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News | 2020.04.22
Neurodevelopmental disorders: a daily practical guide by InovAND to help families deal with the difficulties of lockdown
Institut Pasteur partner InovAND, the Excellence Center in the Greater Paris region specializing in autism spectrum and neurodevelopmental disorders, is publishing a practical guide every day to help families overcome the difficulties associated with the lockdown.The lockdown soon proved to be a testing time for many families, especially those with a child affected by neurodevelopmental disorders...
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News | 2020.06.02
The hidden population of multidrug-resistant Klebsiella bacteria colonizing the human digestive tract
Klebsiella bacteria are responsible for some of the most antibiotic-resistant infections. A major study on intestinal colonization by Klebsiella has shed light on human carriage of these strains in the community (i.e. outside hospitals) in low-income countries. This study reveals that controlling Klebsiella carriage is a complex challenge.It is normal to find Klebsiella bacteria inhabiting the...
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News | 2020.12.02
Diphtheria: identification of a penicillin resistance gene
Before the vaccine era, diphtheria was the most deadly respiratory infection in young children. There are still outbreaks of diphtheria in some world regions and cases can occur among unvaccinated individuals, with severe consequences. Antibiotics are vital in treating diphtheria, and the emergence of antibiotic resistance is a major public health concern. A team of Institut Pasteur scientists...
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Document de presse | 2020.12.28
COVID-19: optimizing surveillance in long-term care facilities
Throughout the world, long-term care facilities have been high-risk sites for virus spread since the emergence of the COVID-19 epidemic. In this context, the capacity for timely surveillance and control of case numbers is essential in such facilities. Scientists at the Institut Pasteur have joined forces with the University of Versailles-Saint-Quentin-en-Yvelines, Inserm, and the National...
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News | 2021.03.30
Mobilization of the Institut Pasteur International Network to manage the COVID-19 outbreak: case study of support provided to the Institut Pasteur de Bangui
Since the beginning of the COVID-19 pandemic, and increasingly rapidly thereafter, the Institut Pasteur International Network has drawn heavily on all its expertise and resources to tackle this emerging virus and its consequences, particularly through its support of institutes based in low-income countries. All Network member institutes have been identified by their health authorities as...
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Document de presse | 2021.04.21
SARS-CoV-2: infection induces antibodies capable of killing infected cells regardless of disease severity
Drawing on epidemiological field studies and the FrenchCOVID hospital cohort coordinated by Inserm, teams from the Institut Pasteur, the CNRS and the Vaccine Research Institute (VRI, Inserm/University Paris-Est Créteil) studied the antibodies induced in individuals with asymptomatic or symptomatic SARS-CoV-2 infection. The scientists demonstrated that infection induces polyfunctional antibodies....
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Document de presse | 2022.04.14
Decoding a direct dialog between the gut microbiota and the brain
Gut microbiota by-products circulate in the bloodstream, regulating host physiological processes including immunity, metabolism and brain functions. Scientists from the Institut Pasteur (a partner research organization of Université Paris Cité), Inserm and the CNRS have discovered that hypothalamic neurons in an animal model directly detect variations in bacterial activity and adapt appetite and...
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Document de presse | 2022.07.21
SARS-CoV-2 hijacks nanotubes between neurons to infect them
COVID-19 often leads to neurological symptoms, such as a loss of taste or smell, or cognitive impairments (including memory loss and concentration difficulties), both during the acute phase of the disease and over the long term with "long COVID" syndrome. But the way in which the infection reaches the brain was previously unknown. Scientists from Institut Pasteur and CNRS laboratories have used...
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Document de presse | 2022.12.20
Identification of a new neural pathway essential for refining odor perception
In the brain, sensory messages are processed by neurons that send the information collected by the sensory organ to the different structures of the brain. At each stage of integration, the activity of these neurons is controlled by interneurons that exert local inhibition in order to direct and modulate the neural messages. This type of circuit forms the classical architecture of the sensory...
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Document de presse | 2023.09.08
How the respiratory tract microbiome influences the severity of bacterial pneumonia
Pneumonia is an infection of the lung alveoli caused by bacteria, viruses or fungi. It is one of the leading causes of morbidity and mortality worldwide, representing a clinical and economic burden and a global public health problem. The microbial ecosystem (or microbiome) of the human respiratory tract colonizes different niches. The respiratory tract microbiome is of interest to scientists as...