Course

Molecular biology of the cell

Mechanisms of Living Organisms
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This four-week intensive laboratory and lecture course is organized in collaboration with the Institut Curie; it is devoted to the presentation of current concepts and new experimental techniques in the study of cellular functions.

Practical information

Institut Pasteur
January 13-February 14, 2020
September 8, 2019
In English

Diplomas

Credits for a Master 2 degree Université de Paris
Credits for a Master 2 degree Sorbonne Université
Credits for a Master 2 degree Paris Sud
Doctoral School Module
Institut Pasteur Diploma
University diploma Paris Diderot

This four-week intensive laboratory and lecture course is organized in collaboration with the Institut Curie; it is devoted to the presentation of current concepts and new experimental techniques in the study of cellular functions.

Topics of lectures include functional organization of the cell, polarity and intracellular traffic communication, cellular signaling, cell migration and invasion, stem cells, apoptosis, autophagy, cell-pathogen interactions, cell cycle and mitosis.

The practical course provides training in culture of transfected and infected cells, in vitro reconstitution of cellular functions, gene inactivation and cutting edge techniques of live imaging.

The first module: Vesicular trafficking and signaling (January 13-24) will focus on mechanistic processes that regulate the dynamics of proteins and lipids at the plasma membrane. The practicum will study caveolae dynamics and carbohydrate-based mechanisms to build endocytic pits using chemical biology and imaging techniques.

The second module: Cell shape and morphogenesis (January 27-February 7) will review key biological concepts required to understand mechanical forces and collective migration in development and morphogenesis. The practicum will study the formation of multicellular tubes in vitro, using micropatterns and microfuidics, ans in vivo, using Drosophila and zebrafish embryos.

Applicants may opt to take only one module or the entire course


Fellowships (1.500 Euros) will be awarded to the three best applicants from foreign countries to cover, in part, their travel accommodation expenses.

The final exam for participants not enrolled in a master 2 program of a partner university will take place on Friday February 7, 2020; master 2 students from partner universities will take the final exam on February 14, 2020.


Candidates must have a good knowledge of basic laboratory techniques at the Master degree level. The committee of the course will evaluate applications.


> See this course on the Institut Curie website

More informations

Director(s)

Roberto Bruzzone

HKU-Pasteur Research Pole

Hong-Kong SAR, P.R. China

 

Philippe Chavrier

CNRS UMR 144

Institut Curie

 

Chiara Zurzolo

Membrane traffic and pathogenesis unit

Institut Pasteur

Attendees
20
Duration
4+1 weeks
Members of the Course committee

R. Bruzzone (HKU-Pasteur Research Pole, Hong Kong, SAR P.R. China),

P. Charnay (Ecole normale supérieure, Paris),

P. Chavrier (Institut Curie),

M. H. Cuif* (Université Paris Saclay),

O. Kellermann (Institut A. Lwoff),

M. Lucas-Hourani (Institut Pasteur),

V. Ponticelli (Institut Pasteur),

M. Sala (Institut Pasteur),

J. Sobczak-Thepot* (Sorbonne Université),

S. Vriz* (Université de Paris),

H. Waxin (Institut Pasteur),

C. Zurzolo (Institut Pasteur),

* University Representatives

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