Mouse genetics

Mechanisms of Living Organisms

This five-week intensive laboratory and lecture course covers the analysis of gene function at all levels: the gene and its product, the cell and its interactions, the embryonic tissues and the animal as a whole.

Practical information

Institut Pasteur
January 6-February 11, 2020 (exam included)
September 15, 2019
In English


Credits for a Master 2 degree Université de Paris
Credits for a Master 2 degree Sorbonne Université
Credits for a Master 2 degree Paris Sud
Doctoral School Module
Institut Pasteur Diploma
University diploma Paris Diderot

This course offers a full training program for advanced graduate and PhD students, as well as post graduate biologists and medical doctors willing to work on medical and experimental Mammalian Genetics.

The themes of the course:

The theoretical part of this course deals, in particular, with genetic analysis of mendelian and quantitative traits, phenotypic analysis of genetic variants, early embryo biology, pluripotent stem cells, cellular and molecular mechanisms controlling embryogenesis, models to study oncogenes and tumor suppressor genes, methods to study cell lineage in mouse embryos, genome editing and conditional expression systems for transgenes, optogenetic approaches and the role of small RNAs.

The practical part presents methods and techniques used to derive induced pluripotent stem cells (iPS) from differentiated cells, to study behavioral traits, to analyze gene function in embryonic and adult mutants, to map mendelian traits of Masters, and to identify QTLs. It also illustrates the use of RNA interference to silence gene expression.

Student opinion on the Mouse Genetics Course

According to recent opinion surveys, 100% of the students felt that the course fulfilled their expectation, covers the topic, and offers very good or excellent lectures. The general organization and the program were qualified as very good or excellent by all attendees. From free comments: "Effective teaching through an exchange with the students by an active teaching staff. All this orchestrated by very receptive and well recognized experts", "I really enjoyed the course despite the very busy days of study", "A very big thank for this incredibly rich training", "I really appreciated the quality of lectures and practical trainings. I will recommend this course to other students".

Candidates must have a good knowledge of basic laboratory techniques of Masters degree level. The course committee will evaluate applications.

More informations



Xavier Montagutelli

Mouse Functional Genetics Unit

Institut Pasteur

Michel Cohen-Tannoudji

Mouse Functional Genetics Unit

CNRS, URA 2578

Institut Pasteur


up to 18
5 weeks
Members of the Course committee

J. Artus* (Université Paris Saclay),

M. Cohen-Tannoudji (Institut Pasteur),

A. Lalouette* (Université de Paris),

M. Lucas-Hourani (Institut Pasteur),

S. Malot (Institut Pasteur),

X. Montagutelli (Institut Pasteur),

V. Ponticelli (Institut Pasteur),

B. Robert (Institut Pasteur),

M. Sala (Institut Pasteur),

L. Tiret(ENVA),

F. Toledo* (Sorbonne Université),

H. Waxin (Institut Pasteur).

* University Representatives

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