Pasteur in Paris, the Institut Pasteur in Madagascar and the Institut Pasteur in Bangui, in...
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News | 2019.07.12
Sex-based differences influence chronicity in urinary tract infections
Research efforts in recent years have highlighted that sex - being a woman or a man - can have a strong influence on how humans and animals respond to many types of infections. Researchers at the Institut Pasteur have identified a sex-based difference in the early immune response to infection in a model of urinary tract infection in female and male animals. Interview "Tête-à-tête" with Molly...
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Document de presse | 2019.07.12
HIV: reprogramming cells to control infection
Cells from the rare individuals who naturally control HIV infection have been the focus of investigation for nearly 15 years with the aim of elucidating their specific features. Following research on the ANRS CO21 CODEX and CO6 PRIMO cohorts, scientists from the Institut Pasteur have described the characteristics of CD8 immune cells in these "HIV controller" subjects. The unique antiviral power...
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Document de presse | 2022.03.29
SARS-CoV-2: neutralization of BA.1 and BA.2 by therapeutic monoclonal antibodies
The SARS-CoV-2 Omicron BA.1 sublineage has been supplanted in many countries by the BA.2 sublineage. Although Omicron is responsible for less severe forms in the general population, immunocompromised people are still at higher risk of developing severe forms of COVID-19. Several monoclonal antibodies are currently available in clinical practice as a preventive treatment for these patients....